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Viral metagenomic analysis of fecal samples from <i>Bos grunniens</i> on the Qinghai-Tibet Plateau reveals novel picornaviruses and diverse CRESS-DNA viruses. [PDF]
Chen J +8 more
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Treatment of picornavirus infections
Antiviral Research, 2002The picornaviruses are a diverse group of viral pathogens that together comprise the most common causes of infections of humans in the developed world. Within the picornavirus family are three well-known groups of human pathogens-the enteroviruses (including polioviruses, coxsackieviruses, and echoviruses), the rhinoviruses, and the hepatoviruses ...
Harley A Rotbart
exaly +3 more sources
Intracellular determinants of picornavirus replication
Trends in Microbiology, 1999Viruses replicate in a restricted number of hosts and tissues. In addition to viral receptors, several intracellular factors can be involved in determining tissue tropism. Many proteins have recently been implicated in picornavirus translation and RNA replication.
Raúl Andino +2 more
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PICORNAVIRUS EPIDEMIC CONJUNCTIVITIS IN SINGAPORE
Lancet, The, 1972Abstract Outbreaks of picornavirus epidemic conjunctivitis in 1970 and 1971 in Singapore have been studied. The 1971 outbreak was caused by a virus identical or closely related to the acute haemorrhagic conjunctivitis (A.H.C.) virus isolated in Japan in 1971, and not by reappearance of the Singapore epidemic conjunctivitis (S.E.C.) virus (1970). The S.
M Yin-Murphy
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Divergent picornavirus IRES elements
Virus Research, 2009Internal ribosome entry site (IRES) elements were first identified about 20 years ago within the 5' untranslated region of picornavirus RNAs. They direct a cap-independent mechanism of translation initiation on the viral RNA. Within the picornavirus family it is now known that there are four classes of IRES element which vary in size (450-270 nt), they
Graham Belsham
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Selective inhibitors of picornavirus replication
Medicinal Research Reviews, 2008AbstractPicornaviruses cover a large family of pathogens that have a major impact on human but also on veterinary health. Although most infections in man subside mildly or asymptomatically, picornaviruses can also be responsible for severe, potentially life‐threatening disease.
Johan Neyts
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2013
The essential event in picornavirus entry is the delivery of the RNA genome to the cytoplasm of a target cell, where replication occurs. In the past several years progress has been made in understanding the structural changes in the virion important for uncoating and RNA release. In addition, for several viruses the endocytic mechanisms responsible for
Jeffrey M, Bergelson, Carolyn B, Coyne
openaire +2 more sources
The essential event in picornavirus entry is the delivery of the RNA genome to the cytoplasm of a target cell, where replication occurs. In the past several years progress has been made in understanding the structural changes in the virion important for uncoating and RNA release. In addition, for several viruses the endocytic mechanisms responsible for
Jeffrey M, Bergelson, Carolyn B, Coyne
openaire +2 more sources

