Results 61 to 70 of about 14,953 (217)

The mediating role of the kynurenine pathway in longitudinal associations between dietary intake and quality of life in colorectal cancer survivors up to 12 months posttreatment

International Journal of Cancer, Volume 159, Issue 1, Page 122-143, 1 July 2026.
What's New? Many colorectal cancer survivors experience reduced health‐related quality of life (HRQoL), often lasting years after diagnosis. Healthy dietary patterns and even individual macro‐ and micronutrients, however, can potentially improve HRQoL.
Daniëlle D. B. Holthuijsen, Judith J. M. Rijnhart, Eline H. van Roekel, Martijn J. L. Bours, Per M. Ueland, Stéphanie O. Breukink, Maryska L. G. Janssen‐Heijnen, Joop L. Konsten, Eric T. P. Keulen, Adrian McCann, Stefanie Brezina, Biljana Gigic, Jennifer Ose, Matty P. Weijenberg, Simone J. P. M. Eussen   +14 more
wiley   +1 more source

Comparison of the Plasma Metabolome Profiles Between the Internal Thoracic Artery and Ascending Aorta in Patients Undergoing Coronary Artery Bypass Graft Surgery Using Gas Chromatography Time-of-Flight Mass Spectrometry. [PDF]

, 2019
BackgroundThe left internal thoracic artery (LITA) has been used as the first conduit of choice in coronary artery bypass grafting (CABG) because of excellent long-term patency and outcomes.
Cho, Joo Youn, Hwang, Ho Young, Jang, Cholsoon, Jang, In Jin, Kim, Andrew HyoungJin, Kim, Ji Seong, Kim, Ki Bong   +6 more
core  

Preparation of (S)-tert-ButylPyOx and Palladium-Catalyzed Asymmetric Conjugate Addition of Arylboronic Acids [PDF]

, 2015
A. (S)-N-(1-Hydroxy-3,3-dimethylbutan-2-yl)picolinamide (2). A 1 L one-necked round-bottomed flask equipped with a 3.0 cm x 1.4 cm, egg-shaped, Teflon-coated magnetic stirring bar is sealed with a septum and connected via needle adapter to a two-tap ...
Holder, Jeffrey C., Shimizu, Hideki, Shockley, Samantha E., Stoltz, Brian M., Wiesenfeldt, Mario P.   +4 more
core   +1 more source

Chronic Low‐Dose Unsymmetrical Dimethylhydrazine Exposure in Rats: Multiorgan Mechanisms and Biomarker Identification

Journal of Applied Toxicology, Volume 46, Issue 6, Page 1987-2002, June 2026.
ABSTRACT Unsymmetrical dimethylhydrazine (UDMH), a highly toxic rocket propellant with known multiorgan effects, requires urgent characterization of its chronic low‐dose toxicity. Using an integrated approach including exploratory transcriptomics (n = 3/group) and metabolomic (n = 4/group) approaches in male Sprague–Dawley rats exposed to high‐dose ...
Fuzhou Liu, Bing Liu, Keli Wang, Xiaoyu Wang, Zhen Sun, Xiaojuan Pan, Zengming Zhao   +6 more
wiley   +1 more source

A Distinct Tryptophan Metabolic Phenotype Marks Severe Fatigue in Quiescent Crohn's Disease

JCC Plus, Volume 1, Issue 3, May 2026.
ABSTRACT Background Fatigue is a common and debilitating symptom in inflammatory bowel disease (IBD), but its underlying mechanisms remain unclear. Altered tryptophan metabolism may contribute to fatigue. Tryptophan is metabolized through the kynurenine, serotonin, and indole pathway, involving host and microbial processes. We aimed to explore the link
Paula I. Metselaar, Mees J. van der Hoff, Naomi V. Wieser, Olaf Welting, Antoine Lefèvre, Camille Dupuy, Patrick Emond, Joep P. M. Derikx, Wouter J. de Jonge, Geert R. A. M. D'Haens, Anje A. te Velde, Mark Löwenberg, Mohammed Ghiboub   +12 more
wiley   +1 more source

Similarity Between the Action of Pteridines and Tryptophan Metabolites on Lipid Metabolism

Pteridines, 1999
Incorporation of fatty acids into phospholipids has been investigated using samples of rat liver tissue homogenate, Krebs-Ringer-phosphate buffer (pH=7.4) containing 0.3% albumin, fatty acid mixture and glycerol. The addition of anthranilic acid (2.2 and
Rudzite Vera, Jurika Edite, Widner Bernhard, Fuchs Dietmar   +3 more
doaj   +1 more source

Modulation of Amide Bond Rotamers in 5-Acyl-6,7-dihydrothieno[3,2-c]pyridines [PDF]

, 2015
2-Substituted N-acyl-piperidine is a widespread and important structural motif, found in approximately 500 currently available structures, and present in nearly 30 pharmaceutically active compounds.
Lanyon-Hogg, T, Magee, AI, Masumoto, N, Ritzefeld, M, Rzepa, HS, Tate, EW   +5 more
core   +3 more sources

Enhancing Lipidomics With High‐Resolution Ion Mobility‐Mass Spectrometry

PROTEOMICS, Volume 26, Issue 4, Page 7-22, April 2026.
ABSTRACT Lipids, indispensable yet structurally intricate biomolecules, serve as critical regulators of cellular function and disease progression. Conventional lipidomics, constrained by limited resolution for isomeric and low‐abundance species, has been transformed by ion mobility‐mass spectrometry (IM‐MS).
Gaoyuan Lu, Shuling Xu, Penghsuan Huang, Lingjun Li   +3 more
wiley   +1 more source

Urinary N-methylnicotinamide and β-aminoisobutyric acid predict catch-up growth in undernourished Brazilian children [PDF]

, 2015
Enteric infections, enteropathy and undernutrition in early childhood are preventable risk factors for child deaths, impaired neurodevelopment, and later life metabolic diseases.
Guerrant, RL, Havt, A, Leite, Á, Lima, AAM, Lima, NL, Mayneris-Perxachs, J, Moore, SR, Moura, AF, Pinkerton, R, Soares, AM, Swann, JR   +10 more
core   +1 more source

Differential Analysis of IAA Anabolism Pathway Based on Bacillus cereus, Bacillus subtilis and Bacillus safensis Genome

Environmental Microbiology Reports, Volume 18, Issue 2, April 2026.
Three Bacillus species isolated from Platycladus orientalis rhizosphere in Taihang Mountains: Bacillus cereus has 3 IAA synthesis pathways (TAM, IAM, IPyA); Bacillus subtilis has IAM/IPyA; and Bacillus safensis only has IPyA (via whole‐genome sequencing).
Dongyue Hou, Xuejie Zhai, Kezhong Zhang, Jinteng Cui   +3 more
wiley   +1 more source