Results 111 to 120 of about 3,539,899 (186)

Caloric restriction and aerobic exercise differentially counteract muscle–tendon dysfunction following diet‐induced obesity in C57BL/6J mice

The Journal of Physiology, EarlyView.
Abstract figure legend Diet‐induced obesity induced fibro‐adipogenic remodelling of the muscle–tendon unit, characterized by increased fibrosis, reduced specific force, impaired relaxation kinetics, elevated hysteresis, and reduced aerobic capacity and glucose tolerance.
Leonardo Cesanelli, Petras Minderis, Andrej Fokin, Aivaras Ratkevicius, Ingrida Balnyte, Polzonetti Valeria, Tomas Venckunas, Cameron Hill, Danguole Satkunskiene, Hans Degens   +9 more
wiley   +1 more source

Maternal protein restriction programs the ageing kidney: Proteomic signatures of early‐life origin renal and metabolic dysfunction

The Journal of Physiology, EarlyView.
Abstract figure legend Maternal protein restriction (MPR) induced persistent renal histopathological alterations accompanied by elevated serum creatinine levels. Nephron‐segment proteomic analysis revealed region‐specific molecular dysregulation affecting Bowman's capsule (PARK7, oxidative stress sensor; MSN, cytoskeletal organization), the proximal ...
Marina Pereira Pires, Matheus Naia Fioretto, Marcel Rodrigues Ferreira, Isabelle Tenori Ribeiro, Luísa Annibal Barata, Flávia Alessandra Maciel, Lucas Sobrinho Lemos, Renato Mattos, Luiz Marcos Frediane Portela, Patrick Vieira de Souza, Luisa Correia Gomes, Gustavo Monezzi Cordeiro, Wellerson Rodrigo Scarano, Patrícia Aline Boer, Jose Antonio Rocha Gontijo, Luis Antonio Justulin   +15 more
wiley   +1 more source

Quantification of collagen fibers in canine uteri treated with medroxyprogesterone acetate

Pesquisa Veterinária Brasileira
: Collagen plays essential roles in remodeling uterine tissue during decidualization, implantation, pregnancy and involution. To understand whether the progestational agent medroxyprogesterone acetate (MPA) can modify the organization and deposit of ...
Paulo Salinas, Maria A. Miglino, Mariano del Sol   +2 more
doaj   +1 more source

Robust quantitative assessment of collagen fibers with picrosirius red stain and linearly polarized light as demonstrated on atherosclerotic plaque samples. [PDF]

PLoS One, 2021
Greiner C, Grainger S, Farrow S, Davis A, Su JL, Saybolt MD, Wilensky R, Madden S, Sum ST.   +8 more
europepmc   +1 more source

β‐Caryophyllene Mitigates Thioacetamide‐Induced Liver Fibrosis Through CB2‐Mediated Suppression of Necroptosis: A Therapeutic Investigation

Pharmacology Research &Perspectives, Volume 14, Issue 5, October 2026.
β‐Caryophyllene is a multifunctional sesquiterpene with significant therapeutic potential. Our findings demonstrate that β‐caryophyllene exerts broad hepatoprotective effects through the activation of cannabinoid type 2 (CB2) receptors. These effects include suppression of oxidative stress–induced injury, attenuation of inflammatory responses ...
Lujain Bader Eddin, Seenipandi Arunachalam, Loay Lubbad, Fayez T. Hammad, Ernest Adeghate, Sandeep Subramanya, Shreesh Ojha   +6 more
wiley   +1 more source

A 3D‐Bioprinted, Cell‐Guiding Hydrogel Patch Promotes Functional Repair of Abdominal Incisions via Anisotropic ECM Remodeling

Smart Medicine, Volume 5, Issue 5, October 2026.
Abdominal incisions can heal into mechanically weak, disorganized scars. We developed a 3D‐bioprinted hydrogel patch with cell‐laden filaments oriented perpendicular to the incision, providing a guiding scaffold for local repair cells. This architecture supports organized collagen deposition and improves mechanical restoration of the healing abdominal ...
Tianxing Gong, Hao Li, Xueqiang Peng, Xinwei Liu, Xinyan Zhang, Qiushi Tang, Stephanie Willerth, Mario Taba Junior, Ricardo M. Carvalho, Hailong Yu, Shibo Wei, Hangyu Li   +11 more
wiley   +1 more source

Red SICTA. Informe de actividades - Fase I (Julio 2004 - Junio 2005) [PDF]

, 2005
El informe consta de dos partes. En la primera se describen las actividades llevadas a cabo por la Unidad Ejecutora del Proyecto (UEP) y se establece el grado de cumplimiento habido en relación al Plan de Acción del Proyecto (2004 – 2005), el cual ...
Proyecto Red de Innovación Agrícola (Red SICTA)
core  

From Collagen Colour to Collagen Biology: An Integrated Framework for Dermal Remodelling Assessment

Cosmetics
Age-related deterioration of the dermal extracellular matrix is driven primarily by fibroblast dysfunction, leading to loss of collagen integrity, elasticity, and structural support.
Francesco Marchetti, Matteo Basso, Giuseppe Colombo, Dissapong Panithaporn, Maurizio Cavallini   +4 more
doaj   +1 more source

Nanomaterial Strategies for Pulmonary Delivery of Immunotherapeutics in Lung Cancer Treatment

Advanced Healthcare Materials, Volume 15, Issue 34, 11 September 2026.
Inhalable immunotherapeutic nanomedicines enable organ‐selective immune modulation by overcoming pulmonary delivery barriers and concentrating therapy within lung tumors. This Review defines how nanomaterial properties govern airway deposition, retention, cellular partitioning, and immune activation across vaccines, checkpoint blockade, STING agonists,
Han Zhang, Wei Tang
wiley   +1 more source

MASH Background Confers Enhanced Disease Susceptibility and Acetaminophen Toxicity in iPSC‐Derived Liver Organoids

Advanced Science, Volume 13, Issue 53, 24 September 2026.
This work establishes a novel method for generating multicellular liver organoids from control and MASH donor iPSCs. The model recapitulates several disease‐specific characteristics, with MASH donor‐derived organoids showing higher susceptibility. Lipidomic profiling of MASH organoids closely resembles MASH liver biopsies.
Ekta Minocha, Ashwani Kumar Gupta, Nate Schmidt, Richard M. Green, John G. Purdy, Jason A. Wertheim   +5 more
wiley   +1 more source