Results 71 to 80 of about 442,345 (289)

PI-RADS score v.2 in predicting malignancy in patients undergoing 5α-reductase inhibitor therapy

, 2021
Background To investigate if the PI-RADS score represents an effective tool in detecting prostate cancer in patients treated with a 5 alpha-reductase inhibitor (dutasteride) and to identify dedicated total serum PSA and PSA density thresholds.
R. Bertolo, Ciccariello, M, V. de Soccio, M. Sperandio, Bertolo, R, P. Bove, M. Ciccariello, Cavallo, A U, de Soccio, V, Bove, P, Forte, V, A. U. Cavallo, Sperandio, M, V. Forte   +13 more
core   +1 more source

Mdprostate AI and radiologist performance and interobserver agreement using bpMRI to predict the likelihood of prostate cancer based on PI-RADS

Journal of the Mexican Federation of Radiology and Imaging
Introduction: Artificial intelligence (AI) has improved the diagnostic performance of prostate magnetic resonance imaging (MRI) and reduced interobserver variability in Prostate Imaging Reporting and Data System (PI-RADS) scores.
Eduardo Valencia-Segura, Beatriz Elias-Perez, Arturo Hernandez-Medina, Francisco J. Omaña-Villagran   +3 more
doaj   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Simplified PI-RADS with Biparametric MRI: A Practical Approach to Improve Management of PI-RADS Version 2 Category 3 Lesions [PDF]

Radiology, 2018
Letter
Scialpi, Michele, Scialpi, Pietro, Aisa, Maria Cristina, Martorana, Eugenio, D’Andrea, Alfredo   +4 more
openaire   +2 more sources

Urine biomarkers can predict prostate cancer and PI-RADS score prior to biopsy. [PDF]

Prostate-Specific Antigen (PSA) based screening of prostate cancer (PCa) needs refinement. The aim of this study was the identification of urinary biomarkers to predict the Prostate Imaging-Reporting and Data System (PI-RADS) score and the presence of ...
Cesson, Valérie, Derré, Laurent, Gu, Alexander, Laurent Derré, Pavlovic, Blaz, Dartiguenave, Florence, Veit, Markus, Valerio, Massimo, Banzola, Irina, Poyet, Cédric, Thomas Hermanns, Cédric Poyet, Paul Martel, Eberli, Daniel, Rakauskas, Arnas, Pascal Oechslin, Alexander Gu, Saba, Karim, Valérie Cesson, Hermanns, Thomas, Florence Dartiguenave, Niels J. Rupp, Andreas M. Hötker, Arnas Rakauskas, Blaz Pavlovic, Konstantin Bräutigam, Hötker, Andreas M, Rupp, Niels J, Daniel Eberli, Oechslin, Pascal, Markus Veit, Martel, Paul, Irina Banzola, Karim Saba, Massimo Valerio, Bräutigam, Konstantin   +35 more
core   +2 more sources

Multicenter Study on Integrating Prostate Magnetic Resonance Imaging with Prostate-Specific Antigen Density for Risk-Adapted Biopsy Strategy in a South Korean Cohort

Urology Research and Practice
Objective: Combining Prostate Imaging-Reporting and Data System (PI-RADS) with prostate-specific antigen density (PSAD) may improve the detection of clinically significant prostate cancer (csPCa) while reducing unnecessary biopsies.
Seung-Ju Lee, Dong Ho Shin, Hee Youn Kim
doaj   +1 more source

Assessing the validity of Prostate Imaging Reporting and Data System version 2 (PI-RADS v2) scoring system in diagnosis of peripheral zone prostate cancer

European Journal of Radiology Open, 2017
The purpose: Assessing the accuracy of multi parametric magnetic resonance (mp-MRI) after application of PI-RADS V2 for diagnosis of prostate cancer as comparison to pathological results of trans rectal ultra-sound (TRUS) guided biopsy.
Eman F. Dola, Osama L. Nakhla, Eman A.SH Genidi   +2 more
doaj   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

Evaluating quantitative dynamic contrast-enhanced MRI as an addition to prostate imaging reporting and data system version 2.1 for prostate cancer detection: a prospective study

Alexandria Journal of Medicine
Background Prostate cancer is a leading malignancy in men, and multiparametric MRI (mpMRI), particularly dynamic contrast-enhanced (DCE)-MRI, plays a key role in identifying and characterizing lesions. While prostate imaging reporting and data system (PI-
Omnia E. Eldin, Amel G. Eldin, Adel A. Ramadan, Ahmed H. Afifi, Khaled Refaai, Ahmed M. Beltagy, Samar El Achy, Omneya Gamaleldin   +7 more
doaj   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source