Results 121 to 130 of about 9,317 (205)

Therapy with murinized tobevibart and elebsiran is efficacious in a liver-chimeric mouse model of HDV infection

JHEP Reports
Background & Aims: Chronic hepatitis delta virus (HDV) infection represents the most severe form of viral hepatitis. HDV is a satellite virus of hepatitis B virus (HBV) and depends on the hepatitis B surface antigen (HBsAg) for envelopment and viral ...
Jiayi Zhou, Hannah Kaiser, Evelyn Rocha, Ashley N. Terrell, Davide Corti, Lisa A. Purcell, Florian A. Lempp, Andreas S. Puschnik   +7 more
doaj   +1 more source

Topically Applied Recombinant Chemokine Analogues Fully Protect Macaques from Vaginal Simian-Human Immunodeficiency Virus Challenge [PDF]

, 2017
Effective strategies for preventing human immunodeficiency virus infection are urgently needed, but recent failures in key clinical trials of vaccines and microbicides highlight the need for new approaches validated in relevant animal models.
Green, Linda C., Hartley, Oliver, Lederman, Michael M., Lifson, Jeffrey D., Ling, Binhua, Mosier, Donald, Offord, Robin, Piatak, Michael, Ribka, Erin P., Veazey, Ronald S.   +9 more
core  

Approaches to hepatitis C treatment and cure using NS5A inhibitors

Infection and Drug Resistance, 2014
James J Kohler,1,2 James H Nettles,1,2 Franck Amblard,1,2 Selwyn J Hurwitz,1,2 Leda Bassit,1,2 Richard A Stanton,1 Maryam Ehteshami,1 Raymond F Schinazi1,2 1Center for AIDS Research and Department of Pediatrics, Emory University School of Medicine ...
Kohler JJ, Nettles JH, Amblard F, Hurwitz SJ, Bassit L, Stanton RA, Ehteshami M, Schinazi RF   +7 more
doaj  

CELMoD-antibody conjugates unlock a CD38 feedback loop in multiple myeloma. [PDF]

Acta Pharm Sin B
Jin J.
europepmc   +1 more source

Reply to Peigneur et al. The Helix Ring Peptide U11 from the Venom of the Ant, <i>Tetramorium bicarinatum</i>, Acts as a Putative Pore-Forming Toxin, Not a New Kv1.3 Channel Blocker. Comment on "Boy et al. A New Kv1.3 Channel Blocker from the Venom of the Ant <i>Tetramorium bicarinatum</i>. <i>Toxins</i> 2025, <i>17</i>, 379". [PDF]

Toxins (Basel)
Boy G, Jouvensal L, Téné N, Carayon JL, Bonnafé E, Paquet F, Treilhou M, Loth K, Billet A.   +8 more
europepmc   +1 more source

Structure-Guided Design of Peptide Inhibitors Targeting Class I Viral Fusion Proteins. [PDF]

Pathogens
Gonepudi NK, Baffour Awuah H, Xu W, Katte RH, Lu M.   +4 more
europepmc   +1 more source

Combinatorial Chemistry Online Volume 15, Issue 5, May 2013 [PDF]

, 1963
Terrett, N.K.
core   +8 more sources

A β-lactamase inhibitory protein mutant displays high potency and a broad inhibition profile due to an altered binding mode with β-lactamases. [PDF]

J Biol Chem
Rivera P, Lu S, Ngango D, Sankaran B, Venkataram Prasad B, Palzkill T.   +5 more
europepmc   +1 more source

Computational refinement and multivalent engineering of complementarity-determining region-grafted nanobodies on a humanized scaffold for retaining antiviral efficacy. [PDF]

Brief Bioinform
Huo L, Qin Q, Tian T, Zhang X, He X, Cao Y, Zhang T, Xu Y, Huang Q.   +8 more
europepmc   +1 more source

Margatoxin is a non-selective inhibitor of human Kv1.3 K+ channels [PDF]

, 2019
Bartók, Ádám, Hajdu, Péter, Panyi, György, Somodi, Sándor, Szántó, Gábor Tibor, Tóth, Ágnes, Varga, Zoltán   +6 more
core   +1 more source