Results 41 to 50 of about 9,722 (204)

Natural Products as Modulators of ABC Transporters in Breast Cancer

open access: yesPhytotherapy Research, EarlyView.
ABSTRACT Breast cancer remains a significant global health challenge, with high incidence and mortality rates despite advancements in early detection and treatment. Multidrug resistance (MDR), particularly in aggressive subtypes like triple‐negative breast cancer (TNBC), continues to hinder effective therapy.
Yoganishalini Sagadevan   +2 more
wiley   +1 more source

Acute and sub-chronic toxicity of Cajanus cajan leaf extracts

open access: yesPharmaceutical Biology, 2017
Context: The leaves of Cajanus cajan (L.) Millsp. (Fabaceae) have diverse bioactivities, but little safety data are reported. Objective: This study examines the toxicological profiles of C. cajan leaf extracts.
Rong Tang   +5 more
doaj   +1 more source

Cocktails of Mycotoxins, Phytoestrogens, and Other Secondary Metabolites in Diets of Dairy Cows in Austria: Inferences from Diet Composition and Geo-Climatic Factors

open access: yesToxins, 2022
Dairy production is a pivotal economic sector of Austrian and European agriculture. Dietary toxins and endocrine disruptors of natural origin such as mycotoxins and phytoestrogens can affect animal health, reproduction, and productivity.
Felipe Penagos-Tabares   +9 more
doaj   +1 more source

Phytoestrogens in osteoporosis

open access: yesWiadomości Lekarskie
This article explores the role of phytoestrogens in the prevention and treatment of osteoporosis, focusing on soy isoflavones, red clover, and other plants such as Epimedium, hops, fennel, and prunes. It reviews clinical trials examining the effects of these phytoestrogens on bone mineral density (BMD), bone turnover markers, and osteoporotic fracture ...
Mateusz Kaczmarski   +9 more
openaire   +3 more sources

Synthesis of 7,2′-Dihydroxy-4′,5′-Dimethoxyisoflavanone, a Phytoestrogen with Derma Papilla Cell Proliferative Activity

open access: yesMolecules, 2022
This paper reports a concise and scalable method for the synthesis of the phytoestrogen 7,2′-dihydroxy-4′,5′-dimethoxyisoflavanone 1 via an optimized synthetic route.
Taewoo Kim   +6 more
doaj   +1 more source

HUBUNGAN KONSUMSI KACANG-KACANGAN (SUMBER PHYTOESTROGEN) DENGAN USIA MENOPAUSE

open access: yes, 2012
PHYTOESTROGEN CONSUMPTION AND MENOPAUSEBackground: Health development increase the life expectancy age on women. The life expectancy on women in 1980 was 50.9 years, which was Increase to 62.7 years in 1995.
Harahap, Heryudarini   +6 more
core   +1 more source

Phytoestrogen-containing diets offer benefits for mouse embryology but lead to fewer offspring being produced.

open access: yes, 2020
One of the most commonly used protein sources in rodent diets is soy, which is naturally rich in phytoestrogens. Although phytoestrogens have shown potential health benefits in humans, they may also have the ability to disrupt reproduction. Consequently,
Zierau, O., Helppi, J., Naumann, R.
core   +1 more source

Flavonoids in Nasal Therapeutics: Biological Activities, Delivery Challenges, and Formulation Strategies–A Systematic Review

open access: yesPhytotherapy Research, EarlyView.
Overview of the therapeutic potential of flavonoids in nasal delivery systems, highlighting their benefits to the human nasal cavity, and applications in the treatment of respiratory and brain‐related diseases. ABSTRACT Flavonoids represent a significant group of secondary metabolites.
Jeniffer Viviana Ramirez Hernández   +5 more
wiley   +1 more source

Lifestyle Management in Menopause: A Systematic Review of Women With Premature Ovarian Insufficiency

open access: yesClinical Endocrinology, EarlyView.
ABSTRACT Objective Premature ovarian insufficiency (POI), the loss of ovarian function before age 40, increases the risk of cardiovascular disease, low bone mineral density, dementia and psychological distress. Lifestyle interventions reduce chronic disease risk in other populations and, with hormone therapy, may improve health outcomes in POI.
Ladan Yeganeh   +4 more
wiley   +1 more source

Resistance‐exercise‐induced stress intervenes in TGF‐β signaling by cooperatively downregulating nuclear αB‐crystallin and SMAD4 in human skeletal muscle fibers

open access: yesThe FEBS Journal, EarlyView.
Alpha‐crystallin B chain (CRYAB) has been reported to stabilize mothers against decapentaplegic homolog 4 (SMAD4) in transforming growth factor‐β (TGF‐β) signaling, enabling target gene transcription. We show nuclear CRYAB–SMAD4 interaction for the first time in human skeletal muscle fibers and its regulation by exercise.
Kirill Schaaf   +7 more
wiley   +1 more source

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