Results 161 to 170 of about 9,317 (205)

Enhanced Plasma Stability and Potency of Aryl/Acyloxy Prodrugs of a BTN3A1 Ligand. [PDF]

ACS Med Chem Lett
Singh U, Pawge G, Rani S, Hsiao CC, Wiemer DF, Wiemer AJ.   +5 more
europepmc   +1 more source

Discovery of a PDE4B and PDE4D selective bifunctional degrader for management of chronic inflammatory disorders. [PDF]

J Transl Autoimmun
Shakya A, Liu Q, Lai C, Baker S, Greene S, Erdman P, Rathnayake A, Schoolmeesters A, Blair CM, Kyurkchieva E, Rajapakse N, Lam I, Sin YY, Baillie GS, Huang S, Chourasia AH, Fung L.   +16 more
europepmc   +1 more source

Aptamer-Based Delivery of Genes and Drugs Across the Blood-Brain Barrier. [PDF]

Pharmaceuticals (Basel)
Yang L, Yin Y, Liu X, Guo B.
europepmc   +1 more source

Peptide-induced infant status epilepticus causes neuronal death and synaptic reorganization [PDF]

, 1995
BARAM, TZ
core  

An Amazing 30-Year Journey around the DABO Family: A Medicinal Chemistry Lesson on a Versatile Class of Non-nucleoside HIV-1 Reverse Transcriptase Inhibitors. [PDF]

J Med Chem
Fabbrizi E, Chernyshov VV, Fiorentino F, Sbardella G, Ragno R, Nawrozkij M, Ivanov R, Rotili D, Mai A.   +8 more
europepmc   +1 more source

Drug Discovery Strategies for Kallikrein-Related Peptidases. [PDF]

Int J Mol Sci
Dreyer T, Schuster D, Magdolen V, Goettig P.   +3 more
europepmc   +1 more source

The Current Landscape of Modular CAR T Cells. [PDF]

Int J Mol Sci
Joechner AH, Mach M, Li Z.
europepmc   +1 more source

Recent progress in therapeutic applications of fluorinated five-membered heterocycles and their benzo-fused systems. [PDF]

RSC Adv
Abbas AA, Farghaly TA, Dawood KM.
europepmc   +1 more source

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Discovery of a Non-competitive TNFR1 Antagonist Affibody with Picomolar Monovalent Potency That Does Not Affect TNFR2 Function

Molecular Pharmaceutics, 2023
Tumor necrosis factor (TNF) is a key regulator of immune responses and plays a significant role in the initiation and maintenance of inflammation. Upregulation of TNF expression leads to several inflammatory diseases, such as Crohn's, ulcerative colitis, and rheumatoid arthritis.
Nagamani Vunnam, MaryJane Been, Evan Huber, Carolyn Paulson, Sophia Szymonski, Benjamin J. Hackel, Jonathan N. Sachs   +6 more
openaire   +2 more sources