Results 91 to 100 of about 4,923,870 (255)
Expression of toll-like receptor negative regulators in porcine intestinal epithelial (PIE) cells.
, 2013 PIE cells were pre-treated with different bacterial strains for 48 h, stimulated with heat-stable ETEC PAMPs, and the expression of IRAK-M, SIGIRR, Bcl-3, MKP-1, Tollip, and A20 negative regulators was studied at the indicated time points.
Eriko Chiba (394695) +9 more
core +1 more source
Advanced Science, EarlyView.In the post‐stroke brain, Foxa2 induces the transcriptional upregulation of Nrsn1 in NSCs. Nrsn1 functionally couples with Smarcc1, modulating its nuclear availability and protein abundance, thereby influencing Smarcc1‐associated regulatory programs linked to neuronal lineage commitment. Through this coupling, Nrsn1 promotes the differentiation of NSCs
Ruolin Zhang +18 more
wiley +1 more source
Aplicación de estudios radiológicos para el diagnóstico de patologías comunes en el pie diabético
, 2017 Precisar cuál es la aplicación de la Radiología en el diagnostico y tratamiento de las patologías comunes en el pie diabético; ya que la diabetes es actualmente una de las enfermedades con mayor índice de mortalidad a nivel mundial, además es la ...
Ramírez Buitrago, Angela María +1 more
core
FOXP1 Knockdown Reprograms Th9 CAR‐T Cells to Overcome Antigen Escape
Advanced Science, EarlyView.FOXP1 knockdown enhances Th9 CAR‐T cell function by promoting IL‐9 production, effector activation, and reduced exhaustion. Reprogrammed Th9 CAR‐T cells strengthen direct tumor killing and activate endogenous antitumor immunity through dendritic cells and CD8+ T cells, thereby suppressing both antigen‐positive and antigen‐loss tumor growth and ...
Yihan Zhu +14 more
wiley +1 more source
Advanced Science, EarlyView.The graphical abstract illustrates that sublethal thermal stress after iRFA upregulates the chaperone CRYAB in residual HCC cells, which stabilizes β‐catenin and drives a dual pathological program, including EMT and N2‐TAN polarization, thereby leading to heterotypic CTC cluster formation. The MMP‐9‐responsive hydrogel (XB@Gel) delivers XAV‐939 and BMS‐
Hui Chen +8 more
wiley +1 more source
, 1958 Video footage from the WBAP-TV station in Fort Worth, Texas to accompany a news story about a work setting, in which the workers get to smash a pie into their boss's face for a very good cause.
WBAP-TV (Television station : Fort Worth, Tex.)
core
Advanced Science, EarlyView.Phase separation of SF3B1 acts as a key regulatory mechanism for dynamic alternative splicing throughout early mouse embryogenesis. Its absence triggers extensive splicing errors, which induce persistent DNA damage, defective cell cycle progression, and failed cell lineage commitment, and ultimately hinder the normal growth and development of ...
Kang Zhao +15 more
wiley +1 more source
Mandement épiscopal de Mgr. de Lenzbourg, imprimé sans mention de date, daté à la main lors de l'expédition aux diverses paroissesContient également la traduction française du bref du pape Pie VI accordant une indulgence plénière aux fidèles qui ...
Lenzbourg, Bernard Emmanuel de
core +1 more source
Abstract Representation of Movement Parameters in Basal Ganglia Output
Advanced Science, EarlyView.The basal ganglia output provides a scalable velocity/position signal across behavioral contexts, supporting the idea that these variables are represented in the brain as abstract entities rather than as fixed changes in joint angles or specific sets of body effectors.
Ana Silvia Báez‐Cordero +3 more
wiley +1 more source
Advanced Science, EarlyView.Sepsis triggers hippocampal SIRT7 loss, promoting histone H2B succinylation and activation of the PD‐1/PD‐L1–PINK1 axis. This metabolic‐epigenetic cascade drives aberrant mitophagy and neuronal injury, ultimately causing cognitive deficits. Targeting SIRT7‐dependent succinylation offers a potential strategy to protect brain function during sepsis ...
Na Meng +12 more
wiley +1 more source