Results 131 to 140 of about 78,385 (260)

Dual Antiviral and Immunomodulatory Effects of Phytochemicals in Influenza A Virus Infection: Targeting Key Host Signaling Pathways

MicrobiologyOpen, Volume 15, Issue 5, October 2026.
Influenza A virus modulates host innate immune pathways, including TLR, RIG‐I, MAPK, and NF‐κB signaling, to support replication and drive inflammatory pathology. Plant‐derived phytocompounds target these interconnected pathways, offering a potential host‐directed immunomodulatory approach complementary to conventional antivirals.
Dibakar Chowdhury, Hillary A. Vanderven, Phurpa Wangchuk, Subir Sarker   +3 more
wiley   +1 more source

Polyphenol‐Rich Foods as a Healthy and Sustainable Strategy: Mental Health and Metabolomic Profiling

Molecular Nutrition &Food Research, Volume 70, Issue 19, 15 October 2026.
A 12‐week nutritional intervention with cocoa flavanols and red‐berry anthocyanins in older adults improved emotional well‐being and identified metabolomic signatures associated with the intervention through urinary metabolome profiling. ABSTRACT The so‑called demographic transition has increased the prevalence of chronic diseases in adults over 65 ...
María Lucía Gómez Nieto, Verónica Puertas‐Martín, Susana Chamorro, Antonio Méndez‐Guerrero, Inmaculada Álvarez‐Acero, Claudia Balderas, Sonia de Pascual‐Teresa   +6 more
wiley   +1 more source

Elucidating the MultiPathway Therapeutic Potential of Trichosanthes kirilowii Bioactives in Intestinal Obstruction via Network Pharmacology and Molecular Dynamics

ChemistryOpen, Volume 15, Issue 10, October 2026.
Network pharmacology identifies 31 shared targets linking T. kirilowii bioactives to intestinal obstruction, highlighting TNF, PI3K‐Akt, and MAPK signaling. Comparative docking, validation, and 100 ns molecular dynamics with MM/GBSA nominate β‐D‐glucopyranosyl‐α‐spinasterol as the leading candidate, binding albumin with the strongest predicted affinity
Tianying Wu, Xiaofen Lin, Wencong Lin, Lixia Huang, Yuewu Lin   +4 more
wiley   +1 more source

β‐sitosterol Alleviates Pulmonary Arterial Hypertension in Rats With Involvement of the VEGF/PI3K/AKT Signaling Pathway

Pulmonary Circulation, Volume 16, Issue 4, October 2026.
ABSTRACT Pulmonary arterial hypertension (PAH) is a progressive and lethal disorder with limited therapeutic options. β‐sitosterol, a plant compound, has shown potential in managing PAH, but its protective mechanisms remain unclear. We evaluated the protective effects of β‐sitosterol against monocrotaline (MCT)‐induced PAH in rats and explored the ...
Xiaobing Wu, Chen Gong, Zhiyu Zeng
wiley   +1 more source

Implication of Oxysterols and Phytosterols in Aging and Human Diseases

Cholesterol is easily oxidized and can be transformed into numerous oxidation products, among which oxysterols. Phytosterols are plant sterols related to cholesterol.
Vigne, Solenne, Pot, Caroline
core   +1 more source

Research progress on physicochemical properties， functions， and application of phytosterols in aquatic animals

Siliao yanjiu
Phytosterols are a type of natural compounds, also known as plant sterols, existing mainly in the forms of free sterols, sterol glycosides, and steryl esters.
FENG Rui, SUN Cunxin, ZHAO Yongfeng
doaj  

Volatile compounds formed during heating of asymmetric distigmasterol-modified acylglycerols as indicators of thermo-oxidative degradation

Scientific Reports
Phytosterols play a significant role for organisms. They are a component of cell membranes and also have transport functions. They are also important for lower human blood cholesterol levels.
Anna Grygier, Magdalena Rudzińska, Dominik Kmiecik, Aleksandra Grudniewska   +3 more
doaj   +1 more source

Efficient Synthesis of Steroidal Intermediates with a C17 Side Chain from Phytosterols by Genetically Modified Mycolicibacterium neoaurum NRRL B‐3805 Strain

ChemistryOpen
22‐Hydroxy‐23,24‐bisnorchol‐4‐ene‐3‐one (4‐HBC) and 3‐oxo‐4,17‐pregnadiene‐20‐carboxylic acid methyl ester (PDCE) are useful precursors for the synthesis of steroidal active pharmaceutical ingredients.
Xuemei Li, Liangyan Zhu, Qiong Wu, Rui Zhang, Yiyin Liu, Na Liu, Jinhui Feng, Qiaqing Wu, Dunming Zhu   +8 more
doaj   +1 more source

APPLICABILITY OF PHYTOSTEROLS ON HYPERCHOLESTEROLEMIA - PRELIMINARY STUDY IN HEALTHY DOGS

, 2017
Purpose: Phytosterols are extracted from some vegetables and cereals with high lipid content and are used as lipid-lowering agents in the prevention of obesity and cardiovascular diseases in people.
Crivellenti, Leandro Zuccolotto, Costa, Paula Barbosa, Rezende, Luara Rodrigues, Oliveira, Frederico Rocha, Crivellenti, Sofia Borin   +4 more
core   +1 more source

Determination of Phytosterols in Corn Products using HPLC/ELSD

, 2004
Phytosterols, which are the sterols occurring in plants, iv are considered to be beneficial for health. They have different forms: free phytosterols and phytosterol esters. It 1 s possible that these different phytosterols may function in different ways.
Zhang, Zhiling
core   +1 more source