Results 81 to 90 of about 2,909,495 (269)

Pi-WRF 3.0

open access: yes, 2021
This project set out to develop educational modules and activities around running a real weather model on a Raspberry Pi to make a weather forecast.
Reid Olson (11262270)
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Observation of e(+)e(-) -> pi(0)pi(0)h(c) and a Neutral Charmoniumlike Structure Z(c)(4020)(0)

open access: yes, 2014
Using data collected with the BESIII detector operating at the Beijing Electron Positron Collider at center-of-mass energies of root s = 4.23, 4.26, and 4.36 GeV, we observe e(+)e(-) -> pi(0)pi(0)h(c) for the first time.
Albrecht, M.   +52 more
core   +2 more sources

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Staged lateral⁃posterior lumbar interbody fusion for degenerative spinal deformity

open access: yesChinese Journal of Contemporary Neurology and Neurosurgery
Objective To evaluate the efficacy and safety of a staged lateral ⁃ posterior lumbar interbody fusion in the treatment of degenerative spinal deformity (DSD).
LIU Zhen‐lei   +5 more
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Precision measurement of the matrix elements for $\eta\to\pi^+\pi^-\pi^0$ and $\eta\to\pi^0\pi^0\pi^0$ decays

open access: yes, 2023
A precision measurement of the matrix elements for $\eta\to\pi^+\pi^-\pi^0$ and $\eta\to\pi^0\pi^0\pi^0$ decays is performed using a sample of $(10087\pm44)\times10^6$ $J/\psi$ decays collected with the BESIII detector. The decay $J/\psi \to \gamma \eta$
M. Fritsch   +999 more
core   +1 more source

Association of paraspinal muscle morphology or composition with sagittal spinopelvic alignment: a systematic review and meta-analysis

open access: yesBMC Musculoskeletal Disorders
Purpose The aim of this study was to evaluate the association of paraspinal muscle morphology and composition with sagittal spinopelvic alignment (SSA). Methods This review was registered at PROSPERO (CRD42022371879).
Fangda Si   +4 more
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

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