Results 151 to 160 of about 6,282 (195)
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New Derivatives of Picolinic Acid and Nicotinic Acid with Anticonvulsant Activity
Protein & Peptide Letters, 2005Previously obtained Pic-BZA is a potent anticonvulsant with low neurotoxicity, but its half-time of action is only about 15 min. In search for equally effective anticonvulsants but with a longer time of action fourteen Pic-BZA analogs were obtained.
Ryszard, Paruszewski +3 more
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Investigation of Picolinic Acid Extraction by Trioctylamine
International Journal of Chemical Reactor Engineering, 2011Picolinic acid is a pyridine compound with a carboxyl side chain at the 2-position. It is an isomer of nicotinic acid, which has the carboxyl side chain at the 3-position. Picolinic acid acts as a chelating agent of elements such as chromium, zinc, manganese, copper, iron, and molybdenum in the human body.
Tuyun, Amac Fatih, Uslu, Hasan
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Reductions of picolinic acid and dipicolinic acid at mercury cathodes
Journal of Electroanalytical Chemistry and Interfacial Electrochemistry, 1975Summary Picolinic acid and dipicolinic acid have been successfully reduced to the corresponding alcohols by controlled potential electrolysis at mercury cathodes in slightly acidic aqueous buffer solutions.
O.R. Brown, J.A. Harrison, K.S. Sastry
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Influence of picolinic acid on seizure susceptibility in mice
Pharmacological Reports, 2017The mechanism of drug resistance in epilepsy remains unknown. Picolinic acid (PIC) is an endogenous metabolite of the kynurenine pathway and a chelating agent added to dietary supplements. Both inhibitory and excitatory properties of PIC were reported.
Anna, Cioczek-Czuczwar +3 more
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6-Phosphoryl Picolinic Acids as Europium and Terbium Sensitizers
Inorganic Chemistry, 2011Three 6-phosphoryl picolinic acid (6PPA) derivatives were synthesized and used as europium and terbium sensitizers. Two of the three ligands (6-diethoxyphosphoryl picolinic acid (Hdeppa) and 6-monoethoxyphosphoryl picolinic acid (H(2)meppa)) are water-soluble, once complexed to lanthanide ions, while the third (6-dihydroxyphosphoryl picolinic acid (H(3)
Julien, Andres, Anne-Sophie, Chauvin
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Octadentate Picolinic Acid‐Based Bispidine Ligand for Radiometal Ions
Chemistry – A European Journal, 2017AbstractThe synthesis of the octadentate bispidine ligand bearing two picolinic acid pendant arms (H2bispa2), and its coordination chemistry with radionuclides relevant for nuclear medicine, namely indium(III) (111In), lutetium(III) (177Lu), and lanthanum(III) (as surrogate for 225Ac), are reported.
Peter Comba +7 more
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Journal of Organometallic Chemistry, 1991
Two types of complexes of diorganotin picolinates (i) R2Sn(Pic)2 [2:1] and (ii) [R2SnPic]2O [1:1] and of diorganotinpicolinate N-oxides (i) R2Sn(PicO)2 [2:1] and (ii) [R2SnPicO]2O [1:1] (R = CH3, n-C4H9, n-C8H17, C6H5CH2) have been prepared by reacting picolinic acid and picolinic acid N-oxide with diorganotin oxide in 2:1 and 1:1 ligand:metal molar ...
G.K. Sandhu, N.S. Boparoy
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Two types of complexes of diorganotin picolinates (i) R2Sn(Pic)2 [2:1] and (ii) [R2SnPic]2O [1:1] and of diorganotinpicolinate N-oxides (i) R2Sn(PicO)2 [2:1] and (ii) [R2SnPicO]2O [1:1] (R = CH3, n-C4H9, n-C8H17, C6H5CH2) have been prepared by reacting picolinic acid and picolinic acid N-oxide with diorganotin oxide in 2:1 and 1:1 ligand:metal molar ...
G.K. Sandhu, N.S. Boparoy
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Macrophage Activating Properties of The Tryptophan Catabolite Picolinic Acid
2003Recent studies have suggested a role for aminoacid catabolites as important regulators of macrophage (Mphi) activities. We reported previously that picolinic acid (PA), a tryptophan catabolite produced under inflammatory conditions and a costimulus with IFNgamma of Mphi effector functions, is a selective inducer of the Mphi inflammatory protein-1alpha (
Maria Carla, Bosco +5 more
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762. Silicon esters of picolinic acid
Journal of the Chemical Society (Resumed), 1961G. H. Searle, C. J. Wilkins
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