Results 41 to 50 of about 522,977 (267)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Optimizing voltage control in AC microgrid systems with fuzzy logic strategies and performance assessment

Electrical engineering & Electromechanics
Introduction. Microgrids (MGs) have garnered significant attention for their numerous advantages, providing a solution for powering remote and distant locations while enhancing system reliability.
S. Adiche, M. Larbi, D. Toumi
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Fuzzy Gain-Scheduling PI Controller Design for Large-Scale Wind Turbine

Zhongguo dianli, 2020
When the wind speed exceeds the rated value, usually the blade pitch controller will be put into the operation of large-scale wind turbine. Specifically, the blade pitch angle is adjusted to maintain appropriate angle of attacking on the blade. Thus, the
Gengda LI, Zhongwei LIN, Zhenyu CHEN, Zhenqing DUAN, Baowei CHEN   +4 more
doaj   +1 more source

Optimal PI control parameters for accurate underfloor heating temperature control [PDF]

E3S Web of Conferences, 2019
In low energy buildings, the effect of internal and solar gains on heat balance of rooms is large. As a result, the heating systems, designed assuming steady-state conditions with no heat gains, are over-dimensioned for most of the heating period.
Kull Tuule Mall, Thalfeldt Martin, Kurnitski Jarek   +2 more
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

GPIO-based rail pressure control for diesel high pressure common rail injection system

The Journal of Engineering, 2019
The rail pressure control in diesel high-pressure common rail (HPCR) system is considered as one of the key issues for precise control of fuel injection.
Jiapeng Wang, Hao Sun, Chen Dai, Shihua Li   +3 more
doaj   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source