Results 51 to 60 of about 1,275 (196)

Metabolism of Epoxidised Withanolides by a Generalist and a Specialist Insect Species

ChemistryOpen, Volume 14, Issue 12, December 2025.
Larvae of Heliothis (Chloridea) virescence and subflexa have the ability to convert the epoxidized terpenoid 4β‐hydroxywithanolide E (4BHWE) to withanolide S. The conversion is found by feeding the larvae an artificial diet supplemented with 13C‐labeled 4BHWE.
Marie Pauline Sell, Christian Paetz, Felix Feistel, David G. Heckel, Yannick Pauchet   +4 more
wiley   +1 more source

Drug Candidate BIO101 for Spinal Muscular Atrophy as Monotherapy or Combined With the Antisense Oligonucleotide ASO‐10‐27

Journal of Cachexia, Sarcopenia and Muscle, Volume 16, Issue 5, October 2025.
ABSTRACT Background Spinal muscular atrophy (SMA) is a neuromuscular disease caused by loss of survival of motor neuron (SMN) protein inducing progressive muscle weakness and atrophy due to motor neurons degeneration. Despite benefits of SMN restoration therapies in patients, motor defects are still persistent.
Cynthia Bézier, Steve Cottin, Parvin Nazari Hashemi, Mirella El Khoury, Zoé Clerc, Christine Balducci, Delphine Sapaly, Laure Weill, René Lafont, Stanislas Veillet, Pierre J. Dilda, Frédéric Charbonnier, Mathilde Latil, Olivier Biondi   +13 more
wiley   +1 more source

Ethnomedicinal Uses, Phytochemistry, Pharmacological Activities, and Toxicology of the Subfamily Gomphrenoideae (Amaranthaceae): A Comprehensive Review

Chemistry &Biodiversity, Volume 22, Issue 9, September 2025.
ABSTRACT The subfamily Gomphrenoideae is composed of about 480 accepted species, many of which have been historically used as medicinal plants, reason why they have been studied in terms of chemical profile, biological activity, and safety. This review consolidates the advances in research on this subfamily over the past 47 years, emphasizing its ...
Dayanna Isabel Araque Gelves, Giulia Cristina de Andreoli Souza, Alvaro Jose Hernandez Tasco, Marcos José Salvador   +3 more
wiley   +1 more source

Functional Components and Anti-Nutritional Factors in Gluten-Free Grains: A Focus on Quinoa Seeds

Foods, 2021
Quinoa (Chenopodium quinoa Willd.) has recently received increasing interest from both scientists and consumers due to its suitability in gluten-free diets, its sustainability, and its claimed superfood qualities.
Valentina Melini, Francesca Melini
doaj   +1 more source

Food‐Derived Bioactive Peptides With Anti‐Diabetic and Antimicrobial Potential: An Updated Review on Current Trends and Challenges

Sustainable Food Proteins, Volume 3, Issue 2, June 2025.
Food‐derived bioactive peptides with anti‐diabetic and antimicrobial potential: An updated review on current trends and challenges. ABSTRACT The exploration of bioactive peptides derived from diverse food sources demonstrates their potential to provide advantages beyond basic nutrition, such as immunological support, antibacterial activities, and ...
Prashantkumar Natubhai Padhiyar, Brij Pal Singh, Preetam Sarkar, Subrota Hati   +3 more
wiley   +1 more source

Phytochemical Analysis and Anti‐inflammatory Potential of Floscopa Scandens Lour. and Exploring Ecdysterone as Promising Therapeutic Agent: An HR‐LCMS Screening and Molecular Docking Analysis

ChemistrySelect, Volume 9, Issue 40, October 25, 2024.
This study analyzed the bioactive compounds of Floscopa scandens Lour. using HR‐LCMS, isolating 21 phytoconstituents, including ecdysterone as the prominent. Molecular docking and molecular dynamic simulations revealed ecdysterone's anti‐inflammatory potential, confirming its therapeutic significance.
Sailaja Nambaaru, Preeti Nanda Sahu, Sunitha Katta, Veera Raghava Sarma Ganapavarapu, Bhanukiran Kancharla, Anik Sen   +5 more
wiley   +1 more source

Systemic effects of phytoecdysteroids on the cabbage aphid Brevicoryne brassicae (Sternorrhyncha: Aphididae)

European Journal of Entomology, 2005
The systemic effects of phytoecdysteroids were investigated by applying tested compounds to the roots of the rape plants. Evaluation of the effects was based on mortality, longevity, rate of development and fecundity of the cabbage aphid (Brevicoryne ...
Roman PAVELA, Juraj HARMATHA, Martin BÁRNET, Karel VOKÁČ   +3 more
doaj   +1 more source

Beyond boundaries: Neuroprotective effects of steroids and ecdysteroids in SH‐SY5Y cells ‐ A systematic review

Neuroprotection, Volume 2, Issue 2, Page 151-166, June 2024.
This systematic review provides valuable insights into the neuroprotective and antioxidant effects of steroids and ecdysteroids on the human neuroblastoma SH‐SY5Y cells, highlighting their potential as therapeutic agents for neurodegenerative disorders characterized by oxidative stress.
Bizhar Ahmed Tayeb, Isaac Kinyua Njangiru, Renáta Minorics   +2 more
wiley   +1 more source

Phytoecdysteroids: Chemical Structure And Biological Activity

Eurasian journal of applied biotechnology, 2021
Owing to the need to develop new medicines and biologically active food additives with adaptogenic effects, phytoecdysteroids – polyhydroxylated sterols-are of great interest. Different types of drugs, extracts and individual compounds, have a wide range
Zh. S. Akhmetkarimova, B. S. Temirgaziev
semanticscholar   +1 more source

Diversity of Secondary Metabolites in the Genus Silene L. (Caryophyllaceae)—Structures, Distribution, and Biological Properties

Diversity, 2014
The genus Silene (family Caryophyllaceae) comprises more than 700 species, which are widely distributed in temperate zones of the Northern Hemisphere, but are also present in Africa and have been introduced in other continents.
Nilufar Z. Mamadalieva, Rene Lafont, Michael Wink   +2 more
doaj   +1 more source