Results 161 to 170 of about 992,973 (322)

Pharmacokinetic modelling of intravenous immunoglobulin in children with primary immunodeficiencies and secondary antibody deficiencies

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Children with primary immunodeficiency (PID) and secondary antibody deficiency (SAD) often require immunoglobulin replacement therapy due to low plasma immunoglobulin G (IgG) levels and recurrent infections. Existing pharmacokinetic models for immunoglobulin in PID patients predominantly focus on adults, with limited attention to ...
Iek Leng Cheng   +4 more
wiley   +1 more source

Lab‐Scale Continuous Biomanufacturing: A Tool for Process Development With Adaptive Strategies for Capture and Virus Inactivation

open access: yesBiotechnology and Bioengineering, EarlyView.
Schematic representation of the continuous lab‐scale process. ABSTRACT Monoclonal antibodies (mAbs) are nowadays fundamental in treating a wide range of severe diseases, including cancer, infections, or autoimmune disorders. Due to their high specificity, potent activity, and fewer side effects compared to small molecular drugs, the market for mAbs is ...
Thomas Kruse   +5 more
wiley   +1 more source

Boards and ESG Performance: The Contingent Influence of Climate Vulnerability on Global Banks

open access: yesBusiness Strategy and the Environment, EarlyView.
ABSTRACT This study examines the contingent effect of climate vulnerability on the relationship between board characteristics and environmental, social, and governance (ESG) performance of global banks. We use a dataset of 438 banks across 54 countries (2010–2022) and fixed effects estimation, two‐stage least squares, and generalized method of moments ...
Renata Karkowska   +3 more
wiley   +1 more source

Modeling and simulation of the control system for the plane mirror rotating interferometer

open access: yesEngineering Reports
To solve the problem of optical path difference velocity (OPDV) stability in the Fourier spectrometer, a Cerebellar Model Articulation Controller‐Proportional‐Integral‐Derivative (CMAC‐PID) composite control strategy is proposed. The relationship between
Yusheng Qin   +4 more
doaj   +1 more source

Dynamic pH profiles drive higher cell‐specific and volumetric productivity

open access: yesBiotechnology Progress, EarlyView.
Implementation of dyamic pH profiles for increased CHO cell culture productivity. Abstract Mammalian cell cultures in bioreactors rely heavily on critical process parameter control to ensure optimal growth, productivity, and reproducibility to produce recombinant therapeutic proteins. Culture pH has been shown to be a critical parameter that influences
Stephanie R. Klaubert   +6 more
wiley   +1 more source

Interface Engineering Remarkably Improves the Stability of Fe‐Based Electrode for Alkaline Water Electrolysis at Industrial Ampere‐Level Current Density

open access: yesCarbon Energy, EarlyView.
Interface engineering improves the stability of iron‐based industrial oxygen evolution catalysts by more than 2000 times at ampere‐level current density. ABSTRACT Iron‐based self‐supported electrocatalysts offer cost‐effective oxygen evolution activity but suffer from severe stability degradation under industrial operation.
Chunfa Liu   +10 more
wiley   +1 more source

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