Results 81 to 90 of about 13,582 (200)

Impact of recurrent dehydration with mild periodic water restriction on blood pressure and renal function in male spontaneously hypertensive rats

open access: yesExperimental Physiology, EarlyView.
Abstract The kidneys regulate fluid balance but are susceptible to adverse effects of inadequate hydration. Epidemiological studies have linked low water intake to renal dysfunction and chronic kidney disease. Previously we showed that restricting water intake to a single 2‐h period daily for 4 weeks promotes hypertension as well as renal inflammation,
Katrina M. Mirabito Colafella   +7 more
wiley   +1 more source

Regeneration of the lizard heart after cryoinjury

open access: yesExperimental Physiology, EarlyView.
Abstract Lizards are renowned for their tremendous potential to heal tissues and organs after injury, but little is known about myocardial regeneration in reptiles generally. Here, we study cardiac regeneration in the leopard gecko (Eublepharis macularius) to fill the knowledge gap between traditional models of poikilothermic (zebrafish) and ...
Martina Gregorovicova   +5 more
wiley   +1 more source

Tumor Associated Macrophages in Relation to Collagen Quality and Their Role in Aggressiveness of Giant Cell Granulomas of the Jaws [PDF]

open access: yesThe Egyptian Journal of Histology
Background: An ambiguity persists regarding variation in clinical aggressiveness of different oral lesions, among which are the giant cell granulomas.
Nermeen Afifi   +3 more
doaj   +1 more source

Semaglutide impacts skeletal muscle to a similar extent as caloric restriction in mice with diet‐induced obesity

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Four weeks of semaglutide treatment causes significant reductions in total body weight, fat mass, lean mass, and grip strength in mice with diet induced obesity. Mice treated with semaglutide lost a greater amount of total body weight and fat mass compared to mice fed fed a calorie matched diet.
S. Jeromson   +12 more
wiley   +1 more source

Caloric restriction and aerobic exercise differentially counteract muscle–tendon dysfunction following diet‐induced obesity in C57BL/6J mice

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Diet‐induced obesity induced fibro‐adipogenic remodelling of the muscle–tendon unit, characterized by increased fibrosis, reduced specific force, impaired relaxation kinetics, elevated hysteresis, and reduced aerobic capacity and glucose tolerance.
Leonardo Cesanelli   +9 more
wiley   +1 more source

Effect of Tokishakuyakusan on Anemia in a Rat Model of Salt‐Sensitive Hypertension

open access: yesTraditional &Kampo Medicine, Volume 13, Issue 2, August 2026.
ABSTRACT Aim Anemia is prevalent in patients with cardiac and renal diseases and is associated with morbidity and mortality. Consequently, new strategies for managing anemia are expected in these patients. Tokishakuyakusan, a Kampo medicine, is clinically used to treat various conditions, such as anemia and chronic nephritis.
Yoshiro Naito   +3 more
wiley   +1 more source

Tipos de colágeno na fibrose hepática esquistossomótica de Symmers

open access: yesRevista da Sociedade Brasileira de Medicina Tropical, 1983
Os AA. estudaram o tipo de colágeno em cortes histológicos de fragmentos de fígado de 12 indivíduos portadores da forma hepatesplênica da esquistossomose mansoni, pela técnica de coloração pelo Sirius Supra Red F3BA.
Pedro Raso   +3 more
doaj  

Picrosirius red staining for histology v1

open access: yes
Picrosirius red (PSR, aka Sirius red) staining is a histochemical technique for the identification of collagen and its specificity makes it suitable for robust quantitative assessments of collagen in tissue sections. Such digital image analysis is particularly valuable for the evaluation of fibrosis and tissue remodelling.
openaire   +1 more source

Picrosirius Red (PSR) Staining and Quantification in Mouse Ovaries v1

open access: yes
Picrosirius Red (PSR) staining is used to visualize collagen fibers in various tissues. When PSR binds to collagen fibers (specifically collagen I and III), it results in a dark red stain whereas the cytoplasmic regions appear yellow or faintly pink [1, 2].Generally, ovarian non-fibrotic regions stain darker pink than liver non-fibrotic regions ...
Francesca E. Duncan, Michele T Pritchard
openaire   +1 more source

Dual Action of Dipyridamole in Experimental Rheumatoid Arthritis: Suppression of Joint Inflammation and Upregulation of Muscle Anabolism via Adenosine and AMPK Pathways

open access: yesArthritis &Rheumatology, Volume 78, Issue 7, Page 1535-1553, July 2026.
Objective Rheumatoid sarcopenia, characterized by the progressive loss of skeletal muscle mass and function, is a frequent comorbidity in rheumatoid arthritis (RA), linked to prolonged, severe systemic inflammation. Purinergic signaling (adenosine, AMP, and ATP) plays a crucial role in inflammation, myogenesis, and muscle hypertrophy.
Miguel Marco‐Bonilla   +13 more
wiley   +1 more source

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