Results 101 to 110 of about 21,155 (219)

Increased expression of collagens, transforming growth factor-β1, and -β3 in gluteal muscle contracture [PDF]

open access: yes, 2010
Backgroud Gluteal muscle contracture (GMC) is a multi-factor human chronic fibrotic disease of the gluteal muscle. Fibrotic tissue is characterized by excessive accumulation of collagen in the muscle's extracellular matrix.
Chen-Guang Zhao   +4 more
core   +2 more sources

Cytochrome P450 1A1 influences obesity‐induced pulmonary hypertension

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose The contribution of obesity to pulmonary arterial hypertension (PAH) pathophysiology remains poorly understood. Adipose tissue synthesises estrogens via cytochrome P450 (CYP) 19A1 (aromatase), whereas circulating estrogens are metabolised in the lung by CYP1A1.
Joshua P. Dignam   +12 more
wiley   +1 more source

405 nm light exposure of osteoblasts and inactivation of bacterial isolates from arthroplasty patients : potential for new disinfection applications? [PDF]

open access: yes, 2013
Infection rates after arthroplasty surgery are between 1-4 %, rising significantly after revision procedures. To reduce the associated costs of treating these infections, and the patients' post-operative discomfort and trauma, a new preventative method ...
Anderson, John   +7 more
core   +2 more sources

Pharmacological inhibition of hydroxysteroid 11‐beta dehydrogenase type 1 (11‐βHSD1) after myocardial infarction preserves cardiac function in a translational mini‐pig model

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Plasma glucocorticoids increase acutely after MI, thereafter tissue levels are amplified selectively within cells expressing 11‐ßhydroxysteroid dehydrogenase type 1 (11‐ßHSD1) that regenerates active glucocorticoids from circulating metabolites.
Sara Al Disi   +19 more
wiley   +1 more source

Evaluation of biological behavior of odontogenic keratocyst and orthokeratinized odontogenic cyst using picrosirius red stain: A clinicopathological retrospective study

open access: yesJournal of Dr. NTR University of Health Sciences, 2019
Background: Odontogenic keratocyst (OKC) and orthokeratinized odontogenic cyst (OOC) show considerable difference in biological behavior, and the study of the organization of collagen fibers may be helpful in understanding the nature of these variants ...
Suvarna Manthapuri   +5 more
doaj   +1 more source

Immunohistological Evaluation of Peri‐Implant Soft Tissue Grafting Using a Porcine Dermal Matrix—A Human Histological Study

open access: yesClinical Oral Implants Research, EarlyView.
ABSTRACT Introduction The aim was the immunohistological evaluation of a porcine dermal matrix (PDM) in comparison to a non‐augmented control group for peri‐implant tissue thickening. Materials and Methods This human histological study involved the placement of PDM in the test group (20 patients) during implant placement, while the control group ...
F. R. S. Michallek   +9 more
wiley   +1 more source

Enhanced Osteogenesis of Adipose-Derived Stem Cells by Regulating Bone Morphogenetic Protein Signaling Antagonists and Agonists. [PDF]

open access: yes, 2016
UnlabelledAlthough adipose-derived stem cells (ASCs) are an attractive cell source for bone tissue engineering, direct use of ASCs alone has had limited success in the treatment of large bone defects.
Aghaloo, Tara L   +11 more
core   +2 more sources

Comparative analysis of metabolic and functional cardiac alterations in diet‐ and genetically induced mouse models of cardiac dysfunction

open access: yesThe FEBS Journal, EarlyView.
Dietary and genetic stress trigger different routes to heart failure. In mice, a carbohydrate‐free high‐fat diet caused mitochondrial dysfunction and impaired energy production with preserved pumping function, while genetic obesity led to heart enlargement, fibrosis, and reduced function.
Christiane Ott   +9 more
wiley   +1 more source

The Application of Optical Coherence Tomography in Musculoskeletal Disease [PDF]

open access: yes, 2013
Many musculoskeletal disorders (MDs) are associated with irreversible bone and cartilage damage; this is particularly true for osteoarthritis (OA).
Brezinski, Mark Edward   +4 more
core   +2 more sources

Integrative Computational and Experimental Approaches Reveal the Protective Role of Moderate Caffeine Intake Against Apical Periodontitis Induced Bone Loss

open access: yesInternational Endodontic Journal, EarlyView.
ABSTRACT Aim To investigate whether moderate systemic caffeine intake modulates the progression of apical periodontitis (AP) and associated alveolar bone loss, combining in vivo rat experiments with in silico molecular docking to explore potential mechanisms. Methodology Male Wistar rats were randomly assigned to four groups (n = 8 per group): control,
Matheus Ferreira Lima Rodrigues   +12 more
wiley   +1 more source

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