Results 61 to 70 of about 13,582 (200)

An experimental model for the study of collagen fibers in skeletal muscle Modelo experimental para o estudo de fibras de colágeno no músculo esquelético

Acta Cirúrgica Brasileira, 2012
PURPOSE: To examine histological and histomorphometric techniques for measuring collagen in skeletal muscle. METHODS: The following staining methods were used in the study: hematoxylin and eosin, Masson's trichrome, reticulin, and picrosirius red, and ...
Eliziane Nitz de Carvalho Calvi, Fábio Xerfan Nahas, Marcus Vinícius Barbosa, José Augusto Calil, Silvia Saiuli Miki Ihara, Marcelo de Souza Silva, Marcello Fabiano de Franco, Lydia Masako Ferreira   +7 more
doaj   +1 more source

Maternal Lead Exposure Induces Glandular Alterations in the Salivary Glands of Rat Male Offspring

Environmental Toxicology, EarlyView.
ABSTRACT Lead (Pb) is a widely distributed environmental pollutant that is highly noxious due to its toxicokinetic characteristics. Pb exposure can damage vital organ systems, including the central nervous and stomatognathic systems. As salivary glands play an important role in oral homeostasis, this study aimed to investigate the effects of maternal ...
Rayssa Maitê Farias Nazário, Deiweson Souza‐Monteiro, Walessa Alana Bragança Aragão, Luciana Eiró‐Quirino, Leonardo Oliveira Bittencourt, Raquel Fernanda Gerlach, Antônio Hernandes Chaves‐Neto, Michael Aschner, Rafael Rodrigues Lima   +8 more
wiley   +1 more source

Neurokinin‐1 receptor activation protects against cardiac fibrosis, inflammation and diastolic dysfunction in type 2 diabetic mice

British Journal of Pharmacology, EarlyView.
Background and Purpose The pathogenesis of type 2 diabetes mellitus (T2DM)‐induced cardiomyopathy involves cardiac fibrosis that leads to diastolic dysfunction. We established that replacement of lost substance P (SP) that occurs in T2DM reduces cardiac fibrosis and decreases inflammation in T2DM mice and non‐human primates.
Alexander Widiapradja, Heather Connery, Brody J. Helmick, Kallie J. Schafner, Vamsi Manchikalapudi, Hannah Horvath, Sophia Gugino, Tamas Kriska, Anja Herrnreiter, Evan DeVallance, William B. Campbell, Scott P. Levick   +11 more
wiley   +1 more source

PICROSIRIUS RED AND MASSON'S TRICHROME STAINING TECHNIQUES AS TOOLS FOR DETECTION OF COLLAGEN FIBERS IN THE SKIN OF DOGS WITH ENDOCRINE DERMATOPATHOLOGIES

Ciência Animal Brasileira, 2019
Canine endocrinopathies, such as hypothyroidism and hyperadrenocortism,induce typical dermatological alterations. Collagen fibers are significant for the maintenance of structural integrity,as well as in the determination of tissue function.
Glícia Meneses Costa, Steffi Lima Araujo, Francisco Antônio Félix Xavier Júnior, Glayciane Bezerra de Morais, João Alison de Moraes Silveira, Daniel de Araújo Viana, Janaina Serra Azul Monteiro Evangelista   +6 more
doaj  

In Vivo Photoacoustic Ultrasound (PAUS) Assay for Monitoring Tendon Collagen Compositional Changes during Injury and Healing

Diagnostics
Tendon injury and healing involve significant changes to tissue biology and composition. Current techniques often require animal sacrifice or tissue destruction, limiting assessment of dynamic changes in tendons, including treatment response, disease ...
Joseph B. Newton, Courtney A. Nuss, Stephanie N. Weiss, Rebecca L. Betts, Chandra M. Sehgal, Louis J. Soslowsky   +5 more
doaj   +1 more source

Pharmacological activation of NO‐cGMP signalling attenuates metabolic dysfunction‐associated steatohepatitis

British Journal of Pharmacology, EarlyView.
Background and Purpose Metabolic dysfunction‐associated steatohepatitis (MASH) is linked to activation of hepatic stellate cells (HSCs) to α‐smooth muscle actin–positive myofibroblasts that produce collagen and proinflammatory cytokines. Quiescent HSCs express the NO‐cGMP signalling axis.
Krithika Rajeeth, Malte Roessing, Moritz Lehners, Lisa Dietz, Anja Schmitt, Stephan Hailfinger, Andreas Peter, Leticia Quintanilla‐Martinez, Irene Gonzalez‐Menendez, Ingmar Mederacke, German Ott, Peter Sandner, Matthias Schwab, Robert Feil, Susanne Feil   +14 more
wiley   +1 more source

Colagenoma eruptivo em paciente HIV+ Eruptive collagenoma in an HIV-positive patient

Anais Brasileiros de Dermatologia, 2008
Colagenomas são hamartomas do tecido conjuntivo gerados por aumento anormal do colágeno dérmico. O colagenoma eruptivo caracteriza-se por pequenos nódulos duros, assintomáticos, sem relato de trauma ou processo inflamatório prévios.
Daniel Dal'Asta Coimbra, Joana Cabral Lustosa, Denise de Freitas Sarmento, Ricardo Barbosa Lima, Osvania M. N. Pessoa   +4 more
doaj   +1 more source

Chd4 and ThPOK cooperate to preserve structural and electrophysiological integrity of the adult heart through Sprr1a repression

The FEBS Journal, EarlyView.
Chd4/NuRD and ThPOK cooperate to maintain transcriptional repression and nuclear organization in adult cardiomyocytes. Chd4 loss reduces miR‐150‐5p, relieving repression of Sprr1a, while ThPOK loss further enhances Sprr1a activation, possibly through altered chromatin–lamina interactions.
Fadoua El Abdellaoui‐Soussi, Apolonia Novillo, Rocío Brea, Marta Ysbert, Lorena Cussó, Gonzalo Pizarro‐Sánchez, Manuel Desco, Iván Hernández, Ángel Luis Armesilla, Ignacio Pérez de Castro, Alicia R. Folgueras, Juan Miguel Redondo, Pablo Gómez‐del Arco   +12 more
wiley   +1 more source

Advancing collagen‐related pathology assessment through second‐harmonic generation imaging

Journal of Microscopy, EarlyView.
Abstract Collagen remodelling and dysregulation are the hallmarks of diverse pathological conditions. In this context, second‐harmonic generation (SHG) imaging has emerged as a powerful label‐free modality for assessing collagen. This offers submicron resolution, intrinsic optical sectioning, and deeper imaging capabilities without the need for ...
Jackson Rodrigues, Manikanth Karnati, Gagan Raju, Edwin Pious, Ankur Gogoi, Guan‐Yu Zhuo, Nirmal Mazumder, Fu‐Jen Kao   +7 more
wiley   +1 more source

Dual Beneficial Effects of Topical l‐Glutamine on Oral Mucositis in 5‐Fluorouracil‐Treated Mice

Journal of Oral Pathology &Medicine, EarlyView.
ABSTRACT Background Oral mucositis is a severe health and economic problem that occurs in about 40%–90% of patients undergoing cancer treatments. Systemic or topical application of l‐glutamine has been shown to improve mucosal healing and ameliorate oral mucositis (OM) symptoms according to clinical score systems.
Juliana Francisca Grossi Heleno, Igor de Campos Fontes, Leticia Cristine Cardoso dos Santos, Victor Prokop Gonçalves Campos, Iury Berckmann Freitas Gomes, Derek William Gilroy, Silvia Passos Andrade, Paula Peixoto Campos   +7 more
wiley   +1 more source