Results 51 to 60 of about 7,375 (146)

Mechanism of Rapid Nuclear Factor-E2-Related Factor 2 (Nrf2) Activation via Membrane-Associated Estrogen Receptors: Roles of NADPH Oxidase 1, Neutral Sphingomyelinase 2 and Epidermal Growth Factor Receptor (EGFR)

Antioxidants, 2019
Membrane-associated estrogen receptors (ER)-α36 and G protein-coupled estrogen receptor (GPER) play important roles in the estrogen’s rapid non-genomic actions including stimulation of cell proliferation.
Tetsuro Ishii, Eiji Warabi
doaj   +1 more source

Nutritional and Health Potential of Edible Seeds: Micronutrient Bioavailability and Mechanistic Insights

Food Science &Nutrition, Volume 14, Issue 2, February 2026.
Their bioactive constituents act through antioxidant, anti‐inflammatory, and metabolic‐regulating mechanisms, validating their classification as functional foods. Evidence from clinical and biochemical studies largely supports these benefits, although some claims stem from preliminary or in vitro findings.
Nighat Raza, Alina Sadaf, Reeha Mushtaq, Mirza Abid Mehmood, Luqman Amrao, Fakhar Islam, Muhammad Afzaal, Mohd Asif Shah   +7 more
wiley   +1 more source

Anticancer Molecular Mechanisms of Phytosterols: An Updated Review on Clinical Trials

Food Science &Nutrition, Volume 14, Issue 2, February 2026.
Phytosterols, a form of naturally occurring substance structurally related to cholesterol, have been getting considerable interest due to their possible anticancer properties. Phytosterols induce apoptosis, block the cell cycle, and abrogate the invasion and metastasis of cancer cells, offering a multi‐manifestation treatment of cancer.
Muhammad Shahbaz, Ushna Momal, Asfa Perween, Hammad Naeem, Muzzamal Hussain, Muhammad Imran, Gamal A. Mohamed, Sabrin R. M. Ibrahim, Suliman A. Alsagaby, Waleed Al Abdulmonem, Entessar Al Jbawi, Mohamed A. Abdelgawad, Samy Selim, Soad K. Al Jaouni, Hagar M. Mohamed   +14 more
wiley   +1 more source

Neurorestoration of Sustained Attention in a Model of HIV-1 Associated Neurocognitive Disorders

Frontiers in Behavioral Neuroscience, 2019
Due to the sustained prevalence of human immunodeficiency virus (HIV)-1 associated neurocognitive disorders (HAND) in the post-combination antiretroviral therapy (cART) era, as well as the increased prevalence of older HIV-1 seropositive individuals ...
Landhing M. Moran, Kristen A. McLaurin, Rosemarie M. Booze, Charles F. Mactutus   +3 more
doaj   +1 more source

Research Progress in the Treatment of Vaginitis With Bioactive Compounds: Targeting of Vaginal Microflora

MicrobiologyOpen, Volume 15, Issue 1, February 2026.
Mechanism diagram of the effect of herbal medicine on vaginitis. Herbal medicines mainly combat vaginitis by (A) inhibiting bacteria, (B) inhibiting fungi, (C) acting on the cilia of Trichomonas, (D) inhibiting virus replication, (E) repairing the mucosa, (F) enhancing immunity, and (G) maintaining the microecological balance.
Yongming Li, Huiyu Liu, Ruihan Li, Rong Li, Jiaqi Liu   +4 more
wiley   +1 more source

Dietary Phytoestrogen Intake is Inversely Associated with Hypertension in a Cohort of Adults Living in the Mediterranean Area

Molecules, 2018
Background: Dietary polyphenols, including phytoestrogens are abundantly present in a balanced diet. Evidence for their role in preventing non-communicable diseases is emerging.
Justyna Godos, Sonia Bergante, Angela Satriano, Francesca Romana Pluchinotta, Marina Marranzano   +4 more
doaj   +1 more source

Immunomodulatory Mechanism of Baiyaojian Decoction on Periodontitis: Network Pharmacology, Single‐Cell RNA Sequencing and Molecular Docking

Journal of Cellular and Molecular Medicine, Volume 30, Issue 3, February 2026.
ABSTRACT Periodontitis is one of the most common oral inflammatory diseases. Baiyaojian decoction, known for its prominent immunomodulatory and anti‐inflammatory properties, shows significant potential in treating periodontitis, though its molecular mechanisms remain unknown. The active ingredients and therapeutic targets were determined by integrating
Bing‐jun Chen, Ming‐ming Li, Zhao‐yu Zheng, Wen‐qin Jin, Zhao Jin, Yu‐ling Zuo   +5 more
wiley   +1 more source

Steroid Hormones Are Potent and Putatively Endogenous Activators of Human Bitter Taste Receptors

Annals of the New York Academy of Sciences, Volume 1556, Issue 1, February 2026.
Human bitter taste receptors are not only involved in sensing tastants within the oral cavity but also play crucial roles in internal tissues of the body. The current report identifies numerous structurally and functionally diverse steroid hormones as activators of the two human bitter taste receptors, TAS2R14 and TAS2R46.
Tatjana Lang, Francesco Ferri, Florian Ziegler, Antonella Di Pizio, Maik Behrens   +4 more
wiley   +1 more source

Association between maternal dietary isoflavone consumption during pregnancy and childhood food allergy in offspring: The Japan Environment and Children's study

Pediatric Allergy and Immunology, Volume 37, Issue 2, February 2026.
Abstract Background Isoflavone (ISO) consumption during pregnancy may affect food allergy (FA) in offspring through estrogen‐like and other biological effects; however, this ISO–FA association in mother–child pairs remains elusive. Herein, the maternal ISO–childhood FA association was investigated using the Japanese birth cohort data.
Gui Yang, Aya Hisada, Midori Yamamoto, Rieko Takatani, Yuki Konno, Naoki Shimojo, Kenichi Sakurai, The Japan Environment and Children's Study (JECS) Group, Michihiro Kamijima, Shin Yamazaki, Maki Fukami, Reiko Kishi, Chiharu Ota, Koichi Hashimoto, Chiharu Ota, Chisato Mori, Shuichi Ito, Ryoji Shinohara, Hidekuni Inadera, Takeo Nakayama, Ryo Kawasaki, Yasuhiro Takeshima, Seiji Kageyama, Narufumi Suganuma, Shoichi Ohga, Takahiko Katoh   +25 more
wiley   +1 more source

Intake of Phytoestrogens and Estrogenic Effect of the Diet of Female University Students in Mexico

Applied Sciences
Phytoestrogens are components naturally occurring in plants and include many foods that are part of the regular diet of animals and humans. Phytoestrogens are xenoestrogens of plant origin that are not produced in the endocrine system. Phytoestrogens can
Diana Espino-Rosales, Leticia Heras-Gonzalez, Maria J. Jimenez-Casquet, Nicolás Olea, Fátima Olea-Serrano, Miguel Mariscal-Arcas   +5 more
doaj   +1 more source