Results 81 to 90 of about 538,728 (248)

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

On-line Tuning Strategy for PI Control Algorithms

Journal of King Saud University: Engineering Sciences, 1999
On-line model-based tuning of the parameters of conventional PI control algorithms is considered. This is accomplished by requiring satisfaction of the performance specifications.
Emad Ali
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Interplay between the brain and adipose tissue: a metabolic conversation

EMBO Reports
The central nervous system and adipose tissue interact through complex communication. This bidirectional signaling regulates metabolic functions. The hypothalamus, a key homeostatic brain region, integrates exteroceptive and interoceptive signals to ...
Francisco Díaz-Castro, Eugenia Morselli, Marc Claret   +2 more
doaj   +1 more source

Research on Control Strategy of Independent Micro-grid with Photovoltaic Energy Storage

Zhongguo dianli
Regarding the volatility and uncertainties in the operation of independent microgrid with photovoltaic energy storage, a control strategy based on sliding mode is proposed to enhance the robustness against various disturbances and improve the system ...
Jiong CHEN, Wenqing WU, Hao LI, Ziyi QIN, Xiang CHEN, Xuanyuan CHEN   +5 more
doaj   +1 more source

Traffic Light Timer Control Using Raspberry Pi

Aptisi Transactions on Technopreneurship, 2019
As time goes by and the development of the times is very rapid increase in the number of vehicle volumes is increasing from year to year, coupled with automotive manufacturers who release their products at prices below the standard.
Armandio Philip, Cheetah Savana Putri, Putra Maula Arifanggi   +2 more
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

New tuning rules for PI and fractional PI controllers

IFAC Proceedings Volumes, 2009
Abstract Abstract This paper presents new tuning rules for PI and fractional PI control of processes that are typically found in process control. The rules are based on characterization of process dynamics by three parameters that can be obtained from a simple step response experiment.
Juan J. Gude, Evaristo Kahoraho
openaire   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source