Results 61 to 70 of about 2,909,495 (269)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Reusability of PI-Z. mobilis.

open access: yes, 2013
Fermentation of PI-Z. mobilis was carried out at 30°C and pH 7 for 24 h, with an initial glucose concentration of 100 g/l. At the end of each fermentation run, PI-Z.
Zijian Zhao (484183)   +7 more
core   +1 more source

Corrigendum to “Symplectic and orthogonal $K$-groups of the integers”

open access: yesComptes Rendus. Mathématique
The action of the duality functor on the odd torsion of $K_n(\mathbb{Z})$ was stated incorrectly in [3], in half of the cases, and lead to incorrect formulas for the odd primary torsion of $\pi _nB\mathrm{Sp}(\mathbb{Z})^+$ and $\pi _nBO_{\infty ,\infty }
Schlichting, Marco
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Pi-Pi interaction parameters for each compound and STING residues.

open access: yes, 2019
Pi-Pi interaction parameters for each compound and STING residues.
Xinhui Wang (126681)   +9 more
core   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Characterization of alpha-1 antitrypsin in a Pi∗ZZ patient with emphysema: a case report

open access: yesRespiratory Medicine Case Reports
Background: Lung disease severity and progression vary widely among individuals with severe alpha-1 antitrypsin deficiency (AATD; Pi∗ZZ, Glu342Lys). In addition to low levels of polymerized Z mutant AAT (Z-AAT), this variability may result from other ...
Arturo Olivares Rivera   +6 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Prevalence of Alpha-1 Antitrypsin Deficiency Alleles in a Lithuanian Cohort of Wheezing Small Children

open access: yesAdvances in Respiratory Medicine
Severe inherited alpha-1 antitrypsin deficiency (AATD) is an autosomal genetic condition linked to chronic obstructive pulmonary disease (COPD). The significance of heterozygous, milder deficiency variants (PiSZ, PiMZ, PiMS) is less clear.
Edita Poluzioroviene   +6 more
doaj   +1 more source

Зростання канонічних добутків Вейєрштрасса нульового роду з випадковими нулями

open access: yesKarpatsʹkì Matematičnì Publìkacìï, 2013
Нехай $\zeta=(\zeta_n)$ - комплексна послідовність нульового роду з показником збіжності $\tau$, $N(r)$ - її усереднена лічильна функція, $\pi(z)=\prod\bigl(1-\frac{z}{\zeta_n}\bigr)$ - канонічний добуток Вейєрштрасса, а $M(r)$ - максимум модуля цього ...
Yu.B. Zakharko, P.V. Filevych
doaj   +1 more source

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