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The mechanosensitive ion channel Piezo2 mediates sensitivity to mechanical pain in mice
Science Translational Medicine, 2018 The brush of a feather and a pinprick are perceived as distinct sensations because they are detected by discrete cutaneous sensory neurons. Inflammation or nerve injury can disrupt this sensory coding and result in maladaptive pain states, including ...
Swetha Murthy +2 more
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PKA mediates modality-specific modulation of the mechanically gated ion channel PIEZO2
Journal of Biological Chemistry, 2023Clement Verkest +2 more
exaly
Piezo2 Channel Upregulation is Involved in Mechanical Allodynia in CYP-Induced Cystitis Rats
Molecular Neurobiology, 2023Xiulin Zhang, Shulu Zu
exaly
Piezo2 integrates mechanical and thermal cues in vertebrate mechanoreceptors
Proceedings of the National Academy of Sciences of the United States of America, 2019Wang Zheng +2 more
exaly
Merkel cells and Meissner's corpuscles in human digital skin display Piezo2 immunoreactivity
Journal of Anatomy, 2017Jorge Garcia Piqueras +2 more
exaly