Results 111 to 120 of about 5,132 (198)
Sodium Channels and Mammalian Sensory Mechanotransduction [PDF]
, 2012 Background: Members of the degenerin/epithelial (DEG/ENaC) sodium channel family are mechanosensors in C elegans, and Nav1.7 and Nav1.8 voltage-gated sodium channel knockout mice have major deficits in mechanosensation.
Edith Hummler +7 more
core +4 more sources
A dietary fatty acid counteracts neuronal mechanical sensitization
Nature Communications, 2020 PIEZO2 is a critical component of the mechanism by which innocuous touch causes pain (tactile allodynia). Here, authors find that the dietary fatty acid margaric acid decreases PIEZO2 function in a dose-dependent manner and counteracts neuronal ...
Luis O. Romero +5 more
doaj +1 more source
European Journal of Pain, Volume 30, Issue 2, February 2026.ABSTRACT Background Machine learning (ML) is increasingly used to analyse pain‐related data, emphasising how well variables classify individuals, that is, training an algorithm to assign people to predefined groups such as high versus low pain sensitivity, rather than focusing on p‐values.
Jörn Lötsch +2 more
wiley +1 more source
Connections between the facial and trigeminal nerves: Anatomical basis for facial muscle proprioception [PDF]
, 2017 Proprioception is a quality of sensibility that originates in specialized sensory organs (proprioceptors) that inform the central nervous system about static and dynamic conditions of muscles and joints.
Cobo Díaz, Juan Luis +4 more
core +3 more sources
Etiology and Pharmacology of Neuropathic Pain [PDF]
, 2018 Injury to or disease of the nervous system can invoke chronic and sometimes intractable neuropathic pain. Many parallel, interdependent, and time-dependent processes, including neuroimmune interactions at the peripheral, supraspinal, and spinal levels ...
Alles, SRA, Smith, PA
core +1 more source
Cell Reports, 2019 Summary: A major challenge in biology is to link cellular and molecular variations with behavioral phenotypes. Here, we studied somatosensory neurons from a panel of bird species from the family Anatidae, known for their tactile-based foraging behavior ...
Eve R. Schneider +6 more
doaj +1 more source
On the Mechanism of Human Red Blood Cell Longevity: Roles of Calcium, the Sodium Pump, PIEZO1, and Gardos Channels [PDF]
, 2017 In a healthy adult, the transport of O2 and CO2 between lungs and tissues is performed by about 2 · 1013 red blood cells, of which around 1.7 · 1011 are renewed every day, a turnover resulting from an average circulatory lifespan of about 120 days ...
Lew, VL, Tiffert, JT
core +1 more source
Cell ReportsSummary: The transmembrane channel-like (TMC) protein family comprises eight members, with TMC1 and TMC2 being extensively studied. This study demonstrates substantial co-expression of TMC7 with the mechanosensitive channel Piezo2 in somatosensory ...
Xiaoxue Zhang +16 more
doaj +1 more source
TMEM150C/Tentonin3 Is a Regulator of Mechano-gated Ion Channels
Cell Reports, 2018 Summary: Neuronal mechano-sensitivity relies on mechano-gated ion channels, but pathways regulating their activity remain poorly understood. TMEM150C was proposed to mediate mechano-activated current in proprioceptive neurons. Here, we studied functional
Evan O. Anderson +4 more
doaj +1 more source
The Role of PIEZO2 in Human Mechanosensation.
Acta medica Iranica, 2017 No ...
Nima Rezaei, Amene Saghazadeh
openaire +2 more sources