Results 111 to 120 of about 16,762 (196)

Collagen remodeling in equine exuberant granulation tissue characterized by Picrosirius Red staining

, 2023
Exuberant granulation tissue (EGT) is a disorder of second intention wound healing at distal limbs of horses. EGT is characterized by hyperproliferating granulation tissue.
De Spiegelaere, Ward, Michler, Jule Kristin, Partusch, Lena   +2 more
core  

Evaluation of Collagen Fibers in Oral Leukoplakia, Oral Submucous Fibrosis and Oral Squamous Cell Carcinoma using Picrosirius Red by Polarizing Microscopy [PDF]

, 2020
BACKGROUND: In India oral squamous cell carcinoma is a common malignancy accounting for 50-70% of total cancer mortality. Oral squamous cell carcinoma arise either de novo or from oral potentially malignant disorders mainly leukoplakia.
Kalpana, K
core  

Nanomaterial Strategies for Pulmonary Delivery of Immunotherapeutics in Lung Cancer Treatment

Advanced Healthcare Materials, Volume 15, Issue 34, 11 September 2026.
Inhalable immunotherapeutic nanomedicines enable organ‐selective immune modulation by overcoming pulmonary delivery barriers and concentrating therapy within lung tumors. This Review defines how nanomaterial properties govern airway deposition, retention, cellular partitioning, and immune activation across vaccines, checkpoint blockade, STING agonists,
Han Zhang, Wei Tang
wiley   +1 more source

Association of patient age with Picrosirius red collagen content in prostate tissues.

, 2014
The association of Picrosirius red collagen content and patient age at time of surgery was investigated in cohorts of BPH only tissues (TURP set), a combination of BPH and normal prostate tissue (TMA set [all patients]), and a subset of only normal ...
Tyler M. Bauman (638401), Wei Huang (36889), Chad M. Vezina (383839), William A. Ricke (279015), Tristan M. Nicholson (638402), Kevin W. Eliceiri (140016), Lisa L. Abler (638403)   +6 more
core   +1 more source

Fibrotic remodeling in the NOD/ShiLtJ mouse model of Sjögren’s disease: insights from single-cell transcriptomics and AI-driven ECM quantification

Frontiers in Immunology
IntroductionSjögren's Disease (SjD) is an autoimmune disorder characterized by salivary gland hypofunction and lymphocytic infiltration, yet the contribution of fibrosis to glandular dysfunction remains unclear.MethodsWe evaluated the NOD/ShiLtJ mouse as
Jennifer M. Morrissey, Jennifer M. Morrissey, Deirdre A. Nelson, Li Chen, Mathieu Petitjean, Joey R. Tavarez, Joey R. Tavarez, Amber L. Altrieth-Flagg, Amber L. Altrieth-Flagg, Nicholas L. Moskwa, Renae Williams-Atkinson, Ben Fowler, Rafael Pena, Rafael Pena, Kennedi Weston, Kennedi Weston, Nikhita Kumar, Nikhita Kumar, Nathan Aist, Melinda Larsen, Melinda Larsen   +20 more
doaj   +1 more source

MASH Background Confers Enhanced Disease Susceptibility and Acetaminophen Toxicity in iPSC‐Derived Liver Organoids

Advanced Science, Volume 13, Issue 53, 24 September 2026.
This work establishes a novel method for generating multicellular liver organoids from control and MASH donor iPSCs. The model recapitulates several disease‐specific characteristics, with MASH donor‐derived organoids showing higher susceptibility. Lipidomic profiling of MASH organoids closely resembles MASH liver biopsies.
Ekta Minocha, Ashwani Kumar Gupta, Nate Schmidt, Richard M. Green, John G. Purdy, Jason A. Wertheim   +5 more
wiley   +1 more source

Electrical‐Stimulation Hydrogel Electronic Skin for Sustainable Hybrid Biomechanical–Electromagnetic Energy Harvesting and Accelerating Wound Healing

Advanced Science, Volume 13, Issue 49, 3 September 2026.
A hybrid biomechanical–electromagnetic energy‐harvesting e‐skin is developed using a gelatin‐based outer matrix with a zwitterionic conductive inner layer. The e‐skin autonomously generates stable electrical stimulation from daily body motion and ambient electronics, enabling significantly enhanced wound healing bothin vitro and in vivo.
Syun‐Hong Chou, Ming‐Han Lu, Wei‐Chen Peng, Wei‐Chun Yang, Pei‐Yi Liu, Yu‐Hsuan Yang, Yi‐Lin Huang, Cheng‐Hung Tsai, Ting‐Yu Yang, Xuan Zhang, Zhi‐Xian Yan, Ying‐Chih Lai, San‐Yuan Chen   +12 more
wiley   +1 more source

Polarized microscopy with picrosirius red: potential for reproducible burn depth grading [PDF]

This research explores the challenges in accurately classifying burn severity and the limitations associated with traditional histology-based model training.
LaNguyen, Chantelle, Kennedy, Gordon T, Wakida, Nicole, Fox, Alexis M, Chin, Theresa, Rowland, Rebecca, Durkin, Anthony J, Campbell, Christopher A, Joe, Victor   +8 more
core   +1 more source

A Porcine Model of Intervertebral Disc Injury Recapitulates Human Discogenic Pain Via Notochordal Cell Loss and Pain‐Inducing Nucleus Pulposus Cell Emergence

JOR SPINE, Volume 9, Issue 3, September 2026.
A porcine model of disc injury recapitulates key clinical, histological, and molecular features of human discogenic low back pain. Multi‐omics analyses identify a shift from notochordal cells to pain‐associated nucleus pulposus cells as a potential driver of disease progression. ABSTRACT Background Lower back pain (LBP) is one of the most common causes
Giselle Kaneda, Jacob T. Wechsler, Melissa Chavez, Julia Sheyn, Karandeep Cheema, Chushu Shen, Dante Rigo De Righi, Lixia Wang, Yin‐Chen Hsu, Pablo Avalos, Yibin Xie, Wafa Tawackoli, Candace Floyd, Debiao Li, Dmitriy Sheyn   +14 more
wiley   +1 more source

Sustained Release and Therapeutic Evaluation of Simvastatin‐Loaded Bioglass–Chitosan Gel Formulation for Skin Regeneration and Wound Healing Potential

MedComm – Biomaterials and Applications, Volume 5, Issue 3, September 2026.
A multifunctional chitosan–gallic acid hydrogel incorporated with heparin modified Zn–Ag doped bioglass and simvastatin was synthesized for chronic wound healing. The system shows antioxidant, antimicrobial, and pro‐angiogenic properties, promoting cell proliferation and collagen production.
Durgesh Kumar, Suhela Tyeb, Baby Shruit Shukla, Vivek Verma, Nitesh Kumar   +4 more
wiley   +1 more source