Results 71 to 80 of about 13,437 (268)

EMBEDDED IN SANDY SOILS WITH CAVITIES

Journal of Engineering, 2007
A program of laboratory testing is carried out to study the performance of laterally loaded piles embedded in soil, which contains cavities. The testing apparatus is manufactured for carrying out the tests and a simple technique was used to simulate the
Mosa J. Al-Mosawe, Yousif J. Al-Shakarchi, Saheem M. Al-Taie   +2 more
doaj   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Experimental study on lateral pile-soil pressure on passive part of pile groups in innovative sheet-pile wharf

Yantu gongcheng xuebao, 2018
The pile group of vertical cast-in-place piles with relief platform has been successfully introduced into innovative sheet-pile wharfs to withhold lateral load due to horizontal soil movement along with its front wall.
XU Guang-ming 1,2, REN Guo-feng 1,2, GU Xing-wen 1,2, CHEN Ai-zhong 3, LI Le-chen 4
doaj   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Experimental Study of Negative Skin Friction of Pile Group Foundations for Offshore Wind Turbines on Artificial Islands

Journal of Marine Science and Engineering
Constructing offshore wind turbines on artificial islands is considered a viable option, but negative skin friction (NSF) is a significant adverse factor that cannot be ignored.
Yeyu Yan, Guoliang Dai, Zhiwei Chen, Tao Hu, Weiming Gong, Chenchen Shi   +5 more
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Determination method for horizontal load-bearing capacity of pile group for large LNG tank

You-qi chuyun
Objective The pile group foundation for large LNG tanks is subjected to relatively large horizontal forces under two seismic conditions: Operating Basis Earthquake (OBE) signifying a 10% probability of exceedance within a 50-year period and Safe Shutdown
Chengguo WEI, Hanwen WANG, Wentao LIU, Wei CUI, Wangyu ZHAN   +4 more
doaj   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source