Results 131 to 140 of about 497,798 (324)

Delivery of Human iPSC‐Derived RPE Cells in Healthy Minipig Retina Results in Interaction Between Photoreceptors and Transplanted Cells

open access: yesAdvanced Science, EarlyView.
Human induced pluripotent stem cell‐derived retinal pigment epithelial (hiPSC‐RPE) cells, cultured on a clinically relevant PDLLA scaffold, are transplanted into immunosuppressed minipigs. The study demonstrates the viability, integration, and preservation of RPE‐specific features without gliosis or neuroinflammation, supporting their potential as a ...
Anna Macečková Brymová   +27 more
wiley   +1 more source

A rare case of giant panda cancer: Pancreatic ductal adenocarcinoma

open access: yesAnimal Models and Experimental Medicine, Volume 5, Issue 6, Page 582-586, December 2022., 2022
Pancreatic tissues' tumors exhibited three different situations. (A) Several glandular tubular adenocarcinoma structures could be seen in pancreatic tissue. (B) Tubular area could be seen in the pancreas, exhibiting papillary growth in the area.
Yunsheng Wang   +6 more
wiley   +1 more source

DPImpute: A Genotype Imputation Framework for Ultra‐Low Coverage Whole‐Genome Sequencing and its Application in Genomic Selection

open access: yesAdvanced Science, EarlyView.
DPImpute is a two‐step pipeline that outperforms existing tools in whole‐genome SNP imputation, particularly under conditions of ultra‐low coverage sequencing, small sample sizes, and limited references. It enables precise imputation for single blastocyst cells, supporting genomic selection at the pre‐implantation stage.
Weigang Zheng   +11 more
wiley   +1 more source

"Hello, is this Anna?": A First Look at Pig-Butchering Scams [PDF]

open access: yesarXiv
Pig-butchering scams, or Sha Zhu Pan, have emerged as a complex form of cyber-enabled financial fraud that combines elements of romance, investment fraud, and advanced social engineering tactics to systematically exploit victims. In this paper, we present the first qualitative analysis of pig-butchering scams, informed by in-depth semi-structured ...
arxiv  

Fractions of Pig Complement [PDF]

open access: bronze, 1956
Myron A. Leon   +2 more
openalex   +1 more source

High‐Conductivity, Self‐Healing, and Adhesive Ionic Hydrogels for Health Monitoring and Human‐Machine Interactions Under Extreme Cold Conditions

open access: yesAdvanced Science, EarlyView.
This study presents an ionic conductive hydrogel (ICH) with excellent conductivity, self‐healing, self‐adhesion, and long‐term stability under extreme cold conditions. It shows significant potential for non‐invasive, continuous health monitoring, conformally adhering to skin without signal crosstalk, enabling real‐time, high‐fidelity signal ...
Fei Han   +12 more
wiley   +1 more source

Genomic Insights into Post‐Domestication Expansion and Selection of Body Size in Ponies

open access: yesAdvanced Science, EarlyView.
The authors’ research delves into the history of ponies by assembling a pony genome and integrating horse genomes. This unveils genetic connections between Asian and European pony breeds. Cis‐regulatory elements of key genes impacting body size are also identified.
Xingzheng Li   +23 more
wiley   +1 more source

Machine Learning‐Enabled Drug‐Induced Toxicity Prediction

open access: yesAdvanced Science, EarlyView.
Unexpected toxicity accounts for 30% of drug development failures. This review highlights ML innovations in predicting drug‐induced toxicity, emphasizing comparative analyses, interpretable algorithms, and multi‐source data integration. It categorizes toxicity types, summarizes ML models, and organizes key databases, offering strategies to address ...
Changsen Bai   +5 more
wiley   +1 more source

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