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Indoleamine 2,3-dioxygenase-regulated macrophages metabolic reprogramming rescues tacrolimus-induced nephrotoxicity. [PDF]
Ye M +10 more
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Anodic oxidation of paraquat herbicide on BDD electrode: comparative evaluation of variable effects and degradation mechanisms. [PDF]
Rabaaoui N +5 more
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Microbiome-metabolomics analysis insight into the effects of dietary chromium picolinate on abdominal fat deposition and lipid metabolism of ducks. [PDF]
Xie Y +10 more
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THE CRYSTAL STRUCTURE OF PICOLINIC ACID
Chemistry Letters, 1973Abstract The crystal structure of picolinic acid was determined by a three-dimensional X-ray analysis. The molecules are linked by two symmetric double minimum hydrogen bonds with a small potential barrier, N–H–N and O–H–O,and form a zig-zag chain.
Fusao Takusagawa, Akira Shimada
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Immunobiology of Picolinic Acid
1996Exposure of various cell types to IFN results in increased enzymatic activities leading to the breakdown of tryptophan and evidence exists to suggest that the catabolism of tryptophan may be connected to the biological effects of interferon (Carlin et al., 1989.
G, Melillo +3 more
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Picolinic Acid in Acrodermatitis Enteropathica
Journal of Pediatric Gastroenterology and Nutrition, 1984SummaryThree children with acrodermatitis enteropathica (AE) were treated with oral zinc dipicolinate (zinc‐PA). The daily dose of zinc required to prevent exacerbations, when administered as the dipicolinate complex, was one‐third the minimum amount of zinc required as the sulfate salt. The concentration of picolinic acid in the plasma of asymptomatic
I, Krieger, R, Cash, G W, Evans
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Microbial oxidation of kynurenic, xanthurenic and picolinic acids
Biochimica et Biophysica Acta, 1963Abstract 1. 1. Resulta of a study of the degradation of kynurenic acid by an Aerococcus are in agreement with a reaction sequence proposed for Pseudomonas by other workers. This sequence includes Compounds I and II below. 2. 2. Partial inhibition of oxidation of kynurenic acid by cell suspensions caused an accumulation of pyruvate with ...
S, DAGLEY, P A, JOHNSON
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Influence of picolinic acid on seizure susceptibility in mice
Pharmacological Reports, 2017The mechanism of drug resistance in epilepsy remains unknown. Picolinic acid (PIC) is an endogenous metabolite of the kynurenine pathway and a chelating agent added to dietary supplements. Both inhibitory and excitatory properties of PIC were reported.
Anna, Cioczek-Czuczwar +3 more
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Picolinic acid hydroxylase of Arthrobacter picolinophilus
Canadian Journal of Microbiology, 1974Picolinic acid is oxidized by cells and extracts of Arthrobacter picolinophilus to 6-hydroxypicolinic acid. The enzyme involved is a particulate hydroxylase which appears to incorporate the hydroxyl group of water into the substrate. The enzyme was purified about 60-fold.
R L, Tate, J C, Ensign
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