Results 181 to 190 of about 4,923,870 (255)

Machine Learning Models of Phase Contrast Images Predict Efficiency of Human Pluripotent Stem Cell Differentiation to Cardiomyocytes

Biotechnology and Bioengineering, EarlyView.
Human pluripotent stem cells were differentiated to cTnT+ cardiomyocytes and imaged throughout the process using phase contrast. We predicted differentiation efficiency (cTnT+ area) from phase contrast and compared model performance with a live‐cell cTnT‐GFP reporter.
Austin K. Feeney, Yaniv Ovadia, Aaron D. Simmons, Christian Elabd, Claire J. Peplinski, Frank Li, Sean P. Palecek   +6 more
wiley   +1 more source

Conserved CD4 T-cell responses correlate with antibody neutralization in solid organ transplant recipients after bivalent SARS-CoV-2 vaccination. [PDF]

Front Immunol
Stavrakis G, Roznik K, Stoddart L, Johnston TS, Panda S, Hage C, Teles AT, Eby Y, Werbel WA, Tobian AAR, Milstone AM, Sette A, Grifoni A, Karaba AH, Thompson EA, Cox AL.   +15 more
europepmc   +1 more source

Scale‐Down Platforms for Process‐Oriented Enzyme Screening Using Microfluidics

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Enzyme screening platforms are typically evaluated based on their throughput and analytical performance rather than their ability to mimic the conditions encountered at large scale. In bioreactors, enzymes experience gradients in substrate concentration, oxygen availability, pH, temperature, and interfacial exposure, caused by imperfect mixing
Maria I. Rodriguez‐Torres, Elif Erdem, Junhyeong Wang, Ulrich Krühne, Michael Daniele, John M. Woodley   +5 more
wiley   +1 more source

Barrier immune memory is programmed by intestinal epithelial cell presentation of cytosol-delivered bacterial antigens. [PDF]

Nat Immunol
Wilson CG, Acharya MP, Karsch L, Duck LW, Twumasi-Ankrah N, Wang Y, Shen H, Frey BF, McKee AR, Oza VH, Harbour SN, Nagaoka-Kamata Y, Singer JR, Hatton RD, Moffitt J, Gunzer M, Zindl CL, Weaver CT.   +17 more
europepmc   +1 more source

Hyperbranched poly‐L‐lysine surface‐engineered bioprosthetic heart valves with anti‐calcification, anti‐infection, and durability

BMEMat, EarlyView.
The challenges of bioprosthetic heart valves (BHV) with respect to calcification, infection, and poor durability are tackled by surface engineering of hyperbranched poly‐L‐lysine (HBPL), providing a translational solution to improve long‐term valve performance.
Pai Peng, Dongchao Qiu, Yongyuan Kang, Qiaoxuan Wang, Xuelong Wang, Boyana Parvanova, Miroslav Karabaliev, Changyou Gao   +7 more
wiley   +1 more source

Distinct Transcriptomic Profiles in ART-Treated People With HIV Are Associated With NF-κB-Regulated Gene Expression and Inflammatory Cytokine Signatures. [PDF]

J Acquir Immune Defic Syndr
Wang Y, Gornalusse GG, Bhatt U, Siegel DA, Barbehenn A, Hoh R, Martin J, Hecht F, Pilcher C, Semenova L, Murdoch DM, Margolis DM, Levy CN, Jerome KR, Rudin CD, Hladik F, Deeks SG, Lee SA, Browne EP.   +18 more
europepmc   +1 more source

Review of the fauna associated with wild and farmed mussels and oysters in the Mediterranean

Biological Reviews, EarlyView.
ABSTRACT Mussels and oysters are important ecosystem engineers which modify the physical and chemical characteristics of the environment and create habitats that support highly diverse associated communities. In the Mediterranean Sea, the native Mediterranean mussel Mytilus galloprovincialis and the European flat oyster Ostrea edulis, together the ...
Barbara Mikac, Marina Antonia Colangelo, Alessandro Tarullo, Marco Abbiati, Eugenio Fossi, Federica Costantini   +5 more
wiley   +1 more source

Clinical Anatomy of the Left and Right Atrial Appendages in Humans: Comparative and Developmental Perspective

Clinical Anatomy, EarlyView.
ABSTRACT Human atrial chambers derive from distinct embryonic anlagens, the original embryonic atria gradually transforming into the so‐called auricles, or atrial appendages. This study quantifies macroscopic variations in pectinate muscle architecture in human atrial appendages and evaluates their visualization using clinical imaging modalities.
Markéta Lexová, Caroline Neradilová, Jan Kovanda, Jan Burkert, Jiří Beneš Jr., Martin Bartos, Theodor Adla, Vojtech Melenovsky, Alena Kvasilova, Ondrej Fabian, Ondrej Naňka, David Sedmera   +11 more
wiley   +1 more source

Altered MAIT cell activation characteristics with impaired IL-10 and IL-17A response programs in active Crohn's disease. [PDF]

J Immunol
Mouchtaridi E, Halfvarson J, Mak JYW, Fairlie DP, Mjösberg J, Bergman P, Sandberg JK, Boulouis C.   +7 more
europepmc   +1 more source

Donor‐To‐Recipient Mean Axonal Count Ratios of Upper Limb Nerves Used in Nerve Transfer Surgery: A Systematic Review of Histomorphometric Cadaveric Studies

Clinical Anatomy, EarlyView.
ABSTRACT Nerve transfer surgery may be performed to restore sensorimotor function following peripheral nerve trauma or dysfunction. There is biological plausibility and limited correlative evidence that donor‐to‐recipient axon count ratios may impact functional outcomes.
Samuel James Ng, Rosa Morgan‐Young, Alexander Laing, Rebecca Molden, Suzanne Thomson   +4 more
wiley   +1 more source