Results 111 to 120 of about 13,325 (181)

Aspectos morfológicos da uretra de ratas após eletroestimulação do assoalho pélvico Morphological aspects of the urethra in female rats after electrical stimulation of the pelvic floor

open access: yesRevista Brasileira de Ginecologia e Obstetrícia, 2013
OBJETIVO: Avaliar os efeitos da eletroestimulação (ES) do assoalho pélvico na uretra de ratas. MÉTODOS: Quarenta ratas adultas foram distribuídas, randomicamente, em quatro grupos com dez animais cada: Ctrl - sem intervenção; Sham - não foi submetido a ...
Adriana Luciana Moreno Camargo   +5 more
doaj  

The effect of the irrigation solutions on dentin organic components: Pilot study

open access: yesЭндодонтия Today
INTRODUCTION. Tooth decay and its complications are prevalent dental issues among adults. Endodontic treatment is the standard of care for complicated caries, specifically pulpitis and periodontitis.
Z. S. Khabadze   +5 more
doaj   +1 more source

Nonlinear Imaging Allows to Characterize Granulomas and Fibrosis in Mice Tissue From Experimental Schistosomiasis

open access: yesJournal of Biophotonics, Volume 19, Issue 6, June 2026.
Second Harmonic Generation and Two‐Photon Excitation Fluorescence microscopy allows to characterize mice tissues infected with Schistosoma mansoni in an experimental model. ABSTRACT Schistosomiasis is a neglected disease caused by parasites of the genus Schistosoma that poses serious public health problems.
Gladystone Rocha da Fonseca   +6 more
wiley   +1 more source

Detrimental Effect of Low‐Magnitude High‐Frequency Vibration in an Ex Vivo Model of Intervertebral Disc Degeneration Despite Estrogen Treatment

open access: yesJOR SPINE, Volume 9, Issue 2, June 2026.
Low‐magnitude high‐frequency vibration (LMHFV), with or without 17β‐oestradiol (E2), exacerbated papain‐induced bovine intervertebral disc degeneration, reducing cell viability, impairing matrix production, and increasing inflammation. E2 showed no protective effect against papain‐induced degeneration or LMHFV.
Jan Ulrich Jansen   +9 more
wiley   +1 more source

Comparative Analysis of Dual‐miRNA Mediated Stimulation of Nucleus Pulposus and Bone Marrow Derived Stem Cells for Intervertebral Disc Repair

open access: yesJOR SPINE, Volume 9, Issue 2, June 2026.
Nucleus pulposus (NP) and bone marrow derived stem cells (BMSCs) transfected with miRNA‐149‐5p‐mimic and 221‐3p‐inhibitor were evaluated in goat monolayer, microtissue, and ex vivo organ cultures of mild degeneration. miRNA‐treated NP cells demonstrated an anti‐catabolic and pro‐discogenic response in organs, highlighting its potential as a ...
Tara Ní Néill   +7 more
wiley   +1 more source

Defining the Human Nucleus Pulposus Microenvironment and Its Impact on Cell Matrix Synthesis and Metabolic Activity

open access: yesJOR SPINE, Volume 9, Issue 2, June 2026.
Human intervertebral disc nutrient microenvironment. Changes observed in microenvironmental profile as a result of degeneration outlined on upper vertebral body with ranges of each species as reported in previous studies. Oxygen, glucose, and lactate gradients are profiled across the lower disc in both healthy and degenerated states.
Niamh Wilson   +6 more
wiley   +1 more source

Preclinical Efficacy and Safety Study of a Novel Dermal Fibroblast Modulating Drug, SLI‐F06, in Cutaneous Wound Healing

open access: yesMedComm, Volume 7, Issue 6, June 2026.
A novel, chemically synthesized fibromodulin (FMOD)‐derived peptide, SLI‐F06, has been developed to significantly improve scar appearance, tensile strength, and histological outcomes among multiple preclinical animal models. Demonstrating no genotoxicity or systemic/local toxicity, SLI‐F06 has received United States Food and Drug Administration ...
Zhong Zheng   +9 more
wiley   +1 more source

Structural Characterization of Cardiac Free‐Running Purkinje Fibers Using Inhomogeneous Magnetization Transfer (ihMT): A Proof of Concept MRI‐Histology Approach

open access: yesNMR in Biomedicine, Volume 39, Issue 6, June 2026.
The cardiac Purkinje network is essential for synchronized ventricular activation but remains difficult to visualize with conventional MRI due to limited structural contrast. This study demonstrates that inhomogeneous magnetization transfer imaging provides enhanced contrast that differentiates free‐running Purkinje fibers, Purkinje‐Myocardial Junction,
Arash Forodighasemabadi   +11 more
wiley   +1 more source

Comparative study of clinicofunctional staging of oral submucous fibrosis with qualitative analysis of collagen fibers under polarizing microscopy

open access: yesIndian Journal of Dental Research, 2009
Objective : The aim of the study was to assess the severity of the disease in oral submucous fibrosis (OSF), correlate the clinical, functional staging with histopathological staging, and analyze collagen distribution in different stages of OSF using the
Ceena Denny   +3 more
doaj  

Mitochondrial Transplantation as a New Therapeutic Approach Against Cardiac and Renal Consequences in Male Rats With Myocardial Infarction

open access: yesActa Physiologica, Volume 242, Issue 6, June 2026.
ABSTRACT Aim Myocardial infarction (MI) is one of the leading causes of death worldwide. MI is associated with cardiac structural and functional alterations. Among these, cardiac fibrosis may be significantly influenced by mitochondrial dysfunction. We sought to evaluate whether the injection of functional mitochondria from healthy muscle could improve
María Cuesta‐Corral   +13 more
wiley   +1 more source

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