Results 111 to 120 of about 862,963 (270)
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
A Berezin-type map and a class of weighted composition operators
Concrete Operators, 2017 In this paper we consider the map L defined on the Bergman space La2(+)$L_a^2({{\rm\mathbb{C}}_{\rm{ + }}})$ of the right half plane ℂ+ by (Lf)(w)=πM′(w)∫+(fM′)(s)|bw(s)|2dA˜(s)$(Lf)(w) = \pi M'(w)\int\limits_{{{\rm\mathbb{C}}_{\rm{ + }}}} {\left( {{f \
Das Namita
doaj +1 more source
, 2021 Supplementary table 4. List of 47 Sri Lankan rice accessions deposited in Rice SNP-Seek Database of the International Rice Research ...
Terensan, Suvanthini +5 more
openaire +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
System leadership for school improvement: A developing concept and set of practices [PDF]
, 2016 System'leadership'is'a'developing'concept'and'practice'increasingly'seen'as'a' tool'for' school' improvement,' as' policy'makers' switch'from'traditional'top?down' reform' to' professional' models' of' schools' working' collaboratively.' System ...
Dimmock, Clive
core
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Molecular Plant-Microbe Interactions, 2008 The avirulence (AVR) gene AVR-Pita in Magnaporthe oryzae prevents the fungus from infecting rice cultivars containing the resistance gene Pi-ta. A survey of isolates of the M.
Chang Hyun Khang +4 more
doaj +1 more source
Higher Readmissions at Safety-Net Hospitals and Potential Policy Solutions [PDF]
, 2012 The Hospital Readmissions Reduction Program (HRRP), established by the Affordable Care Act, ties a hospital's payments to its readmission rates -- with penalties for hospitals that exceed a national benchmark -- to encourage hospitals to reduce avoidable
Anthony Shih, Julia Berenson
core
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source