Results 101 to 110 of about 70,259 (327)

Elevated plasma levels of pigment epithelium-derived factor correlated with inflammation and lung function in COPD patients

International Journal of COPD, 2015
Xiaoou Li,1–3 Tao Wang,1,2 Ting Yang,1,2 Yongchun Shen,1,2 Jing An,1,2 Lian Liu,1,2 Jiajia Dong,1,2 Lingli Guo,1,2 Diandian Li,1,2 Xue Zhang,1,2 Lei Chen,1,2 Dan Xu,1,2 Fuqiang Wen1,2 1Division of Pulmonary Diseases, State Key Laboratory of ...
Li X, Wang T, Yang T, Shen Y, An J, Liu L, Dong J, Guo L, Li D, Zhang X, Chen L, Xu D, Wen F   +12 more
doaj  

Pigment Epithelium-Derived Factor Blocks Tumor Extravasation by Suppressing Amoeboid Morphology and Mesenchymal Proteolysis

Neoplasia: An International Journal for Oncology Research, 2011
Metastatic melanoma cells are highly adaptable to their in vivo microenvironment and can switch between protease-dependent mesenchymal and protease-independent amoeboid invasion to facilitate metastasis. Such adaptability can be visualized in vitro, when
Omar Ladhani, Cristina Sánchez-Martinez, Jose L Orgaz, Benilde Jimenez, Olga V Volpert   +4 more
doaj   +1 more source

High-risk corneal allografts : A therapeutic challenge [PDF]

, 2016
Peer reviewedPublisher ...
Forrester, John V, Griffith, May, Kuffová, Lucia, Rajendran, Vijayalakshmi, Yu, Tian   +4 more
core   +1 more source

Age‐related differences in hydroxychloroquine‐associated adverse events: A pharmacovigilance study based on the FDA Adverse Event Reporting System

British Journal of Clinical Pharmacology, EarlyView.
Aims This real‐world pharmacovigilance study utilizes FDA Adverse Event Reporting System (FAERS) data (2004–2024) to characterize age‐related disparities in hydroxychloroquine (HCQ)‐associated adverse events (AEs), addressing gaps in age‐stratified risk assessment. Methods Disproportionality analysis (reporting odds ratios, RORs) and parametric Weibull
Guanghan Sun, Jingrong Yang, Lei Wan, Xia Xu, Jing Wang   +4 more
wiley   +1 more source

Pigment Epithelium-Derived Factor Promotes Axon Regeneration and Functional Recovery After Spinal Cord Injury

Molecular Neurobiology, 2019
Although neurons in the adult mammalian CNS are inherently incapable of regeneration after injury, we previously showed that exogenous delivery of pigment epithelium-derived factor (PEDF), a 50-kDa neurotrophic factor (NTF), promoted adult retinal ...
Andrew R. Stevens, U. Ahmed, V. Vigneswara, Zubair Ahmed   +3 more
semanticscholar   +1 more source

Sorafenib prevents human retinal pigment epithelium cells from light-induced overexpression of VEGF, PDGF and PlGF [PDF]

, 2010
Background Cumulative light exposure is significantly associated with progression of age-related macular degeneration (AMD). Inhibition of vascular endothelial growth factor is the main target of current antiangiogenic treatment strategies in AMD ...
Alge, C. S., Hirneiß, Christoph, Kampik, Anselm, Kernt, Marcus, Liegl, R. G., Neubauer, A. S., Ulbig, Michael W., Wolf, Armin   +7 more
core   +3 more sources

Marine silicon for biomedical sustainability

BMEMat, EarlyView.
Schematic illustrating marine silicon for biomedical engineering. Abstract Despite momentous divergence from oceanic origin, human beings and marine organisms exhibit elemental homology through silicon utilization. Notably, silicon serves as a critical constituent in multiple biomedical processes.
Yahui Han, Zhibo Yang, Wei Xia, Chengtie Wu   +3 more
wiley   +1 more source

Anti-angiogenic and anti-inflammatory effects of SERPINA3K on corneal injury. [PDF]

PLoS ONE, 2011
SERPINA3K is a member of the serine proteinase inhibitor (SERPIN) family. Here we evaluated the therapeutic effects of SERPINA3K on neovascularization and inflammation in a rat cornea alkali burn model that is commonly employed to study corneal wounding.
Xiaochen Liu, Zhirong Lin, Tong Zhou, Ronrong Zong, Hui He, Zhen Liu, Jian-xing Ma, Zuguo Liu, Yueping Zhou   +8 more
doaj   +1 more source

Defining a mechanistic link between pigment epithelium–derived factor, docosahexaenoic acid, and corneal nerve regeneration

Journal of Biological Chemistry, 2017
The cornea is densely innervated to sustain the integrity of the ocular surface. Corneal nerve damage produced by aging, diabetes, refractive surgeries, and viral or bacterial infections impairs tear production, the blinking reflex, and epithelial wound ...
T. Pham, Jiucheng He, Azucena H. Kakazu, Bokkyoo Jun, N. Bazan, H. Bazan   +5 more
semanticscholar   +1 more source

Age and diabetes related changes of the retinal capillaries: an ultrastructural and immunohistochemical study [PDF]

, 2015
Normal human aging and diabetes are associated with a gradual decrease of cerebral flow in the brain with changes in vascular architecture. Thickening of the capillary basement membrane and microvascular fibrosis are evident in the central nervous system
ARTICO, Marco, BATTAGLIONE, Ezio, BIANCHI, ENRICA, Feher, Janos, Kovacs, Illes, MAGLIULO, Giuseppe, Micera, Alessandra, ORLANDO, Maria Patrizia, PLATEROTI, Rocco, Ripandelli, Guido, TAURONE, SAMANTA   +10 more
core   +1 more source