Results 101 to 110 of about 5,057,148 (287)
Caloric restriction reveals a metabolomic and lipidomic signature in liver of male mice [PDF]
, 2014 Lipid composition, particularly membrane unsaturation, has been proposed as being a lifespan determinant, but it is currently unknown whether caloric restriction (CR), an accepted life-extending intervention, affects cellular lipid profiles.
Jové, Mariona +6 more
core +3 more sources
Aging Cell, Volume 24, Issue 9, September 2025.Bifidobacterium pseudocatenulatum NCU‐08, isolated from the feces of centenarians, facilitated the entry of L‐tryptophan into hippocampal neurons of SAMP8 mice, where it was metabolized into NAD+. The increased NAD+ levels activated Sirt1 protein, thereby suppressing the expression of senescence‐associated proteins P53, P21, and Rb, ultimately delaying
Tangchang Xu +8 more
wiley +1 more source
Solid–Solid Synthesis, Crystal Structure and Thermal Decomposition of Copper(II) Complex of 2-Picolinic Acid [PDF]
Iranian Journal of Chemistry & Chemical Engineering, 2016 The copper(II) complex [Cu(pic)2]·2H2O was synthesized with 2-picolinic acid (Hpic) and copper acetate as reactants by room temperature solid-solid reaction.
Di Li, Guo-Qing Zhong, Qing Zang
doaj
Highly sensitive quantification of 7α-hydroxy-4-cholesten-3-one in human serum by LC-ESI-MS/MS
Journal of Lipid Research, 2007 We describe a highly sensitive and specific method for the quantification of serum 7α-hydroxy-4-cholesten-3-one (C4), which has been used as a biomarker for bile acid biosynthesis.
Akira Honda +6 more
doaj +1 more source
Acta Scientiarum: Biological Sciences, 2011 The effect of 2-pyridinecarboxylic acid (picolinic acid) on trypanosomes of the subgenus Schizotrypanum isolated from the bat Phyllostomus hastatus was determined in this study.
Paulo Roberto Ceridóreo Corrêa +5 more
doaj
E-Journal of Chemistry, 2005 The reaction of Co(NO3)2.6H2O and Ni(NO3)2.6H2O with hydrazones derived from 1-phenyl-3-methyl-4-acyl-5-pyrazolone (where acyl = acetyl, propionyl, butyryl and benzoyl) with 2-picolinic acid hydrazide have been studied and characterized on the basis of ...
Chetan K. Modi +2 more
doaj +1 more source
Bulletin of the Chemical Society of Japan, 2019 A CpRu/Bronsted acid-combined catalyst, CpRu(II)/picolinic acid (PyCOOH), acts as an efficient catalyst for the allyl protection/deprotection of alcohols.
Shinji Tanaka +3 more
semanticscholar +1 more source
Comparison of the Plasma Metabolome Profiles Between the Internal Thoracic Artery and Ascending Aorta in Patients Undergoing Coronary Artery Bypass Graft Surgery Using Gas Chromatography Time-of-Flight Mass Spectrometry. [PDF]
, 2019 BackgroundThe left internal thoracic artery (LITA) has been used as the first conduit of choice in coronary artery bypass grafting (CABG) because of excellent long-term patency and outcomes.
Cho, Joo Youn +6 more
core
Copper-catalyzed ortho-C-H amination of protected anilines with secondary amines [PDF]
, 2014 A practical Cu-catalyzed picolinamide-directed o-amination of anilines showing excellent mono-substitution selectivity and high functional group tolerance has been developedWe thank the Spanish Government (MINECO, CTQ2012-35790) and the Madrid regional ...
Arrayás, Ramón Gómez +3 more
core +2 more sources
Inhibiting tryptophan metabolism enhances interferon therapy in kidney cancer. [PDF]
, 2016 Renal cell carcinoma (RCC) is increasing in incidence, and a complete cure remains elusive. While immune-checkpoint antibodies are promising, interferon-based immunotherapy has been disappointing.
Abu Aboud, Omran +13 more
core +2 more sources