Results 71 to 80 of about 34,715 (269)
Międzynarodowy Festiwal Muzyki Religijnej im. ks. Stanisława Ormińskiego w Rumi (20-22.10.2016)
Seminare, 2022 Krzysztof Niegowski
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COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
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Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
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Static pile-soil-pile interaction in offshore pile groups
, 1994 This thesis is a theoretical study, using both finite element and boundary element methods, of the behaviour of single-piles and pile groups under vertical and lateral loading. It offers an improved understanding of the soil-structure interaction that occurs in pile groups, particularly closely spaced piles subjected to lateral loads.
Chaudhry, A, Chaudhry, A. R.
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Comparison of the Behavior for Free Standing Pile Group and Piles of Piled Raft
Engineering and Technology Journal, 2018 The intended task of this paper is studying the behavior of free standing pile groups and piles of piled raft driven in clayey soil under axial loading. The raft-piles interaction is investigated as well through the two series of tests. Each one of these series includes twelve tests, the two series are conducted with the same configuration, spacing ...
Awf Al-Kaisi +2 more
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Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
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Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
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BuildingsThis paper develops a nonlinear strain wedge (SW) model for analyzing laterally loaded piles installed in the proximity of sandy slopes, with consideration of slope surface deformation.
Wei Wang, Lingzhi Zhang
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Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
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