Results 71 to 80 of about 724,503 (248)

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Spatial and Temporal Dynamics of Inorganic Phosphate and Adenosine-5′-Triphosphate in the North Pacific Ocean

Frontiers in Marine Science, 2018
Temporal variability in dissolved inorganic, organic phosphate (Pi, DOP) and particulate phosphorus (PPO4) concentrations, and microbial utilization of Pi and dissolved adenosine-5′-triphosphate (DATP) was studied at Station ALOHA (22.75°N, 158°W) in the
Karin M. Björkman, Solange Duhamel, Matthew J. Church, David M. Karl   +3 more
doaj   +1 more source

K(π, 1) arrangements

Topology, 1995
The paper is mainly devoted to the topological theory of arrangements. An \(l\)-arrangement \(A\) is a finite set of hyperplanes in \(C^ l\), and its complement \(C = C(A)\) is the open \(2l\)-manifold \(C^ l \smallsetminus \bigcup A\). If the defining linear forms have real coefficients, then \(A\) is said to be complexified, and the arrangement \(A_ ...
openaire   +2 more sources

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Early Pupil Abnormality Frequency Predicts Poor Outcomes and Enhances International Mission for Prognosis and Analysis of Clinical Trials in Traumatic Brain Injury (IMPACT) Model Prognostication in Traumatic Brain Injury

Critical Care Explorations
IMPORTANCE:. In patients with traumatic brain injury (TBI), baseline pupillary assessment is routine; however, the occurrence rate and clinical significance of pupil abnormalities over the early course of hospitalization remain poorly characterized ...
Divya Veerapaneni, MD, Naveen Arunachalam Sakthiyendran, BS, Yili Du, MS, Leigh Ann Mallinger, BS, Allyson Reinert, BS, So Yeon Kim, MPH, Chuong Nguyen, BS, Ali Daneshmand, MD, MPH, Mohamad Abdalkader, MD, Shariq Mohammed, PhD, Josée Dupuis, PhD, Kevin N. Sheth, MD, Emily J. Gilmore, MD, David Greer, MD, MA, Charlene J. Ong, MD, MPHS   +14 more
doaj   +1 more source

Sistem Presensi Mahasiswa Berbasis RFID Menggunakan Raspberry Pi 1 [PDF]

Jurnal Ilmiah Teknik Elektro Komputer dan Informatika, 2016
Sistem presensi mahasiswa saat ini masih banyak dilakukan dengan penandatanganan lembar kehadiran secara manual. Hal ini tentu saja dinilai lambat dan kurang efisien, baik dari segi waktu maupun proses pengolahan datanya. Presensi manual juga dapat menimbulkan gangguan dan memecah konsentrasi mahasiswa saat melaksanakan perkuliahan.
openaire   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

FEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil, Jeffrey A. Hawkes, Cecilia Blikstad, Pia Lindberg   +3 more
wiley   +1 more source