Results 61 to 70 of about 3,793,930 (259)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Corrigendum to “Symplectic and orthogonal $K$-groups of the integers”

open access: yesComptes Rendus. Mathématique
The action of the duality functor on the odd torsion of $K_n(\mathbb{Z})$ was stated incorrectly in [3], in half of the cases, and lead to incorrect formulas for the odd primary torsion of $\pi _nB\mathrm{Sp}(\mathbb{Z})^+$ and $\pi _nBO_{\infty ,\infty }
Schlichting, Marco
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Characterization of alpha-1 antitrypsin in a Pi∗ZZ patient with emphysema: a case report

open access: yesRespiratory Medicine Case Reports
Background: Lung disease severity and progression vary widely among individuals with severe alpha-1 antitrypsin deficiency (AATD; Pi∗ZZ, Glu342Lys). In addition to low levels of polymerized Z mutant AAT (Z-AAT), this variability may result from other ...
Arturo Olivares Rivera   +6 more
doaj   +1 more source

Зростання канонічних добутків Вейєрштрасса нульового роду з випадковими нулями

open access: yesKarpatsʹkì Matematičnì Publìkacìï, 2013
Нехай $\zeta=(\zeta_n)$ - комплексна послідовність нульового роду з показником збіжності $\tau$, $N(r)$ - її усереднена лічильна функція, $\pi(z)=\prod\bigl(1-\frac{z}{\zeta_n}\bigr)$ - канонічний добуток Вейєрштрасса, а $M(r)$ - максимум модуля цього ...
Yu.B. Zakharko, P.V. Filevych
doaj   +1 more source

Reusability of PI-Z. mobilis.

open access: yes, 2013
Fermentation of PI-Z. mobilis was carried out at 30°C and pH 7 for 24 h, with an initial glucose concentration of 100 g/l. At the end of each fermentation run, PI-Z.
Zijian Zhao (484183)   +7 more
core   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Prevalence of Alpha-1 Antitrypsin Deficiency Alleles in a Lithuanian Cohort of Wheezing Small Children

open access: yesAdvances in Respiratory Medicine
Severe inherited alpha-1 antitrypsin deficiency (AATD) is an autosomal genetic condition linked to chronic obstructive pulmonary disease (COPD). The significance of heterozygous, milder deficiency variants (PiSZ, PiMZ, PiMS) is less clear.
Edita Poluzioroviene   +6 more
doaj   +1 more source

Correlations between the CBF-PI-15, Mini IPIP, BFI-10, and CBF-PI-B.

open access: yes, 2019
Correlations between the CBF-PI-15, Mini IPIP, BFI-10, and CBF-PI-B.
Jiaxin Deng (4669423)   +4 more
core   +1 more source

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