Results 81 to 90 of about 214,688 (304)

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Influence of Pile Foundation Construction on Existing Tunnels in a Metro Protection Area: Field Test and Numerical Simulation

open access: yesBuildings
On the basis of the Fengqi Chaoming project in Hangzhou City, Zhejiang Province, China, this paper investigates the influence of pile foundation construction on the existing tunnels in a metro protection area to ensure the stability and safety of the ...
Gang Lin   +6 more
doaj   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Analysis of the effect and influencing factors of CFG pile composite foundation treatment in west Sichuan high-plateau airport

open access: yesJournal of Asian Architecture and Building Engineering
In this study, the finite element model (FEM) of the CFG pile composite foundation underlayered filling of the high-fill embankments was established by numerical simulation to analyze the treatment effect and influencing factors of CFG pile composite ...
Yanjun Liu   +7 more
doaj   +1 more source

Dynamic Response Difference of Single Pile and Pile Group with Variable Section in Variation of Seismic Subsidence Soil Layer

open access: yesShanghai Jiaotong Daxue xuebao
In order to study the difference of dynamic response between large diameter variable section single pile and pile group foundations in seismic subsidence soil with different thicknesses under ground motion, based on the Xiang’an Bridge of Xiamen Second ...
FENG Zhongju, WANG Wei, ZHANG Cong, ZHU Jixin, WANG Yiran, MENG Yingying
doaj   +1 more source

Temperature Distributions inside Concrete Sections of Renewable Energy Storage Pile Foundations

open access: yesApplied Sciences, 2019
A new pile foundation system is being developed for renewable energy storage through a multi-disciplinary research project. This system utilizes the compressed air technology to store renewable energy inside the reinforced concrete pile foundation ...
Dichuan Zhang   +5 more
doaj   +1 more source

Design optimisation of reinforced concrete pile foundation using generalised reduced gradient algorithm [PDF]

open access: diamond, 2022
Jamiu A. Dauda   +4 more
openalex   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Analysis of micro characteristics and influence factors of foundation pit failure [PDF]

open access: yes, 2015
Combined with the design data of an actual foundation pit, PFC (Particle Flow Code) model was developed and micro characteristics such as porosity, displacement vector field and particle rotation were analyzed when a foundation pit with cantilever ...
Fang, X., Fonseca, J., Hu, Z., Li, Y. Q.
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