Results 81 to 90 of about 14,953 (217)

Highly active and selective supported rhenium catalysts for aerobic oxidation of n-Hexane and n-Heptane [PDF]

open access: yes, 2018
A series of derivative C-scorpionate rhenium complexes, i.e., [ReCl2{NNC(O)C6H5} (Hpz)(PPh3)2] (A) (where Hpz is pyrazole), [ReCl2{NNC(O)C6H5}(Hpz)2(PPh3)] (B), [ReClF {NNC(O)C6H5}(Hpz)2(PPh3)] (C), and their precursor [ReOCl3(PPh3)2] (D), immobilized on
Alegria, Elisabete   +3 more
core   +2 more sources

Association Between the Dutch Mediterranean‐Dietary Approaches to Stop Hypertension Intervention for Neurodegenerative Delay (MIND‐NL) Diet Adherence and Systemic Tryptophan Metabolites in Older Adults at Risk of Cognitive Decline: An Exploratory Study

open access: yesMolecular Nutrition &Food Research, Volume 70, Issue 1, January 2026.
Following the MIND diet may support brain health in older adults at risk of cognitive decline by influencing tryptophan (TRP) metabolism. Plasma samples and dietary intake data from the HELI intervention trial were used. Bivariate latent change score modeling analysis showed that greater adherence to the MIND diet was linked to higher tryptophan levels,
Sonja Beers   +10 more
wiley   +1 more source

Comparative analysis of Bacillus weihenstephanensis KBAB4 spores obtained at different temperatures [PDF]

open access: yes, 2010
The impact of Bacillus weihenstephanensis KBAB4 sporulation temperature history was assessed on spore heat resistance, germination and outgrowth capacity at a temperature range from 7 to 30 °C. Sporulation rate and efficiency decreased at low temperature,
Abee, T., Garcia, D., Voort, M., van der
core   +2 more sources

Support Vector Machine Identification of Small Molecule Binders to an Understudied Allosteric Site of SARS‐CoV‐2 Mpro for Next‐Generation PROTAC‐Based Therapeutics

open access: yesArchiv der Pharmazie, Volume 358, Issue 12, December 2025.
An SVM‐based ML model identified 180 potential SARS‐CoV‐2 Mpro inhibitors. MST experiments confirmed three high‐affinity binders, with one showing Kd = 2.8 ± 0.9 μM. These compounds are non‐competitive, suggesting binding to a novel allosteric site.
Enrico Mario Alessandro Fassi   +7 more
wiley   +1 more source

Characterization of inhibitory effects of the potential therapeutic inhibitors, benzoic acid and pyridine derivatives, on the monophenolase and diphenolase activities of tyrosinase [PDF]

open access: yesIranian Journal of Basic Medical Sciences, 2015
Objective(s):Involvement of tyrosinase in the synthesis of melanin and cell signaling pathway has made it an attractive target in the search for therapeutic inhibitors for treatment of different skin hyperpigmentation disorders and melanoma cancers ...
Nematollah Gheibi   +4 more
doaj  

Plectranthus‐derived Abietanes as Protein Kinase C‐δ Activators: In Silico Design, Human Serum Albumin Interaction, and Stability Evaluation

open access: yesChemistry &Biodiversity, Volume 22, Issue 12, December 2025.
ABSTRACT Cancer remains a major global health challenge. Among protein kinases (PKCs), PKC‐δ acts as a tumor suppressor in colon cancer and represents a valuable therapeutic target. Human serum albumin (HSA) is gaining attention as an efficient drug carrier, while Plectranthus spp. offers a rich source of bioactive compounds.
Vera M. S. Isca   +4 more
wiley   +1 more source

Synthesis, characterisation and luminescent properties of lanthanide-organic polymers with picolinic and glutaric acids [PDF]

open access: yes
Three new lanthanide(III) complexes (Ln = Sm, Tb and Eu) of picolinic and glutaric acid were prepared and characterised. The crystal structure of the complex [Sm(glu)(pic)- (H2O)2] (where Hpic and H2glu stand for picolinic and glutaric acid ...
Amaral, Vítor S.   +8 more
core   +1 more source

Green and Sustainable Chemistry Approaches on Azide‐Based Click Reactions in Polymer Science

open access: yesMacromolecular Rapid Communications, Volume 46, Issue 23, December 5, 2025.
Click Chemistry, particularly the azide‐alkyne cycloaddition (AAC) reaction, has revolutionized polymer chemistry, enabling precise and efficient synthesis of advanced functional materials. With its high regioselectivity, mild reaction conditions, and versatility, AAC reactions align closely with the principles of Green and Sustainable Chemistry.
Hatice Mutlu   +3 more
wiley   +1 more source

Highly sensitive quantification of 7α-hydroxy-4-cholesten-3-one in human serum by LC-ESI-MS/MS

open access: yesJournal of Lipid Research, 2007
We describe a highly sensitive and specific method for the quantification of serum 7α-hydroxy-4-cholesten-3-one (C4), which has been used as a biomarker for bile acid biosynthesis.
Akira Honda   +6 more
doaj   +1 more source

Home - About - Disclaimer - Privacy