Results 131 to 140 of about 24,514 (173)

Treatment of picornavirus infections

Antiviral Research, 2002
The picornaviruses are a diverse group of viral pathogens that together comprise the most common causes of infections of humans in the developed world. Within the picornavirus family are three well-known groups of human pathogens-the enteroviruses (including polioviruses, coxsackieviruses, and echoviruses), the rhinoviruses, and the hepatoviruses ...
Harley A Rotbart
exaly   +3 more sources

Intracellular determinants of picornavirus replication

Trends in Microbiology, 1999
Viruses replicate in a restricted number of hosts and tissues. In addition to viral receptors, several intracellular factors can be involved in determining tissue tropism. Many proteins have recently been implicated in picornavirus translation and RNA replication.
Raúl Andino   +2 more
exaly   +3 more sources

PICORNAVIRUS EPIDEMIC CONJUNCTIVITIS IN SINGAPORE

Lancet, The, 1972
Abstract Outbreaks of picornavirus epidemic conjunctivitis in 1970 and 1971 in Singapore have been studied. The 1971 outbreak was caused by a virus identical or closely related to the acute haemorrhagic conjunctivitis (A.H.C.) virus isolated in Japan in 1971, and not by reappearance of the Singapore epidemic conjunctivitis (S.E.C.) virus (1970). The S.
M Yin-Murphy
exaly   +3 more sources

Divergent picornavirus IRES elements

Virus Research, 2009
Internal ribosome entry site (IRES) elements were first identified about 20 years ago within the 5' untranslated region of picornavirus RNAs. They direct a cap-independent mechanism of translation initiation on the viral RNA. Within the picornavirus family it is now known that there are four classes of IRES element which vary in size (450-270 nt), they
Graham Belsham
exaly   +4 more sources

Selective inhibitors of picornavirus replication

Medicinal Research Reviews, 2008
AbstractPicornaviruses cover a large family of pathogens that have a major impact on human but also on veterinary health. Although most infections in man subside mildly or asymptomatically, picornaviruses can also be responsible for severe, potentially life‐threatening disease.
Johan Neyts
exaly   +3 more sources

Picornavirus Entry

2013
The essential event in picornavirus entry is the delivery of the RNA genome to the cytoplasm of a target cell, where replication occurs. In the past several years progress has been made in understanding the structural changes in the virion important for uncoating and RNA release. In addition, for several viruses the endocytic mechanisms responsible for
Jeffrey M, Bergelson, Carolyn B, Coyne
openaire   +2 more sources

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