Results 71 to 80 of about 143,337 (259)

ZSL Orchestrates Synaptonemal Complex Assembly as a Central Region Scaffold to Ensure Synapsis Fidelity and Crossover Control in Polyploid Meiosis

Advanced Science, EarlyView.
A central molecular adaptor, ZSL, is identified that links transverse filaments ZYP1 to central element SCEP1/2 to drive synaptonemal complex assembly in Brassica napus. Loss of ZSL abolishes synaptonemal complex formation, disrupts meiotic chromosome segregation, and markedly increases crossovers, providing mechanistic insight into meiotic fidelity ...
Miaowei Geng, Shaochen Jia, Fei Cao, Cuiping Liu, Heshuang Zhang, Gang Xu, Jixin Zhuang, Yashi Zhang, Can Liu, Yuhang Zhao, Zilin Guo, Xinjie Yuan, Jiaqing Yang, Lei Chu, Bowei Cai, Hu Zhao, Chao Yang   +16 more
wiley   +1 more source

On Hopkins' Picard group

We compute the algebraic Picard group of the category of $K(n)$-local spectra, for all heights $n$ and all primes $p$. In particular, we show that it is always finitely generated over $\mathbb{Z}_p$ and, whenever $n \geq 2$, is of rank $2$, thereby confirming a prediction made by Hopkins in the early 1990s.
Barthel, Tobias, Schlank, Tomer M., Stapleton, Nathaniel, Weinstein, Jared   +3 more
openaire   +4 more sources

The Basso-Dixon formula and Calabi-Yau geometry

Journal of High Energy Physics
We analyse the family of Calabi-Yau varieties attached to four-point fishnet integrals in two dimensions. We find that the Picard-Fuchs operators for fishnet integrals are exterior powers of the Picard-Fuchs operators for ladder integrals.
Claude Duhr, Albrecht Klemm, Florian Loebbert, Christoph Nega, Franziska Porkert   +4 more
doaj   +1 more source

On the Picard group scheme of the moduli stack of stable pointed curves

, 2020
The aim of the present paper is to study the (abstract) Picard group and the Picard group scheme of the moduli stack of stable pointed curves over an arbitrary scheme.
Fringuelli, Roberto, Viviani, Filippo
core  

Picard groups in p-adic Fourier theory [PDF]

Manuscripta Mathematica, 2013
22 ...
openaire   +2 more sources

DNA Replication Errors Drive Genome‐Wide Small Inverted Triplication Dynamics

Advanced Science, EarlyView.
This study provides insight into the dynamic equilibrium mechanism of a novel structural variant, small inverted triplication (SIT), which is generated by misalignment of the 3’ flap generated under DNA replication stress with palindromic sequence. Alternatively, the end sequence may fold back on itself to form an inverted fragment.
Yi Lei, Yu Zhou, Haitao Sun, Hang Yuan, Xinyu Pei, Jessica D. Hess, Yao Yan, Zunsong Hu, Mian Zhou, Zhaohui Gu, Li Zheng, Xiwei Wu, Binghui Shen   +12 more
wiley   +1 more source

Development and validation of a French questionnaire concerning patients’ perspectives of the quality of palliative care: the QUALI-PALLI-Patient

BMC Palliative Care, 2019
Background Indicators for the quality of palliative care are a priority of caregivers and managers to allow improvement of various care settings and their comparison.
Frédéric Guirimand, Patricia Martel-Samb, Christian Guy-Coichard, Stéphane Picard, Bernard Devalois, Laure Copel, Anne Abel, Véronique Ghadi, QUALI-PALLI group and Philippe Aegerter   +8 more
doaj   +1 more source

SAA/FPR2 Signaling Between Pericentral Hepatocytes and Macrophages Exacerbates Zonated Liver Transplant Injury

Advanced Science, EarlyView.
After liver transplantation, ischemia‐reperfusion injury is more severe in pericentral regions. Multiomic analyses of human grafts and mouse models identify FOXO1 activation in pericentral hepatocytes as an upstream driver of SAA secretion. SAA recruits and activates FPR2+ macrophages, amplifying local inflammation. Amilo‐5MER inhibits SAA bioactivity,
Feng Zhang, Rong Li, Tingting Wang, Jianhao Zhang, Zhengqi Wu, Qiang You, Xuying Liu, Cuicui Xiao, Jiebin Zhang, Haitian Chen, Jiaqi Xiao, Jia Yao, Jun Zheng, Yingcai Zhang, Hua Li, Shuhong Yi, Yang Yang, Qi Zhang, Xiaofeng Yuan, Yasong Liu   +19 more
wiley   +1 more source

Deciphering the Evolution Pattern of Structural Variations Overlapped With Repetitive Sequence During Cattle Evolution

Advanced Science, EarlyView.
The authors complement bovine pan‐SV with massive novel structural variations (SVs) identified through long‐read sequencing of 83 globally distributed cattle breeds. Repetitive sequence‐mediated SVs (rep‐SV) exhibit distinct dynamic patterns throughout cattle sub‐speciation and/or domestication processes, including uneven distribution between chr‐X and
Zhifan Guo, Jinxiu Li, Adeniyi C. Adeola, Xueyan Jiang, Juntao Ma, Jian Xiao, Dexiang Hu, Kaixing Qu, Haihong Wu, Junren Chen, Zhanxing He, Tingting Yin, Ali Esmailizadeh, Jing Luo, Olivier Hanotte, Ya‐Ping Zhang, Yan Li   +16 more
wiley   +1 more source

Multi‐Omics Insights Into the Mechanisms of Early Muscle Fiber Difference and Transformation Between Lean‐Type and Chinese Indigenous Pigs

Advanced Science, EarlyView.
Multi‐omics analyses uncover breed‐specific cis‐regulatory landscapes and higher‐order chromatin architectural differences that underlie early postnatal muscle fiber divergence in pigs. A super‐enhancer upstream of PPP3CB recruits MEF2C to activate PPP3CB transcription, while the PPP3CB–MEF2C positive feedback loop promotes oxidative muscle fiber ...
Shuailong Zheng, Hainan Wu, Min Liu, Kunpeng Wu, Shuntao Huang, Zulfiqar Ahmed, Lenox Pius, Mengjin Zhu, Dequan Xu   +8 more
wiley   +1 more source