Results 241 to 250 of about 108,614 (299)

Network pharmacology refined with non-ubiquity and decoy-controlled molecular docking reveals insights into <i>Moringa oleifera</i> phytochemicals targeting insulin resistance. [PDF]

Front Bioinform
Santos-Enriquez AK, Dayrit FM, de Jesus AJ, Rojas NRL.   +3 more
europepmc   +1 more source

Preclinical Evaluation of Berry Extracts as a Nutritional Intervention to Alleviate Myocardial Ischemia–Reperfusion Injury and Atherosclerosis Development

Phytotherapy Research, EarlyView.
Schematic representation of the experimental design and the proposed mechanisms underlying the cardioprotective and anti‐atherosclerotic effects of Greek‐derived berry extracts. C57BL/6 mice with WD–induced MS and ApoE−/− mice with atherosclerosis received chronic supplementation with WMex or BBex.
Lydia Symeonidi, Panagiota‐Efstathia Nikolaou, Panagiotis Stathopoulos, Andriana Christodoulou, Alexandra Svouraki, Panagiotis Efentakis, Christina Chania, Angeliki Choustoulaki, Maria Xenaki, Anna Agapaki, Maria Tsoumani, Nikolaos Kostomitsopoulos, Ioulia Tseti, Gemma Vilahur, Alexios‐Leandros Skaltsounis, Ioanna Andreadou   +15 more
wiley   +1 more source

Structure-Guided Identification of Phytochemical OCT2 Inhibitors and Their Functional Relevance to Cisplatin-Induced Cytotoxicity. [PDF]

Pharmaceutics
Song H, Lee KR, Li H, Lee MK, Chae YJ.
europepmc   +1 more source

In vitro and in vivo metabolism profiles of cathinone and pseudoephedrine: Discrimination between khat and pseudoephedrine uses

Journal of Forensic Sciences, EarlyView.
Abstract In the present study, the metabolism of khat (Catha edulis) and pseudoephedrine was compared with the aim of identifying objective criteria that could be used to discriminate between them for forensic and doping‐control purposes. An in vitro study using human liver microsomes and an in vivo study using rat urine were performed under harmonized
Jong Suk Park, Jun Sang Yu, Yejin Kim, Hee Seung Kim, Jae Chul Cheong, Jin Young Kim, Hye Hyun Yoo   +6 more
wiley   +1 more source

Herbal Neurotherapeutics for Cognitive Disorders: Integrative Mechanisms Linking Neurotransmitter Systems, Neurodegeneration, and the Gut-Brain Axis. [PDF]

Nutrients
Rahman M, Akter K, Rani A, Park MN, Kim B.   +4 more
europepmc   +1 more source

Kaempferol Protects Intestinal Health in Chinese Forest Musk Deer Possibly by Regulating Intestinal Microbiota and Inhibiting the NF‐κB/NLRP3 Signaling Pathway

Integrative Zoology, EarlyView.
Kaempferol modulates the tryptophan metabolism pathway by increasing the abundances of Christensenellaceae R7 group, Bacteroides, and Blautia and reducing that of Rikenellaceae RC9 gut group, thereby significantly increasing the levels of ILA and IAA. This process inhibits the activation of NF‐κB/NLRP3 signaling pathway, reduces pro‐inflammatory factor
Xiangyu Liu, Zhanjun Ren, Xiuzhu Sun, Shuhui Wang   +3 more
wiley   +1 more source

Deciphering the mechanisms underlying the dual-target inhibition of carbohydrate-digesting and neurodegenerative enzymes by Syzygium aromaticum (L.) Merr. & L.M. via molecular docking and dynamics simulations. [PDF]

Sci Rep
Ojo OA, Gyebi GA, Iyobhebhe M, Dada S, Daramola T, Ojo AB, Oyebamiji AK, Oyinloye BE, Ajiboye BO.   +8 more
europepmc   +1 more source

Enterococcus faecalis and Endodontic Treatment Failure: A Qualitative Systematic Review of Its Role and Elimination Strategies

Australian Endodontic Journal, EarlyView.
ABSTRACT The aim of this study was to synthesize evidence on the influence of Enterococcus faecalis on endodontic treatment failure and strategies for its elimination. This study followed the Preferred Reporting Items for Systematic Reviews and Meta‐Analyses (PRISMA) guidelines and was registered in PROSPERO (CRD420251022741).
Francine Santos Fernandes de Lima, Analia Gabriella Borges Ferraz Facury   +1 more
wiley   +1 more source

<i>In silico</i> identification of isosilybin a targeting squalene epoxidase as an antifungal adjuvant with <i>in vitro</i> validation against azole-resistant <i>Candida</i> and emerging yeasts. [PDF]

Front Cell Infect Microbiol
Mundhe AK, Rajkumari R.
europepmc   +1 more source

In silico characterization of bioactive phytochemicals as antivirals targeting the reovirus σ1 protein for inhibiting σ1-mediated host cell entry. [PDF]

PLoS One
Dey E, Dey S, Nandi L, Mumit SH, Arfat R, Saif SR, Islam MM.   +6 more
europepmc   +1 more source