Results 221 to 230 of about 70,259 (327)

Functional Roles of Pigment Epithelium-Derived Factor in Retinal Degenerative and Vascular Disorders: A Scoping Review. [PDF]

Invest Ophthalmol Vis Sci
Jakobsen TS, Adsersen RL, Askou AL, Corydon TJ.   +3 more
europepmc   +1 more source

Glucose Variability is Independently Correlated with Serum Level of Pigment Epithelium-Derived Factor in Type 2 Diabetes. [PDF]

Diabetes Ther, 2021
Fujikawa T, Ohara M, Kohata Y, Nagaike H, Fukase A, Osaka N, Yashima H, Sato N, Kushima H, Shinmura K, Takahashi Y, Hiromura M, Terasaki M, Mori Y, Fukui T, Matsui T, Hirano T, Yamagishi SI.   +17 more
europepmc   +1 more source

Spleen Tyrosine Kinase (SYK) is Necessary for cGAS‐STING Signaling in Müller Glia and Visual Function Deficits in Diabetic Mice

Glia, Volume 74, Issue 6, June 2026.
Hyperglycemic conditions increased mitochondrial membrane permeability and inflammatory signaling in Müller cells via cGAS‐STING activation. SYK was necessary for cGAS–STING activation and increased cytokine expression in Müller cells. Müller glia‐specific SYK deletion reduced glial activation and attenuated inflammatory cytokine expression in the ...
Esma I. Yerlikaya, Siddharth Sunilkumar, Sandeep M. Subrahmanian, Allyson L. Toro, Clay T. Yeager, Kashif A. Shaikh, Edward W. Harhaj, Alistair J. Barber, Michael D. Dennis   +8 more
wiley   +1 more source

Pigment Epithelium-Derived Factor Inhibits Cell Motility and p-ERK1/2 Signaling in Intrahepatic Cholangiocarcinoma Cell Lines. [PDF]

Biology (Basel)
Porreca V, Corbella E, Palmisano B, Peres M, Angelone P, Barbagallo C, Stella M, Mignogna G, Mennini G, Melandro F, Rossi M, Ragusa M, Corsi A, Riminucci M, Maras B, Mancone C.   +15 more
europepmc   +1 more source

A Dynamic Change of Microglial States Occurs During the Transition From Photoreceptor Degeneration to Regeneration in Zebrafish pde6c Mutants

Glia, Volume 74, Issue 6, June 2026.
Zebrafish pde6c mutants undergo photoreceptor degeneration from 5 dpf, but rods regenerate from 4 wpf. scRNA‐seq of retinal microglia reveals dynamic change of states between 5 dpf and 4 wpf. Two states emerge specifically during regeneration. ABSTRACT Microglia, brain‐resident immune cells, maintain brain homeostasis.
Darshini Ravishankar, Yuki Takeuchi, Ichiro Masai   +2 more
wiley   +1 more source

In silico characterisation and chromosomal localisation of human RRH (peropsin) – implications for opsin evolution [PDF]

, 2003
Bellingham, J, Foster, R G, Wells, D J
core   +1 more source

HIF2A as a prognostic and clinical therapeutic target in ovarian clear cell carcinoma

International Journal of Cancer, Volume 158, Issue 11, Page 2957-2971, 1 June 2026.
What's new? Ovarian clear cell carcinoma is highly associated with hypoxia. Hypoxia‐inducible factor 2A (HIF2A) is a key regulator of hypoxic responses, but its role in ovarian clear cell carcinoma remains unclear. This study demonstrated the unfavorable prognostic significance of HIF2A expression in ovarian clear cell carcinoma.
Mengxin Jiang, Ken Yamaguchi, Kohei Hamada, Yuko Hosoe, Yuka Mise, Sachiko Kitamura, Zhihong Liu, Hairong Wei, Zhenhai Gao, Mana Taki, Koji Yamanoi, Ryusuke Murakami, Rin Mizuno, Taito Miyamoto, Junzo Hamanishi, Masaki Mandai   +15 more
wiley   +1 more source

Pigment Epithelium-Derived Factor Binding to VEGFR-1 (Flt-1) Increases the Survival of Retinal Neurons. [PDF]

Invest Ophthalmol Vis Sci
Meng J, Yang XM, Scheer O, Lange J, Müller H, Bürger S, Rothemund S, Younis R, Unterlauft JD, Eichler W.   +9 more
europepmc   +1 more source

Improving Meat Analogues With Pea Proteins: A Comprehensive Review of Applications, Allergenicity, and Safety

Legume Science, Volume 8, Issue 2, June 2026.
ABSTRACT With the growing global population and change in consumers' lifestyles, there is a pressing need for sustainable, safe, and nutritious sources of protein. Alternative proteins, like plant‐based meat supplemented with pea protein, offer a promising source; however, knowledge of their application, allergenicity, and safety is limited, and the ...
Ahmadullah Zahir, Muhammad Junaid Anwar, Muhammad Hammad Anwar, Huma Arif, Abuzar, Priya Pravin Bora, Ghazaleh Ahmadi Partovi   +6 more
wiley   +1 more source

Colorectal Precancerous Lesions: Molecular Mechanisms, Research Tools, and Natural Product‐Based Clinical Translation

MedComm – Oncology, Volume 5, Issue 2, June 2026.
This article systematically elucidates the molecular mechanisms of colorectal precancerous lesions, introduces cutting‐edge research tools like multi‐omics and organoids, and highlights the potential and prospects of natural products such as berberine, resveratrol, and curcumin in preventing and intervening in colorectal carcinogenesis by modulating ...
Shunji Liu, Chujuan Cui, Lingdong Kong, Qiang Xu, Haibo Cheng, Lisha Zhou, Yang Sun   +6 more
wiley   +1 more source