Results 81 to 90 of about 235,431 (305)

Contact dynamics in a gently vibrated granular pile [PDF]

, 2003
We use multi-speckle diffusive wave spectroscopy (MSDWS) to probe the micron-scale dynamics of a granular pile submitted to discrete gentle taps. The typical time-scale between plastic events is found to increase dramatically with the number of applied ...
A. Knaebel, Alexandre Kabla, C. Lesaffre, D. J. Durian, G. Maret, Georges Debrégeas, J. Desrues, J.-P. Bouchaud, K. Kim, L. Cipelletti, M. Da Silva, P. Philippe   +11 more
core   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Flexible Pile Group Interaction Factors under Arbitrary Lateral Loading in Sand

Journal of Marine Science and Engineering, 2020
Marine and harbor structures, wind turbines, bridges, offshore platforms, industrial chimneys, retaining structures etc. can be subjected to significant lateral loads from various sources.
Miloš Marjanović, Mirjana Vukićević, Diethard König   +2 more
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Formative exploration of students’ perception about Community Medicine teaching at Mahatma Gandhi Institute of Medical Sciences, Sewagram, India [PDF]

, 2008
Objective: The objectives of the present formative research were to explore the medical undergraduates’ study problems and their perceptions about various teaching approaches in currently practiced teaching curriculum of Community Medicine.
Deshmukh, PR, Dongre, AR, Garg, BS
core   +1 more source

How Can Geography and Mobile Phones Contribute to Psychotherapy? [PDF]

, 2017
Interdisciplinary relationships between Geography and Psychotherapy are an opportunity for innovation. Indeed, scientific works found on bibliographic databases and concerning this theme are scarce.
Aguilera, Adrián, Ferrás, Carlos, García, Yolanda, Rocha, Álvaro   +3 more
core   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

EMBEDDED IN SANDY SOILS WITH CAVITIES

Journal of Engineering, 2007
A program of laboratory testing is carried out to study the performance of laterally loaded piles embedded in soil, which contains cavities. The testing apparatus is manufactured for carrying out the tests and a simple technique was used to simulate the
Mosa J. Al-Mosawe, Yousif J. Al-Shakarchi, Saheem M. Al-Taie   +2 more
doaj   +3 more sources

Laboratory Study of Local Scour Around an Array of Pile Groups in Clear-Water Scour Conditions

Journal of Marine Science and Engineering
Current-induced local scour around pile groups weakens the capacity of structures. In this paper, experimental tests of local scour around an array of 5 × 5 pile groups were conducted in a steady current in a hydraulic flume.
Ming Gong, Xinying Pan, Shengtao Du, Guoxiang Wu, Yingxue Lv, Yunjia Sun, Guangjia Ding, Bingchen Liang   +7 more
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source