Results 41 to 50 of about 4,923,870 (255)

Effect of pie clones on cell size and orientation.

, 2016
A, pie homozygous clones lacking GFP. Cells outlined with anti-Dlg (magenta). B, Anti-Dlg labeling from panel A. The scattered cells with large apical profiles are mitotic cells, whose cell body rises apically to divide in the plane of the junctions.
Gerard Rimesso (3605129), Nicholas E. Baker (117151), Abhijit Kale (117142)   +2 more
core   +1 more source

PIE-QG: Paraphrased Information Extraction for Unsupervised Question Generation from Small Corpora

, 2022
PIE-QG: Paraphrased Information Extraction for Unsupervised Question Generation from Small ...
Dinesh Nagumothu (13067094), Bahadorreza Ofoghi (13059933), Peter Eklund (13068615), Guangyan Huang (13072050)   +3 more
core   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

Autoimmune Comorbidities as Modifiers of Phenotypic Heterogeneity in Facioscapulohumeral Dystrophy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral dystrophy type 1 (FSHD1) shows clinical heterogeneity that is only partly explained by D4Z4 repeat unit (RU) size. Although immune and inflammatory mechanisms may contribute to disease variability, the prevalence and clinical impact of autoimmune diseases in FSHD remain unclear.
Jonathan Pini, Giulia Tammam, Andra Ezaru, Manuela Gambella, Benoît Sanson, Luisa Villa, Michele Cavalli, Mihai‐Bogdan Ioncea, Angela Puma, Sabrina Sacconi   +9 more
wiley   +1 more source

Genetic Association of the Porcine C9 Complement Component with Hemolytic Complement Activity [PDF]

Asian-Australasian Journal of Animal Sciences, 2015
The complement system is a part of the natural immune regulation mechanism against invading pathogens. Complement activation from three different pathways (classical, lectin, and alternative) leads to the formation of C5-convertase, an enzyme for ...
D. V. A. Khoa, K. Wimmers
doaj   +1 more source

Dynamically Actuated Reconfigurable Topographical Surface Enables Active Control of Implant‐Associated Infections

Advanced Functional Materials, EarlyView.
A dynamically actuated reconfigurable topographical surface (DARTS) integrates contact‐mediated bactericidal nanotopography with programmable mechanical actuation to actively disrupt bacterial biofilms. Dynamic surface reconfiguration enhances bacterial killing and suppresses implant‐associated infections in vivo, providing a new strategy for active ...
Mohammad Asadi Tokmedash, Jihun Lee, J. Scott VanEpps, Sungmin Nam, Jouha Min   +4 more
wiley   +1 more source

Teleoperación de robots para centrales nucleares. Una arquitectura genérica de software. [PDF]

, 2000
Los sistemas de teleoperación utilizados hasta el momento en las operaciones de mantenimiento de centrales nucleares no son flexibles, siendo necesario el diseño de un software que soporte un proceso de adaptación rápida para facilitar el desarrollo de ...
Alonso, Alejandro, de la Puente, Juan Antonio, Marín García, Fulgencio, Pastor Franco, Juan Ángel, Álvarez Torres, María Bárbara   +4 more
core   +1 more source

An Epigenetic Fate Converter Based on Nuclei‐Targeting Lipid Nanoparticles Drives Neuronal Programming of Stem Cells for Spinal Cord Repair

Advanced Functional Materials, EarlyView.
Schematic illustration of LNP‐MPG nuclei‐targeting delivery of HMW‐FGF2 promoting histone acetylation to regulate the fate of DPSCs and treat spinal cord injury. LNPs components include pHMW‐FGF2 plasmid, DSPC, Dlin‐MC3‐DMA, cholesterol, and PEG2000, and are modified with MPG to form HMW‐FGF2@LNP‐MPG (HLM). HLM nuclei‐targets DPSCs to deliver HMW‐FGF2,
Heng Zhou, Qiang Qin, Xiqin Li, Hanyu Ding, Chun Xu, Yan He, Qingsong Ye   +6 more
wiley   +1 more source

In vitro evaluation of the immunomodulatory and wakame assimilation properties of Lactiplantibacillus plantarum strains from swine milk

Frontiers in Microbiology
The emergence and spread of antibiotic resistance threat forced to explore alternative strategies for improving the resistance to pathogens in livestock production. Probiotic lactic acid bacteria represent an alternative for this objective. In this study,
Ryusuke Ohgi, Sudeb Saha, Sudeb Saha, Binghui Zhou, Binghui Zhou, Taiga Sakuma, Mitsuki Sakurai, Yuhka Nakano, Fu Namai, Fu Namai, Wakako Ikeda-Ohtsubo, Wakako Ikeda-Ohtsubo, Yoshihito Suda, Keita Nishiyama, Keita Nishiyama, Julio Villena, Julio Villena, Haruki Kitazawa, Haruki Kitazawa   +18 more
doaj   +1 more source

Therapeutic interaction of systemically-administered mesenchymal stem cells with peri-implant mucosa.

PLoS ONE, 2014
ObjectivesThe objective of this study was to investigate the effect of systemically transplanted mesenchymal stem cells (MSCs) on the peri-implant epithelial sealing around dental implants.Materials and methodsMSCs were isolated from bone marrow of donor
Ryosuke Kondo, Ikiru Atsuta, Yasunori Ayukawa, Takayoshi Yamaza, Yuri Matsuura, Akihiro Furuhashi, Yoshihiro Tsukiyama, Kiyoshi Koyano   +7 more
doaj   +1 more source