Results 151 to 160 of about 9,317 (205)

Electrophysiological characterization of the state-dependent inhibition of Kv7.1 and I_Ks by UCL2077. [PDF]

Mol Pharmacol
Sastre D, Kyriakis E, Schauer J, Chan M, Dou Y, Eldstrom J, Fedida D.   +6 more
europepmc   +1 more source

Deferasirox Derivatives as Inhibitors of Kallikrein-Related Peptidases Associated to Neurodegenerative Diseases. [PDF]

ChemMedChem
Boumali R, David E, Chaaya N, Lucas M, Aït Amiri S, Lefort V, Nina-Diogo A, Salmain M, Petropoulos I, Corcé V, El Amri C, Botuha C.   +11 more
europepmc   +1 more source

Expanding the repertoire of Antibody Drug Conjugate (ADC) targets with improved tumor selectivity and range of potent payloads through in-silico analysis. [PDF]

PLoS One
Kathad U, Biyani N, Peru Y Colón De Portugal RL, Zhou J, Kochat H, Bhatia K.   +5 more
europepmc   +1 more source

KT-253, a Novel MDM2 Degrader and p53 Stabilizer, Has Superior Potency and Efficacy than MDM2 Small-Molecule Inhibitors. [PDF]

Mol Cancer Ther
Chutake YK, Mayo MF, Dumont N, Filiatrault J, Breitkopf SB, Cho P, Chen D, Dixit VS, Proctor WR, Kuhn EW, Bollinger Martinez S, McDonald AA, Qi J, Hu KN, Karnik R, Growney JD, Sharma K, Schalm SS, Gollerkeri AM, Mainolfi N, Williams JA, Weiss MM.   +21 more
europepmc   +1 more source

Cvill6 and Cvill7: Potent and Selective Peptide Blockers of Kv1.2 Ion Channel Isolated from Mexican Scorpion <i>Centruroides villegasi</i>. [PDF]

Toxins (Basel)
Shakeel K, Naseem MU, Olamendi-Portugal T, Zamudio FZ, Possani LD, Panyi G.   +5 more
europepmc   +1 more source

Preclinical virology profiles of the HIV-1 capsid inhibitors VH4004280 and VH4011499. [PDF]

Antimicrob Agents Chemother
Wang C, Huang H, Valera L, Parcella K, Iwuagwu C, McAuliffe B, Falk PJ, O'Boyle Ii DR, Rose RE, Padilla RR, Wu C, Xiong Y, Kadow J, Hanumegowda U, Sardo L, Gillis EP, Krystal M, Fridell RA.   +17 more
europepmc   +1 more source

A human monoclonal antibody based immunoenzymetric assay to measure Fel d 1 concentrations in cat hair and pelt allergenic extracts. [PDF]

Front Allergy
Rabin RL, Croote D, Chen A, Dobrovolskaia E, Wong JJW, Grossman J, Hamilton RG.   +6 more
europepmc   +1 more source

Drugging Challenging Cancer Targets Using Fragment-Based Methods. [PDF]

Chem Rev
Fesik SW.
europepmc   +1 more source

Hepatocellular Carcinoma and Antibody Drug Conjugates: A Systematic Review. [PDF]

Cureus
Maddukuri S, Haddad RR, Battula NS, Chay T, Patel T, Dumaru N, Mohammed L.   +6 more
europepmc   +1 more source

How a Medicinal Chemistry Project Changed the Way Prostate Cancer is Diagnosed and Treated. [PDF]

J Med Chem
Kozikowski AP, Neale J.
europepmc   +1 more source