Results 41 to 50 of about 260,800 (246)

Influence of Spacing and Cross-Sectional Shaft of Screw Piles Group on Lateral Capacity

open access: yesDiyala Journal of Engineering Sciences, 2021
Although there are several high-capacity screw piles in use currently, there are few studies on their lateral performance. The aim of this study is to investigate the lateral behaviour of several models of screw pile group (1×2), (2×1), and (2×2 ...
Azhar Subhi, Hassan O. Abbas
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Research on Bearing Characteristics of Offshore Inclined Helical Pile-Group Foundations in Sandy Soil

open access: yes南方能源建设
[Introduction] The offshore wind power industry is among the most pioneering and strategic emerging sectors in the global development of new energy sources.
Weihua YANG   +4 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Estimation of axially-loaded bored piles interaction in the design of pile foundation/Centriškai apkrautų gręžtinių polių tarpusavio sąveikos įvertinimas projektuojant polinius pamatus

open access: yesJournal of Civil Engineering and Management, 2001
In Lithuania and many foreign countries traditional approach of replacing the pile group by equivalent raft foundation in order to estimate settlements is used. But now we have another method. H. Poulos [3] described the influence between piles in a pile
Danutė Sližytė
doaj   +1 more source

Analytical solution for dynamic interaction of end-bearing pile groups subjected to vertical dynamic loads

open access: yesYantu gongcheng xuebao, 2022
An analytical model for pile-soil-vertical coupled vibration of the pile considering the scattering effects of the passive pile is proposed based on the classical plane strain assumption.
ZHENG Chang-jie 1, 2, CUI Yi-qin 1, 2, DING Xuan-ming 3, 4, LUAN Lu-bao 5
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

A Study on the Load-Bearing Characteristics and Load Transfer Mechanism of Bag Grouting Pile in Soft Soil Areas

open access: yesApplied Sciences, 2023
In soft soil areas, to compare the load-bearing characteristics of bag grouting piles and cement mixing piles and study the load-bearing mechanism of bag grouting piles, field tests are conducted in this study, including the comparative compressive test ...
Fei Meng, Yipu Peng
doaj   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Optimization of inter-helix spacing for helical piles in sand

open access: yesJournal of Rock Mechanics and Geotechnical Engineering, 2022
The optimization of the inter-helix spacing is a key issue of the axial bearing capacity of helical piles. In this paper, based on the cavity expansion, an analytical approach considering the small-strain stiffness, strength, compressibility and stress ...
Kang Shao   +5 more
doaj   +1 more source

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