Results 51 to 60 of about 158,569 (182)

Characterization of Sirt2 using conditional RNAi in mice [PDF]

, 2011
Within the past eight years, RNA interference (RNAi) has emerged as a powerful experimental tool for gene function analysis in mice. Reversible control of shRNA mediated RNAi has been achieved by using a tetracycline (tet)-inducible promoter.
Reiss, Martina
core  

Prediction of two-phase flow through a safety relief valve [PDF]

, 2012
Safety relief valves are necessary elements in any pressurised system. The flow inside the safety relief valve shows a number of interesting, yet complicated, features especially when a two-phase flow is involved.
Dempster, William, Elmayyah, Wael
core   +1 more source

Spherical complexes attached to symplectic lattices [PDF]

, 2010
To the integral symplectic group Sp(2g,Z) we associate two posets of which we prove that they have the Cohen-Macaulay property. As an application we show that the locus of marked decomposable principally polarized abelian varieties in the Siegel space of
Looijenga, Eduard, van der Kallen, Wilberd   +1 more
core   +10 more sources

The secreted protein Cowpox Virus 14 contributes to viral virulence and immune evasion by engaging Fc-gamma-receptors.

PLoS Pathogens, 2022
The genome of cowpoxvirus (CPXV) could be considered prototypical for orthopoxviridae (OXPV) since it contains many open reading frames (ORFs) absent or lost in other OPXV, including vaccinia virus (VACV).
Ravi F Iyer, David M Edwards, Philipp Kolb, Hans-Peter Raué, Chris A Nelson, Megan L Epperson, Mark K Slifka, Jeffrey C Nolz, Hartmut Hengel, Daved H Fremont, Klaus Früh   +10 more
doaj   +1 more source

Global research trends of steroid-induced osteonecrosis of the femoral head: A 30-year bibliometric analysis

Frontiers in Endocrinology, 2022
ObjectiveTo explore the global research trends and hotspots of steroid-induced osteonecrosis of the femoral head (SONFH) through qualitative and quantitative analysis of bibliometrics.MethodsAll publications on SONFH published from 1992 to 2021 were ...
Chao Lu, Haodong Qi, Haodong Qi, Hanbo Xu, Hanbo Xu, Yangquan Hao, Zhi Yang, Wenxing Yu, Peng Xu   +8 more
doaj   +1 more source

Broad role for YBX1 in defining the small noncoding RNA composition of exosomes. [PDF]

, 2017
RNA is secreted from cells enclosed within extracellular vesicles (EVs). Defining the RNA composition of EVs is challenging due to their coisolation with contaminants, lack of knowledge of the mechanisms of RNA sorting into EVs, and limitations of ...
Lambowitz, Alan M, Nottingham, Ryan M, Qin, Yidan, Schekman, Randy, Shurtleff, Matthew J, Temoche-Diaz, Morayma M, Yao, Jun   +6 more
core   +1 more source

In vitro evaluation of the immunomodulatory and wakame assimilation properties of Lactiplantibacillus plantarum strains from swine milk

Frontiers in Microbiology
The emergence and spread of antibiotic resistance threat forced to explore alternative strategies for improving the resistance to pathogens in livestock production. Probiotic lactic acid bacteria represent an alternative for this objective. In this study,
Ryusuke Ohgi, Sudeb Saha, Sudeb Saha, Binghui Zhou, Binghui Zhou, Taiga Sakuma, Mitsuki Sakurai, Yuhka Nakano, Fu Namai, Fu Namai, Wakako Ikeda-Ohtsubo, Wakako Ikeda-Ohtsubo, Yoshihito Suda, Keita Nishiyama, Keita Nishiyama, Julio Villena, Julio Villena, Haruki Kitazawa, Haruki Kitazawa   +18 more
doaj   +1 more source

Immunoregulatory Effects Triggered by Lactic Acid Bacteria Exopolysaccharides: New Insights into Molecular Interactions with Host Cells

Microorganisms, 2016
Researchers have demonstrated that lactic acid bacteria (LAB) with immunomodulatory capabilities (immunobiotics) exert their beneficial effects through several molecules, including cell wall, peptidoglycan, and exopolysaccharides (EPS), that are able to ...
Jonathan Laiño, Julio Villena, Paulraj Kanmani, Haruki Kitazawa   +3 more
doaj   +1 more source

Serine one-carbon catabolism with formate overflow [PDF]

, 2016
Serine catabolism to glycine and a one-carbon unit has been linked to the anabolic requirements of proliferating mammalian cells. However, genome-scale modeling predicts a catabolic role with one-carbon release as formate. We experimentally prove that in
Athineos, Dimitris, Blyth, Karen, Gottlieb, Eyal, Kamphorst, Jurre J., Labuschagne, Christiaan Fred, Mackay, Gillian M., Maddocks, Oliver, Meiser, Johannes, Tumanov, Sergey, Van Den Broek, Niels, Vazquez, Alexei, Vousden, Karen   +11 more
core   +1 more source

Evaluation of the Immunomodulatory Activities of the Probiotic Strain Lactobacillus fermentum UCO-979C

Frontiers in Immunology, 2019
Lactobacillus fermentum UCO-979C, a strain isolated from a human stomach, was previously characterized by its potential probiotic properties. The UCO-979C strain displayed the ability to beneficially regulate the innate immune response triggered by ...
Valeria Garcia-Castillo, Valeria Garcia-Castillo, Valeria Garcia-Castillo, Ryoya Komatsu, Ryoya Komatsu, Patricia Clua, Yuhki Indo, Yuhki Indo, Michihiro Takagi, Michihiro Takagi, Susana Salva, Md. Aminul Islam, Md. Aminul Islam, Md. Aminul Islam, Susana Alvarez, Hideki Takahashi, Hideki Takahashi, Apolinaria Garcia-Cancino, Haruki Kitazawa, Haruki Kitazawa, Julio Villena, Julio Villena   +21 more
doaj   +1 more source