Results 211 to 220 of about 2,960,448 (354)

New insights into applications of base editor in hereditary disorders

Interdisciplinary Medicine, EarlyView.
Abstract Hereditary disorders are a group of diseases caused by genetic mutations or chromosomal variations. Although the incidence of each genetic disorder is relatively low, patients affected by the disease generally experience a range of severe symptoms, including blindness, disability, and even premature death. In addition, the available treatments
Maoping Cai, Linhui Zhang, Liqing Li, Yue Liu, Canbin Lv, Yan Shi, Jianyuan Zhao, Dingwei Ye, Yuanyuan Qu   +8 more
wiley   +1 more source

Daidzin suppresses melanogenesis through ERK and AKT signaling pathways mediated MITF proteasomal degradation

Experimental and Molecular Pathology
Daidzin, a prominent isoflavone found in soybeans, Pueraria lobata, and various legumes, has been extensively investigated for its diverse pharmacological activities, which include anticancer, antioxidant, anti-inflammatory, antiepileptic, and alcohol ...
Jinpeng Lv, Kun Zou, Chuanwei Yin, Wenhui Xu, Duo Meng, Huansha Zhang, Wenhao Yu, Peiwen Jiang, Changjun Yun, Hui Xue, Nan Hu, Rongyin Gao   +11 more
doaj  

Orthotopic liver transplantation for hemochromatosis [PDF]

, 1991
Kakizoe, S, Pillay, P, Starzl, TE, Tzakis, AG, Tzoracoleftherakis, E, Van Thiel, DH   +5 more
core  

Microsaccades Tracking by Secondary Speckle Pattern Analysis

Journal of Biophotonics, EarlyView.
A new approach for detecting microsaccades is introduced using secondary speckle patterns reflected from the sclera. This method offers potential benefits in capturing subtle eye movements and overcoming limitations in traditional pupil‐tracking systems.
Ola Shteinberg, Sergey Agdarov, Yafim Beiderman, Yoram S. Bonneh, Inbal Ziv, Zeev Kalyuzhner, Zeev Zalevsky   +6 more
wiley   +1 more source

Lipidome Complexity in Physiological and Pathological Skin Pigmentation. [PDF]

Int J Mol Sci
Bastonini E, Kovacs D, Maresca V, Ottaviani M, Di Nardo A, Flori E, Cardinali G, Briganti S.   +7 more
europepmc   +1 more source

Unstained Blood Smear Analysis: A Review of Rule‐Based, Machine Learning, and Deep Learning Techniques

Journal of Biophotonics, EarlyView.
Bright‐field images of unstained smears. (1) Sparse erythrocytes allow straightforward intensity‐ or phase‐based segmentation. (2) Overlapping cells blur boundaries, causing over‐ or under‐segmentation and lowering rule‐based accuracy, thus motivating overlap‐aware algorithms for reliable downstream feature extraction and classification. ABSTRACT Blood
Husnu Baris Baydargil, Thomas Bocklitz
wiley   +1 more source

Melanocyte dysfunctions: future and promise of stem cells. [PDF]

Am J Stem Cells
Ali SA, Kassab G, Husain T.
europepmc   +1 more source

Exploring the Therapeutic Potential of Exosomes in Pigmentation Disorders

Daniela Rizzo, Joseph Largen, Nicole Weinhold, Elma Mohammed, Quinn Schroeder, Nisar Ahmed   +5 more
openalex   +1 more source

Use of Mitochondrial Delayed Luminescence Measurements From Brain Tissue to Optimize Photobiomodulation Prarameters in Alzheimer's Disease Mice

Journal of Biophotonics, EarlyView.
Photobiomodulation (808 nm laser, optimized at 80 Hz, 30% duty cycle) significantly enhances mitochondrial function, reduces β‐amyloid deposition, and attenuates microglial activation in a 5XFAD Alzheimer's mouse model. Delayed luminescence serves as a novel bioenergetic marker, linking improved mitochondrial efficiency to cognitive and ...
Hong Bae Kim, Chang Kyu Sung
wiley   +1 more source

The Role of Tyrosine Kinase in Beauty and Skincare: A Comprehensive Review. [PDF]

J Cosmet Dermatol
Li Z.
europepmc   +1 more source