Results 101 to 110 of about 6,601 (222)
Molecular architecture of the human protein deacetylase Sirt1 and its regulation by AROS and resveratrol [PDF]
, 2013 Sirtuins are NAD+-dependent protein deacetylases regulating metabolism, stress responses and ageing processes. Among the seven mammalian Sirtuins, Sirt1 is the physiologically best-studied isoform.
Curth, Ute +5 more
core +2 more sources
Advanced Science, Volume 12, Issue 42, November 13, 2025.Engineered neutrophil‐derived vesicles (SOD2‐Fer‐1@CVs) co‐delivering antioxidant and ferroptosis‐inhibitory agents enable inflammation‐targeted, ROS‐responsive therapy for ischemia–reperfusion injury in lung transplantation. Synergizing with ex vivo lung perfusion, this strategy alleviates oxidative stress and inflammation, restores vascular integrity,
Hao‐Xiang Yuan +10 more
wiley +1 more source
In-vitro sulfation of piceatannol by human liver cytosol and recombinant sulfotransferases
Journal of Pharmacy and Pharmacology, 2009 Abstract Objectives The aim of this study was to investigate the concentration-dependent sulfation of piceatannol, a dietary polyphenol present in grapes and wine and known for its promising anticancer and anti-inflammatory activity. Methods
Böhmdorfer, Michaela +4 more
openaire +2 more sources
The Kaohsiung Journal of Medical Sciences, Volume 41, Issue 11, November 2025.ABSTRACT Rhaponitin (Rha) possesses anti‐tumor activity and mediates the transcriptional activity of hypoxia‐inducible factor (HIF)‐1α that affects cisplatin (Cis) resistance. However, whether Rha can lessen Cis resistance in tongue squamous cell carcinoma (TSCC) by mediating HIF‐1α activity is unclear. Cis‐resistant SCC9 (SCC9‐CisR) cells were treated
Yuan Wu +5 more
wiley +1 more source
Parasites & Vectors, 2017 Background Schistosomiasis is one of the most common parasitic diseases affecting millions of humans and animals worldwide. Understanding the signal transduction pathways and the molecular basis of reproductive regulation in schistosomes is critically ...
Han Ding +10 more
doaj +1 more source
パッションフルーツ種子に含まれるポリフェノールPiceatannolに関する機能性研究 [PDF]
, 2018 筑波大学 (University of Tsukuba ...
内田 裕子
core +1 more source
The oxygenase CAO-1 of Neurospora crassa is a resveratrol cleavage enzyme. [PDF]
, 2013 The genome of the ascomycete Neurospora crassa encodes CAO-1 and CAO-2, two members of the carotenoid cleavage oxygenase family that target double bonds in different substrates. Previous studies demonstrated the role of CAO-2 in cleaving the C40 carotene
Al-Babili, Salim +4 more
core +1 more source
Moderate Electric Fields – a processing biotechnological tool [PDF]
, 2015 During the latest decade, much research on Ohmic Heating (OH) as electro-heating technology has been addressed, and the effects of its moderate electric fields (MEF) have been addressed aiming at fighting pathogens and improving the nutritional and ...
Genisheva, Zlatina Asenova +6 more
core
The PGE2-Stat3 interaction in doxorubicin-induced myocardial apoptosis [PDF]
, 2017 Aims Both cyclooxygenase-2 (COX-2) and the transcription factor signal transducer and activator of transcription 3 (Stat3) are involved in adaptive growth and survival of cardiomyocytes. In ventricular cardiomyocytes, prostaglandin E2 (PGE2), a major COX-
Frias, Miguel A. +5 more
core
Piceatannol: A Potential Futuristic Natural Stilbene as Fetal Haemoglobin Inducer
JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH, 2013 Beta thalassaemia is an autosomal recessive inherited blood disorder which results in abnormal formation of Haemoglobin molecule and ineffective erythropoiesis. Patients need to be dependent on habitual blood transfusion and on unaffordable exorbitant therapies for continued existence.
Aayush Kukreja +3 more
openaire +4 more sources