Results 31 to 40 of about 10,702 (161)

Herbal Therapeutics in Osteoporosis: Mechanisms, Evidence, and Translational Potential

Phytotherapy Research, EarlyView.
Schematic overview of bone remodeling dysregulation in osteoporosis and the multi‐target protective role of herbal therapeutics. ABSTRACT Osteoporosis is a chronic bone disease marked by reduced density and increased fracture risk. Current treatments face limitations in safety, efficacy, and long‐term adherence, prompting interest in alternative ...
Elnaz Vafadar Moradi, Sina Vossoughinia, Zahra Yazdanpanah, Hossein Sobhani, Jalileh Jalali, Mahboobeh Ghasemzadeh Rahbardar   +5 more
wiley   +1 more source

Dietary Phytoestrogen Increases Tumour Size and the Frequency of Circulating Tregs in a B16-F10 Murine Melanoma Tumour Model

Diyala Journal of Medicine
Background: Clinical studies show strong associations between hormone levels, particularly estrogens and the development of skin cancers. Cutaneous melanoma is considered a hormone-related tumour; however, their role in melanoma progression remains ...
Rafah Oday Hussian, Lee Richard Machado
doaj   +1 more source

Synthesis of 7,2′-Dihydroxy-4′,5′-Dimethoxyisoflavanone, a Phytoestrogen with Derma Papilla Cell Proliferative Activity

Molecules, 2022
This paper reports a concise and scalable method for the synthesis of the phytoestrogen 7,2′-dihydroxy-4′,5′-dimethoxyisoflavanone 1 via an optimized synthetic route.
Taewoo Kim, Hyun Su Kim, Jaebong Jang, Dong-Jun Kim, Jongkook Lee, Dongjoo Lee, Seok-Ho Kim   +6 more
doaj   +1 more source

Lifestyle Management in Menopause: A Systematic Review of Women With Premature Ovarian Insufficiency

Clinical Endocrinology, EarlyView.
ABSTRACT Objective Premature ovarian insufficiency (POI), the loss of ovarian function before age 40, increases the risk of cardiovascular disease, low bone mineral density, dementia and psychological distress. Lifestyle interventions reduce chronic disease risk in other populations and, with hormone therapy, may improve health outcomes in POI.
Ladan Yeganeh, Nathalie Vermeulen, Carolyn Ee, Helena Teede, Amanda J. Vincent   +4 more
wiley   +1 more source

Acute and sub-chronic toxicity of Cajanus cajan leaf extracts

Pharmaceutical Biology, 2017
Context: The leaves of Cajanus cajan (L.) Millsp. (Fabaceae) have diverse bioactivities, but little safety data are reported. Objective: This study examines the toxicological profiles of C. cajan leaf extracts.
Rong Tang, Ru-hua Tian, Jia-zhong Cai, Jun-hui Wu, Xiao-ling Shen, Ying-jie Hu   +5 more
doaj   +1 more source

Converting Equol Nonproducers to Producers: A Systematic Review of Randomized Clinical Trials

Food Science &Nutrition, Volume 14, Issue 10, October 2026.
This systematic review, following PRISMA guidelines, screened 503 records identified through PubMed, Embase, Web of Science, and ClinicalTrials.gov, of which 12 randomized clinical trials (n = 730, 85.5% female) met inclusion criteria. Interventions included soy isoflavones alone, probiotics, or prebiotics combined with soy, fermented soy products ...
Jiatong Li, Mengyi Li, Saied Aboushanab, Mark Ebeid, Rieko Hatanaka, Miho Iida, Masato Takase, Ian Jacobs, Arnur Gusmanov, Aya Hirata, Naoko Miyagawa, Naoki Nakaya, Daisuke Sugiyama, Curtis Tilves, Atsushi Hozawa, Xingnan Li, Noel T. Mueller, Panayiotis V. Benos, Akira Sekikawa   +18 more
wiley   +1 more source

Dataset of transcriptomic changes induced by naringenin treatment in MCF-7 breast cancer cellsGene Expression Omnibus

Data in Brief
Naringenin (Nar) is a citrus fruit-derived phytoestrogen, a group of dietary compounds produced by a wide variety of plants. Due to structural similarity to 17‐β‐estradiol (E2), phytoestrogens can bind to estrogen receptors (ERs) to exert context ...
Van T. Hoang, Mackenzie L. Hawes, Jack R. Elliott, Steven Elliott, Binghao Zou, Stephen M. Boué, Brian G. Rowan, Bridgette M. Collins-Burow, Jorge A. Belgodere, Muralidharan Anbalagan, Elizabeth C. Martin, Matthew E. Burow   +11 more
doaj   +1 more source

Hormone therapy (HT) in women with premature ovarian insufficiency or early menopause: Time to think of a new paradigm for healthy aging. A joint FIGO and IMS position paper

International Journal of Gynecology &Obstetrics, Volume 175, Issue 1, Page 26-47, October 2026.
Abstract Premature ovarian insufficiency (POI) and early menopause (EM) affect millions of women worldwide. Compared with normal menopause, they confer a longer duration of estrogen deficiency and are associated not only with a shorter lifespan, but with a reduced healthspan, owing to an increased risk of cardiovascular, skeletal, cognitive and ...
Chiara Benedetto, Suvarna S. Khadilkar, Rossella E. Nappi, Andrea R. Genazzani, Federica Frezet, Laura Cucinella, Hema Divakar, Panagiotis Anagnostis, Nick Panay   +8 more
wiley   +1 more source

Phytoestrogen 23-24 #2

Phytoestrogens have a similar chemical structure to estrogen and can bind the estrogen receptor β. Thus, they have been investigated as potential anti-proliferative therapies in treating estrogen-responsive cancers.
Cenkollari, Vanessa, Aspinwall, Sarah, Touglo, Komlavi   +2 more
core   +3 more sources

Phytoestrogen Project

, 2013
Promensil is an over the counter plant based hormonal supplement used to treat menopausal symptoms, and is considered safer than human estrogen treatments.
Bemis, Randal Glendon, Sejour, Leinal A.
core   +3 more sources