Results 61 to 70 of about 3,793,930 (259)
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Corrigendum to “Symplectic and orthogonal $K$-groups of the integers”
The action of the duality functor on the odd torsion of $K_n(\mathbb{Z})$ was stated incorrectly in [3], in half of the cases, and lead to incorrect formulas for the odd primary torsion of $\pi _nB\mathrm{Sp}(\mathbb{Z})^+$ and $\pi _nBO_{\infty ,\infty }
Schlichting, Marco
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Characterization of alpha-1 antitrypsin in a Pi∗ZZ patient with emphysema: a case report
Background: Lung disease severity and progression vary widely among individuals with severe alpha-1 antitrypsin deficiency (AATD; Pi∗ZZ, Glu342Lys). In addition to low levels of polymerized Z mutant AAT (Z-AAT), this variability may result from other ...
Arturo Olivares Rivera +6 more
doaj +1 more source
Зростання канонічних добутків Вейєрштрасса нульового роду з випадковими нулями
Нехай $\zeta=(\zeta_n)$ - комплексна послідовність нульового роду з показником збіжності $\tau$, $N(r)$ - її усереднена лічильна функція, $\pi(z)=\prod\bigl(1-\frac{z}{\zeta_n}\bigr)$ - канонічний добуток Вейєрштрасса, а $M(r)$ - максимум модуля цього ...
Yu.B. Zakharko, P.V. Filevych
doaj +1 more source
Fermentation of PI-Z. mobilis was carried out at 30°C and pH 7 for 24 h, with an initial glucose concentration of 100 g/l. At the end of each fermentation run, PI-Z.
Zijian Zhao (484183) +7 more
core +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Severe inherited alpha-1 antitrypsin deficiency (AATD) is an autosomal genetic condition linked to chronic obstructive pulmonary disease (COPD). The significance of heterozygous, milder deficiency variants (PiSZ, PiMZ, PiMS) is less clear.
Edita Poluzioroviene +6 more
doaj +1 more source
Correlations between the CBF-PI-15, Mini IPIP, BFI-10, and CBF-PI-B.
Correlations between the CBF-PI-15, Mini IPIP, BFI-10, and CBF-PI-B.
Jiaxin Deng (4669423) +4 more
core +1 more source

