Results 91 to 100 of about 880,343 (275)
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
Algorithms, 2018 A k-colouring of a graph G with colours 1 , 2 , … , k is canonical with respect to an ordering π = v 1 , v 2 , … , v n of the vertices of G if adjacent vertices are assigned different colours and, for 1 ≤ c ≤ k
Ruth Haas, Gary MacGillivray
doaj +1 more source
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Life of Pi: Exploring functions of Pi16+ fibroblasts [version 2; peer review: 2 approved]
F1000ResearchFibroblasts are mesenchymal cells that are responsible for creating and maintaining tissue architecture through the production of extracellular matrix. These cells also play critical roles in processes such as wound repair and immune modulation in normal
Yein Chung +2 more
doaj +1 more source
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
European Physical Journal C: Particles and FieldsThe departure of the latest FNAL experimental average for the muon anomalous magnetic moment $$a_\mu =(g_\mu -2)/2$$ a μ = ( g μ - 2 ) / 2 measurements, having increased from $$4.2 \sigma $$ 4.2 σ (Abi et al. in Measurement of the positive muon anomalous
M. Benayoun, L. DelBuono, F. Jegerlehner
doaj +1 more source
Low-energy excitations around (\pi/2, \pi/2) points in the pseudogap phase of Nd_1.85Ce_0.15CuO_4
, 2003 Polarized electronic Raman scattering from the NCCO superconductor at optimal electron doping (T_c=22 K) reveals the formation of an anisotropic pseudogap below a characteristic temperature T* ~ 220 K and energy E*_g = 850 cm-1. Below T* a pronounced suppression of the incoherent spectral weight below E*_g in the nodal directions of k-space is observed.
Koitzsch, A. +5 more
openaire +1 more source
Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source