Results 21 to 30 of about 4,923,870 (255)

Pie-chart showing the ratio of site-types.

, 2021
Pie-chart showing the ratio of site-types.
Nikolaus Boroffka (11636654), Mehmet Karaucak (11636651), Daniel Steiniger (6576908)   +2 more
core   +1 more source

Exopolysaccharides From Streptococcus thermophilus ST538 Modulate the Antiviral Innate Immune Response in Porcine Intestinal Epitheliocytes

Frontiers in Microbiology, 2020
It was reported that exopolysaccharides (EPSs) from lactobacilli are able to differentially modulate mucosal antiviral immunity. Although research has described the ability of EPSs derived from Streptococcus thermophilus to modulate the mucosal immune ...
Hiroya Mizuno, Hiroya Mizuno, Kae Tomotsune, Kae Tomotsune, Md. Aminul Islam, Md. Aminul Islam, Ryutaro Funabashi, Ryutaro Funabashi, Leonardo Albarracin, Leonardo Albarracin, Leonardo Albarracin, Wakako Ikeda-Ohtsubo, Wakako Ikeda-Ohtsubo, Hisashi Aso, Hisashi Aso, Hideki Takahashi, Hideki Takahashi, Katsunori Kimura, Julio Villena, Julio Villena, Yasuko Sasaki, Haruki Kitazawa, Haruki Kitazawa   +22 more
doaj   +1 more source

Selection of Immunobiotic Ligilactobacillus salivarius Strains from the Intestinal Tract of Wakame-Fed Pigs: Functional and Genomic Studies

Microorganisms, 2020
In this article, Ligilactobacillus salivarius FFIG strains, isolated from the intestinal tract of wakame-fed pigs, are characterized according to their potential probiotic properties.
Binghui Zhou, Leonardo Albarracin, Yuhki Indo, Lorena Arce, Yuki Masumizu, Mikado Tomokiyo, Md. Aminul Islam, Valeria Garcia-Castillo, Wakako Ikeda-Ohtsubo, Tomonori Nochi, Hidetoshi Morita, Hideki Takahashi, Shoichiro Kurata, Julio Villena, Haruki Kitazawa   +14 more
doaj   +1 more source

Efficient circular RNA engineering by end-to-end self-targeting and splicing reaction using Tetrahymena group I intron ribozyme

Molecular Therapy: Nucleic Acids, 2023
Circular RNA (circRNA) has various advantages over linear mRNA that is gaining success as a new vaccine and therapeutic agent. Thus, circRNA and its engineering methods have attracted attention recently. In this study, we developed a new in vitro circRNA
Kyung Hyun Lee, Seongcheol Kim, Jaehwi Song, Seung Ryul Han, Ji Hyun Kim, Seong-Wook Lee   +5 more
doaj   +1 more source

Immunobiotic lactic acid bacteria beneficially regulate immune response triggered by poly(I:C) in porcine intestinal epithelial cells

Veterinary Research, 2011
This study analyzed the functional expression of TLR3 in various gastrointestinal tissues from adult swine and shows that TLR3 is expressed preferentially in intestinal epithelial cells (IEC), CD172a+CD11R1high and CD4+ cells from ileal Peyer's patches ...
Hosoya Shoichi, Villena Julio, Shimazu Tomoyuki, Tohno Masanori, Fujie Hitomi, Chiba Eriko, Shimosato Takeshi, Aso Hisashi, Suda Yoshihito, Kawai Yasushi, Saito Tadao, Alvarez Susana, Ikegami Shuji, Itoh Hiroyuki, Kitazawa Haruki   +14 more
doaj   +1 more source

Clinical and transcriptomic features of persistent exacerbation‐prone severe asthma in U‐BIOPRED cohort

Clinical and Translational Medicine, 2022
Background Exacerbation‐prone asthma is a feature of severe disease. However, the basis for its persistency remains unclear. Objectives To determine the clinical and transcriptomic features of frequent exacerbators (FEs) and persistent FEs (PFEs) in the ...
Uruj Hoda, Stelios Pavlidis, Aruna T. Bansal, Kentaro Takahashi, Sile Hu, Francois Ng Kee Kwong, Christos Rossios, Kai Sun, Pankaj Bhavsar, Matthew Loza, Frederic Baribaud, Pascal Chanez, Stephen J. Fowler, Ildiko Horvath, Paolo Montuschi, Florian Singer, Jacek Musial, Barbro Dahlen, Norbert Krug, Thomas Sandstrom, Dominic E. Shaw, Rene Lutter, Louise J. Fleming, Peter H. Howarth, Massimo Caruso, Ana R. Sousa, Julie Corfield, Charles Auffray, Bertrand De Meulder, Diane Lefaudeux, Sven‐Erik Dahlen, Ratko Djukanovic, Peter J. Sterk, Yike Guo, Ian M. Adcock, Kian Fan Chung, the U‐BIOPRED study group   +36 more
doaj   +1 more source

Lactiplantibacillus plantarum Strains Modulate Intestinal Innate Immune Response and Increase Resistance to Enterotoxigenic Escherichia coli Infection

Microorganisms, 2022
Currently, probiotic bacteria with not transferable antibiotic resistance represent a sustainable strategy for the treatment and prevention of enterotoxigenic Escherichia coli (ETEC) in farm animals.
Ayelen Baillo, Julio Villena, Leonardo Albarracín, Mikado Tomokiyo, Mariano Elean, Kohtaro Fukuyama, Sandra Quilodrán-Vega, Silvina Fadda, Haruki Kitazawa   +8 more
doaj   +1 more source

Paraimmunobiotic Bifidobacteria Modulate the Expression Patterns of Peptidoglycan Recognition Proteins in Porcine Intestinal Epitheliocytes and Antigen Presenting Cells

Cells, 2019
Peptidoglycan recognition proteins (PGLYRPs) are a family of pattern recognition receptors (PRRs) that are able to induce innate immune responses through their binding to peptidoglycan (PGN), lipopolysaccharide, or lipoteichoic acid, or by interacting ...
Hikaru Iida, Masanori Tohno, Md. Aminul Islam, Nana Sato, Hisakazu Kobayashi, Leonardo Albarracin, AKM Humayun Kober, Wakako Ikeda-Ohtsubo, Yoshihito Suda, Hisashi Aso, Tomonori Nochi, Ayako Miyazaki, Hirohide Uenishi, Noriyuki Iwabuchi, Jin-zhong Xiao, Julio Villena, Haruki Kitazawa   +16 more
doaj   +1 more source

Efficient Selection of New Immunobiotic Strains With Antiviral Effects in Local and Distal Mucosal Sites by Using Porcine Intestinal Epitheliocytes

Frontiers in Immunology, 2020
Previously, we evaluated the effect of the immunobiotic strain Lactobacillus rhamnosus CRL1505 on the transcriptomic response of porcine intestinal epithelial (PIE) cells triggered by the challenge with the Toll-like receptor 3 (TLR-3) agonist poly(I:C ...
Leonardo Albarracin, Leonardo Albarracin, Valeria Garcia-Castillo, Valeria Garcia-Castillo, Yuki Masumizu, Yuhki Indo, Md Aminul Islam, Yoshihito Suda, Apolinaria Garcia-Cancino, Hisashi Aso, Hisashi Aso, Hideki Takahashi, Hideki Takahashi, Haruki Kitazawa, Haruki Kitazawa, Julio Villena, Julio Villena   +16 more
doaj   +1 more source

PIE-1 is required for transcriptional repression in proximal oocytes.

, 2023
A. N2 animals were treated with either control or pie-1 RNAi. Gonads were dissected from these animals and were fixed and stained for DNA (blue) and RNAPIIpSer2 (red). Depletion of PIE-1 results in persisting RNAPIIpSer2 signal in proximal oocytes.
Emilie Chien (16632457), W. Matthew Michael (3211092), Mezmur D. Belew (16632454)   +2 more
core   +1 more source