Results 121 to 130 of about 433,754 (318)

Ferritinophagy Rewires Carnitine‐Dependent Lipid Metabolism to Inhibit PRRSV and IAV Replication

Advanced Science, EarlyView.
NCOA4‐mediated ferritinophagy reprograms carnitine metabolism by disrupting Fe‐S cluster biogenesis, thereby establishing an iron‐lipid axis that suppresses various viruses, including PRRSV and IAV. However, viruses counteract this mechanism by degrading NCOA4.
Kaifeng Guan, Chenyang Yuan, Zekun Meng, Yanan Wang, Xueying Zhai, Chunjie Huang, Xiang Zhou, Gaiping Zhang   +7 more
wiley   +1 more source

Metabolomic-genomic prediction realizes small increases in accuracy of estimated breeding values for daily gain in pigs

Genetics Selection Evolution
Background Metabolomic profiling of blood samples can be done on selection candidates and could be a valuable information source for genetic evaluation of pigs.
Xiangyu Guo, Pernille Sarup, Anders Bay Nord, Mark Henryon, Tage Ostersen, Ole F. Christensen   +5 more
doaj   +1 more source

A Humanized Anti‐gD Broadly Neutralizing Antibody Confers Complete Post‐Exposure Protection against Pseudorabies Virus

Advanced Science, EarlyView.
Pseudorabies virus (PRV), an emerging zoonotic α‐herpesvirus, causes life‐threatening human encephalitis. We identified a broad‐spectrum neutralizing antibody 6F7 targeting PRV gD. It blocks gD‐Nectin‐1 binding and membrane fusion, inhibiting replication across all PRV variants, representing a promising candidate for anti‐PRV therapy.
Yue Sun, Jianbo Liu, Shi‐Jia Xu, Meng‐Xin Wang, Hongliang Zhang, Yanhe Zhang, Zhi‐Jun Tian, Jin‐Mei Peng, Xin Yin, Tong‐Qing An, Xue‐Hui Cai, Yan‐Dong Tang   +11 more
wiley   +1 more source

Agglomeration Externalities and Technical Efficiency in Pig Production [PDF]

The objective of the paper is to assess the effects of agglomeration on technical efficiency of French pig farms. We use a two-stage method to evaluate the effects of agglomeration on technical efficiency.
Larue, S., Latruffe, Laure
core   +1 more source

A Strong Lewis Acidic Diethylsilylium Catalyst for Direct Sulfonamidation of Challenging Ketones

Advanced Science, EarlyView.
Low‐substitution‐order silylium ions (R2HSi+) exhibit exceptional Lewis acidic activity. We report diethylsilylium‐catalyzed reductive sulfonamidation of functionalized ketones to access β‐amino esters. The in situ generated ion pair shows enhanced reactivity, with diethylsilane serving as both reductant and precatalyst. The developed protocol proceeds
Woo Hee Kim, Muhammad Israr, You Kyoung Chung, Shinwon Ham, Joonsuk Huh, Han Yong Bae   +5 more
wiley   +1 more source

Locating some quantitative genes in the pig [PDF]

, 1993
Locating genes on the pig genome will facilitate genetic improvement in pig productivity. Substituting portions of the chromosome (haplotypes) with standard haplotypes containing marker genes and observing changes in a quantitative trait can help to ...
McPhee, Cameron P.
core  

A Multimodal Magnetically Driven Soft Robot With Integrated Actuation‐Sensing Based on Photothermal Reprogramming Technology

Advanced Science, EarlyView.
This work reports a thermally safe, photothermally reprogrammable magnetic soft robot with its reprogramming temperature tuned to ∼39.5°C for biocompatibility. It achieves multimodal locomotion (max speed of 1.8 BL/s) and integrates liquid‐metal capacitive sensing to monitor self‐motion and detect environmental changes in simulated gastric environments,
Liu Yang, Yuliao Dong, Kangning Li, Cheng Jing, Ben Wang, Lin Xu   +5 more
wiley   +1 more source

Method analysis for a novel trait: comparing locations for haemoglobin sampling in piglets [PDF]

, 2014
Haemoglobin (Hb) testing on farm is a new technology within the pig industry that can be used for improving survival in piglets (Rootwelt et al., 2012) and as a selection criterion for iron content in pork (Hermesch and Jones, 2012). The testing requires
Hermesch, Susanne, Tickle, K M, Collins, C L   +2 more
core  

Discovery and Engineering of a Rat Endogenous Retrovirus Reverse Transcriptase for Efficient Prime Editing

Advanced Science, EarlyView.
We screened 558 reverse transcriptases and engineered an optimized rat endogenous retrovirus‐derived variant, enRERV‐RT, via structure‐guided engineering and deep mutational scanning. This enhanced prime editor, based on the engineered RT, outperforms conventional M‐MLV‐RT systems across plant and animal cells, particularly at hard‐to‐edit loci ...
Linsha Ma, Pengcheng Yao, Shengqi Wu, Yuanyuan Shi, Lang Qin, Baitao Li, Jiayi Zhu, Minhua Huang, Yichong Zhu, Yuwen Song, Jinhuan Pang, Ziping Guo, Guochuan Wu, Chen Wang, Kewei Xu, Ruihua Huang, Quan Kuang, Liang Qu, Changtian Pan, Xianrong Xie, Qinlong Zhu, Jiaying Huang, Qiupeng Lin   +22 more
wiley   +1 more source

Health Planner Pigs as an Instrument for Monitoring and Evaluation of Animal Health Care on Pig Farms [PDF]

In order to support animal health care on pig farms a Health Planner Pigs has been developed. In 1998 the practical value of the system was tested under field condition on pig farms.
van Buiten, A., Bokma-Bakker, Martien H.
core   +1 more source