Results 91 to 100 of about 3,793,930 (259)

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Radiative rho(+)->pi(+)gamma decay in light cone QCD

open access: yes, 2001
We investigate the radiative rho (+) --> pi (+)gamma decay in the framework of the light cone QCD sum rules. We estimate the coupling constant gp,, for this decay and using this value of the coupling constant, we calculate the decay width of the rho (+) -
Gokalp, A, Yılmaz, Osman
core  

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

DOES GENERATION Z TRUST INFLUENCERS? EXAMINING THE RELATIONSHIP BETWEEN INFLUENCER CREDIBILITY, ATTITUDE TOWARDS BRAND, WORD-OF-MOUTH AND PURCHASE INTENTION

open access: yesCumhuriyet Üniversitesi İktisadi ve İdari Bilimler Dergisi
The objective of the present study is to investigate the interconnections among influencer credibility, consumer attitudes towards brands endorsed by influencers, word-of-mouth intention (WOMI) regarding these brands, and purchase intention (PI) within ...
İsmail Gökhan Cintamür
doaj   +1 more source

Association of Alpha-1 Antitrypsin Pi*Z Allele Frequency and Progressive Liver Fibrosis in Two Chronic Hepatitis C Cohorts. [PDF]

open access: yesJ Clin Med, 2022
Mücke VT   +12 more
europepmc   +1 more source

Amplitude Analysis of the Decays $\eta^\prime \rightarrow \pi^+\pi^-\pi^0$ and $\eta^\prime \rightarrow \pi^0\pi^0\pi^0$ [PDF]

open access: yes, 2017
Based on a sample of $1.31 \times 10^9$ $J/\psi$ events collected with the BESIII detector, an amplitude analysis of the isospin-violating decays $\eta^\prime \rightarrow \pi^+\pi^-\pi^0$ and $\eta^\prime \rightarrow \pi^0\pi^0\pi^0$ is performed.
Yu, B. X.   +999 more
core   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Home - About - Disclaimer - Privacy