Results 91 to 100 of about 132,129 (241)

Behavior of Vertical Piles in Layered Soils Under the Influence of Vertical and Lateral Loading Conditions

open access: yesBuildings
Pile foundations used for structures, such as tall buildings and bridges, especially in coastal and heavily flooded areas, experience uncertain lateral loads.
A. Priyadharshini, V. K. Stalin
doaj   +1 more source

Foundation Technology Development Of Hydraulic Structure On Peat Soil

open access: yesJurnal Teknik Hidraulik, 2018
Many hydraulic structures in Indonesia are built on peat soil, especially in Sumatra, Kalimantan and Papua. This soil has bad geotechnical characteristic for building foundation, because its low of shear strength, high potential of land subsidence and ...
Mahdi Ibrahim Tanjung   +2 more
doaj   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

open access: yesMolecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Przedmioty sacrum w zbiorach działu sztuki Muzeum Okręgowego w Pile

open access: yesRocznik Skrzatuski
The above article discusses sacred objects collected in the art department of the District Museum in Pila (Piła). The discussed exhibits come from the books: Paintings, Sculpture, Ceramics and Glass, and Utility Objects.
Zuzanna Miłobędzka
doaj   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Meeks Estate, Marrickville [cartographic material] : for sale on the ground Saty. 23rd, Octr. at 3.30 /

open access: yes, 1880
Sales plan for land in the suburb of Marrickville in Sydney, bordered by Addison Road, Shepherd Street, Handley Street, Meeks Street, and Illawarra Road.; At head of title: 17 choice villa sites.; "Terms: 5 deposit on each lot, and the balance 18 equal ...
Mills & Pile.
core  

THE EFFECTS OF WATER CONTENT VARIATION ON ADHESION FACTOR OF PILE FOUNDATION IN EXPANSIVE SOIL [PDF]

open access: yes, 2013
Seasonal change causes variations in soil moisture content. On expansive soil, this condition influences soil moisture content in the active zone, which is approximately in five meters depth.
Soemitro, Ria Asih Aryani   +2 more
core  

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

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